What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Wellbutrin SR Show all

false

Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,845 1,065
Depressed mood 1,519 722
Persistent depressive disorder (dysthymia) 340 285
Mild Depression 139 56
Anxious mood 114 55
Bipolar Disorder 102 85

Show all 207 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 233
Moderate 333
Mild 549
None 956

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 93
Anxious mood 56
Weight gain 49
Insomnia 46
Headaches 42
Constipation 41

Show all 417 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 139
150 mg daily 129
100 mg daily 82
300 mg/24 hours daily 72
450 mg daily 46
75 mg daily 44
100 mg twice daily 38
150 mg/24 hours daily 28
150 mg twice daily 26
200 mg daily 25

See all 71 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 564
Side effects too severe 481
Doctor's advice 372
Other 250
Course of treatment ended 81
Expense 78
Personal research 67
Change in health plan coverage 36
See all 1391 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 6
1 - 6 months 62
6 months - 1 year 81
1 - 2 years 130
2 - 5 years 181
5 - 10 years 182
10 years or more 129

Stopped taking Bupropion

Duration Patients
Less than 1 month 278
1 - 6 months 330
6 months - 1 year 221
1 - 2 years 204
2 - 5 years 242
5 - 10 years 110
10 years or more 47
Adherence
Adherence Evaluations
Always 1616
Usually 321
Sometimes 45
Never taken as prescribed 89
Burden
Burden Evaluations
Very hard to take 69
Somewhat hard to take 128
A little hard to take 314
Not at all hard to take 1560
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 26
$50-99 78
$25-49 158
< $25 1009
Not specified 790

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 66
Fluoxetine (Prozac) 56
Venlafaxine (Effexor XR) 53
Duloxetine (Cymbalta) 38
Citalopram (Celexa) 31

Show all 39 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 39
Sertraline (Zoloft) 31
Venlafaxine (Effexor XR) 24
Fluoxetine (Prozac) 20
Escitalopram (Lexapro) 19

Show all 40 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,580 members have decided to share their profiles only with other members of PatientsLikeMe.

LadySirona
97627 thumb
LadySirona
Gender: F
Data Quality: 2 stars
Depression: 2
Mania: 1
Emotional: 1
Anxiety: 2
Compulsion: 2
External Stress: Overwhelming
57 F
Function: Moderate
Distress: Low
I am: vg
I have:
Bipolar Disorder

See LadySirona's full Bupropion history

Mar 9, 2017 (Started Jul 01, 2010)

  • Effectiveness
    Major (for Persistent depressive disorder (dysthymia))
  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I poured into pill boxes and took them the same time daily
Cost: < $25 monthly

  • 0 helpful marks
zoomer
60535 thumb
zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: g
I have:
Bipolar I

See zoomer's full Bupropion history

Feb 6, 2017 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines. I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking Wellbutrin. I don't allocate all credit to this med. I take Trintellix also.I have noticed a more consistent level of lower anxiety on Wellbutrin.
Cost: < $25 monthly

Nov 29, 2015 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Just wanting to update. I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines.
Cost: < $25 monthly

Apr 6, 2011 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking wellbutrin. I don't allocate all credit to this med. I take Pristiq also. So, did it help me quit smoking? not yet.
Cost: < $25 monthly

Oct 25, 2010 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have noticed a more consistent level of lower anxiety on Wellbutrin. It has also noticeably helped decrease the depression a degree during episodes. I have also decreased my tabacco intake since taking .
Cost: < $25 monthly

  • 1 helpful mark
CupcakeKitten
76997 thumb
CupcakeKitten
Gender: F
Data Quality: 3 stars
Depression: 2
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 1
External Stress: Moderate
25 F
Function: Moderate
Distress: Low
I am: g
I have:
Borderline Personality

See CupcakeKitten's full Bupropion history

Jan 13, 2017 (Started Dec 06, 2016)

  • Effectiveness
    Slight (for Lack of motivation)
  • Effectiveness
    Slight (for Exhaustion)
  • Effectiveness
    Slight (for Excessive sleeping (hypersomnia))
  • Side effects
    Moderate (Muscle twitching (fasciculations), Impulsive behaviors)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion