What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,250 1,273
Depressed mood 1,604 787
Persistent depressive disorder (dysthymia) 393 320
Mild depression 153 65
Anxious mood 121 64

Show all 194 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
268
Moderate
376
Mild
610
None
1,111

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 105
Anxious mood 70
Weight gain 54
Insomnia 50
Headaches 48
Constipation 43

Show all 446 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 181
150 mg daily 135
100 mg daily 79
300 mg/24 hours daily 61
75 mg daily 54
450 mg daily 54
100 mg twice daily 35
150 mg twice daily 35
200 mg daily 28
150 mg/24 hours daily 26

See all 76 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 649
Side effects too severe 549
Doctor's advice 421
Other 274
Course of treatment ended 89
Expense 82
Personal research 70
Change in health plan coverage 43
See all 1582 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
1 - 6 months 48
6 months - 1 year 100
1 - 2 years 110
2 - 5 years 219
5 - 10 years 190
10 years or more 170

Stopped taking Bupropion

Duration Patients
Less than 1 month 350
1 - 6 months 352
6 months - 1 year 232
1 - 2 years 228
2 - 5 years 274
5 - 10 years 122
10 years or more 60
Adherence
Adherence Evaluations
Always 1850
Usually 352
Sometimes 53
Never taken as prescribed 110
Burden
Burden Evaluations
Very hard to take 80
Somewhat hard to take 146
A little hard to take 337
Not at all hard to take 1802
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 85
$25-49 174
< $25 1140
Not specified 928

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 94
Fluoxetine (Prozac) 87
Venlafaxine (Effexor XR) 72
Citalopram (Celexa) 51
Duloxetine (Cymbalta) 49

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Sertraline (Zoloft) 48
Duloxetine (Cymbalta) 46
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 31
Fluoxetine (Prozac) 30

Show all 46 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

Dec 15, 2017 (Started Jun 01, 2006)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Severe (insomnia, hot flashes, feeling tense or on edge, feeling feverish, facial flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: If you are taking the generic extended release make sure it is not dose dumping - releasing too much medicine at once causing side effects. My MS doctor, PCP, and I thought I was in menopause with all the hot flashes and fevers of 99.6! Even kept going in to see if I had a UTI bc of the fevers! What a waste of my time and money!!!
Cost: < $25 monthly

  • 0 helpful marks

Dec 1, 2017 (Started Jul 01, 2007)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Cost: $50-99 monthly

Apr 8, 2012 (Started Jul 01, 2007)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (morning nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: I use a pill organizer to keep track of whether or not I have taken my pills for the day and take them at the same time every day. I take pills at night when possible to minimize nausea.
Cost: $100-199 monthly

  • 0 helpful marks

Sep 19, 2017 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Mild (headaches)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 300 mg Daily
Cost: < $25 monthly

Sep 17, 2012 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (headaches)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Advice & Tips: Have someone you trust remind you to take the medicines. I have my wife who reminds me, although I have the medicine in the cupboard by the glasses. When I experience headaches with the buproprion, I take some Aleve or Motrin.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion