What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,145 1,222
Depressed mood 1,564 768
Persistent depressive disorder (dysthymia) 375 312
Mild depression 150 63
Anxious mood 122 67

Show all 189 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 255
Moderate 368
Mild 589
None 1,074

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 103
Anxious mood 66
Weight gain 55
Insomnia 49
Headaches 46
Constipation 42

Show all 433 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 161
150 mg daily 140
100 mg daily 91
75 mg daily 57
300 mg/24 hours daily 53
450 mg daily 46
150 mg twice daily 40
100 mg twice daily 38
200 mg daily 25
150 mg/24 hours daily 22

See all 77 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 622
Side effects too severe 521
Doctor's advice 403
Other 266
Course of treatment ended 86
Expense 81
Personal research 71
Change in health plan coverage 40
See all 1519 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 6
1 - 6 months 75
6 months - 1 year 78
1 - 2 years 135
2 - 5 years 215
5 - 10 years 190
10 years or more 156

Stopped taking Bupropion

Duration Patients
Less than 1 month 317
1 - 6 months 348
6 months - 1 year 241
1 - 2 years 218
2 - 5 years 262
5 - 10 years 116
10 years or more 56
Adherence
Adherence Evaluations
Always 1785
Usually 346
Sometimes 52
Never taken as prescribed 103
Burden
Burden Evaluations
Very hard to take 77
Somewhat hard to take 143
A little hard to take 333
Not at all hard to take 1733
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 24
$50-99 84
$25-49 168
< $25 1109
Not specified 888

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 87
Fluoxetine (Prozac) 81
Venlafaxine (Effexor XR) 61
Citalopram (Celexa) 45
Duloxetine (Cymbalta) 45

Show all 54 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 43
Sertraline (Zoloft) 43
Venlafaxine (Effexor XR) 32
Citalopram (Celexa) 28
Fluoxetine (Prozac) 26

Show all 44 treatments patients report switching to

Last updated:

184 patient evaluations for Bupropion

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 184 patient evaluations for Bupropion