What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,300 1,296
Depressed mood 1,619 803
Persistent depressive disorder (dysthymia) 402 329
Mild depression 155 68
Anxious mood 121 67
Bipolar disorder 112 94

Show all 193 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 272
Moderate 379
Mild 616
None 1,144

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 107
Anxious mood 70
Weight gain 58
Insomnia 53
Headaches 48
Constipation 43

Show all 439 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 183
150 mg daily 150
100 mg daily 72
300 mg/24 hours daily 68
450 mg daily 53
75 mg daily 47
150 mg twice daily 37
100 mg twice daily 30
150 mg/24 hours daily 26
200 mg daily 25

See all 64 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 661
Side effects too severe 555
Doctor's advice 428
Other 279
Course of treatment ended 92
Expense 84
Personal research 72
Change in health plan coverage 44
See all 1612 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 9
1 - 6 months 35
6 months - 1 year 85
1 - 2 years 119
2 - 5 years 220
5 - 10 years 200
10 years or more 167

Stopped taking Bupropion

Duration Patients
Less than 1 month 356
1 - 6 months 357
6 months - 1 year 236
1 - 2 years 229
2 - 5 years 283
5 - 10 years 127
10 years or more 63
Adherence
Adherence Evaluations
Always 1892
Usually 355
Sometimes 51
Never taken as prescribed 113
Burden
Burden Evaluations
Very hard to take 81
Somewhat hard to take 146
A little hard to take 341
Not at all hard to take 1843
Cost per month
Cost per month Evaluations
$200+ 15
$100-199 26
$50-99 86
$25-49 175
< $25 1161
Not specified 948

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 94
Fluoxetine (Prozac) 90
Venlafaxine (Effexor XR) 73
Citalopram (Celexa) 52
Duloxetine (Cymbalta) 48

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 37
Citalopram (Celexa) 32
Fluoxetine (Prozac) 31

Show all 49 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Apr 11, 2018 (Started May 15, 2017)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Cost: $200+ monthly

  • 0 helpful marks

Jan 12, 2018 (Started Jun 30, 2017)

  • Effectiveness
    Moderate (for chronic fatigue)
  • Side effects
    Severe (vomiting, nausea)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Dec 15, 2017 (Started Jun 01, 2006)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Severe (insomnia, hot flashes, feeling tense or on edge, feeling feverish, facial flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: If you are taking the generic extended release make sure it is not dose dumping - releasing too much medicine at once causing side effects. My MS doctor, PCP, and I thought I was in menopause with all the hot flashes and fevers of 99.6! Even kept going in to see if I had a UTI bc of the fevers! What a waste of my time and money!!!
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion