What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,928 1,109
Depressed mood 1,529 729
Persistent depressive disorder (dysthymia) 348 286
Mild Depression 140 56
Anxious mood 115 56
Bipolar Disorder 103 86

Show all 209 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 238
Moderate 343
Mild 560
None 983

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 96
Anxious mood 58
Weight gain 51
Insomnia 48
Headaches 47
Constipation 41

Show all 422 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 149
150 mg daily 145
100 mg daily 95
300 mg/24 hours daily 70
75 mg daily 52
450 mg daily 45
100 mg twice daily 40
150 mg twice daily 31
150 mg/24 hours daily 27
200 mg daily 21

See all 80 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 581
Side effects too severe 491
Doctor's advice 379
Other 257
Course of treatment ended 83
Expense 80
Personal research 68
Change in health plan coverage 39
See all 1430 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 8
1 - 6 months 75
6 months - 1 year 92
1 - 2 years 139
2 - 5 years 186
5 - 10 years 191
10 years or more 144

Stopped taking Bupropion

Duration Patients
Less than 1 month 286
1 - 6 months 341
6 months - 1 year 228
1 - 2 years 209
2 - 5 years 247
5 - 10 years 109
10 years or more 51
Adherence
Adherence Evaluations
Always 1657
Usually 326
Sometimes 46
Never taken as prescribed 95
Burden
Burden Evaluations
Very hard to take 73
Somewhat hard to take 132
A little hard to take 321
Not at all hard to take 1598
Cost per month
Cost per month Evaluations
$200+ 12
$100-199 25
$50-99 80
$25-49 159
< $25 1037
Not specified 811

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 72
Fluoxetine (Prozac) 61
Venlafaxine (Effexor XR) 57
Duloxetine (Cymbalta) 38
Citalopram (Celexa) 37

Show all 49 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 42
Sertraline (Zoloft) 35
Venlafaxine (Effexor XR) 26
Citalopram (Celexa) 21
Fluoxetine (Prozac) 21

Show all 42 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,628 members have decided to share their profiles only with other members of PatientsLikeMe.

LadySirona
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LadySirona
Gender: F
Data Quality: 2 stars
Depression: 2
Mania: 1
Emotional: 1
Anxiety: 2
Compulsion: 2
External Stress: Overwhelming
57 F
Function: Moderate
Distress: Low
I am: vg
I have:
Bipolar Disorder

See LadySirona's full Bupropion history

Mar 9, 2017 (Started Jul 01, 2010)

  • Effectiveness
    Major (for Persistent depressive disorder (dysthymia))
  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I poured into pill boxes and took them the same time daily
Cost: < $25 monthly

  • 0 helpful marks
zoomer
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zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: g
I have:
Bipolar I

See zoomer's full Bupropion history

Feb 6, 2017 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines. I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking Wellbutrin. I don't allocate all credit to this med. I take Trintellix also.I have noticed a more consistent level of lower anxiety on Wellbutrin.
Cost: < $25 monthly

Nov 29, 2015 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Just wanting to update. I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines.
Cost: < $25 monthly

Apr 6, 2011 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking wellbutrin. I don't allocate all credit to this med. I take Pristiq also. So, did it help me quit smoking? not yet.
Cost: < $25 monthly

Oct 25, 2010 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have noticed a more consistent level of lower anxiety on Wellbutrin. It has also noticeably helped decrease the depression a degree during episodes. I have also decreased my tabacco intake since taking .
Cost: < $25 monthly

  • 1 helpful mark
CupcakeKitten
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CupcakeKitten
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 0
External Stress: Severe
25 F
Function: Moderate
Distress: Low
I am: g
I have:
Borderline Personality

See CupcakeKitten's full Bupropion history

Jan 13, 2017 (Started Dec 06, 2016)

  • Effectiveness
    Slight (for Lack of motivation)
  • Effectiveness
    Slight (for Exhaustion)
  • Effectiveness
    Slight (for Excessive sleeping (hypersomnia))
  • Side effects
    Moderate (Muscle twitching (fasciculations), Impulsive behaviors)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion