What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
major depressive disorder 2,086 1,196
Depressed mood 1,555 752
persistent depressive disorder (dysthymia) 366 304
mild depression 147 61
Anxious mood 120 64
bipolar disorder 105 91

Show all 213 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 249
Moderate 364
Mild 581
None 1,053

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 101
Anxious mood 64
Weight gain 54
Insomnia 49
Headaches 47
Constipation 41

Show all 429 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 173
150 mg daily 156
100 mg daily 105
75 mg daily 62
300 mg/24 hours daily 62
450 mg daily 57
150 mg twice daily 42
100 mg twice daily 37
200 mg daily 27
150 mg/24 hours daily 21

See all 86 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 608
Side effects too severe 511
Doctor's advice 395
Other 265
Course of treatment ended 85
Expense 80
Personal research 71
Change in health plan coverage 39
See all 1490 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 17
1 - 6 months 77
6 months - 1 year 81
1 - 2 years 140
2 - 5 years 241
5 - 10 years 203
10 years or more 172

Stopped taking Bupropion

Duration Patients
Less than 1 month 306
1 - 6 months 346
6 months - 1 year 239
1 - 2 years 212
2 - 5 years 258
5 - 10 years 114
10 years or more 55
Adherence
Adherence Evaluations
Always 1756
Usually 340
Sometimes 49
Never taken as prescribed 102
Burden
Burden Evaluations
Very hard to take 75
Somewhat hard to take 141
A little hard to take 331
Not at all hard to take 1700
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 84
$25-49 167
< $25 1087
Not specified 871

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 84
Fluoxetine (Prozac) 77
Venlafaxine (Effexor XR) 61
Citalopram (Celexa) 43
Duloxetine (Cymbalta) 43

Show all 53 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 44
Sertraline (Zoloft) 40
Venlafaxine (Effexor XR) 29
Citalopram (Celexa) 26
Fluoxetine (Prozac) 24

Show all 44 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion