What is Carbidopa-Levodopa CR?

Category: Prescription Drugs

Most popular types: Sinemet CR Half Sinemet CR Carbilev Show all

false

A controlled release preparation of carbidopa/levodopa formulated to release a lower, smoother dose of medication. It is sometimes taken last thing at night in order to maintain dopamine levels throughout sleep and into the morning.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's Disease 293 146
Stiffness/Spasticity 33 14
Improve mobility 13 8
Sleep problems 6 2
Insomnia 5 4
Slowness 5 1

Show all 44 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 9
Moderate 26
Mild 35
None 105

Commonly reported side effects and conditions associated with Carbidopa-Levodopa CR

Side effect Patients
Dyskinesia 9
Vivid dreams 9
Fatigue 8
Nausea 7
Back pain 4
Urine amber color 4

Show all 42 reported side effects

Dosages

Based on patients currently taking Carbidopa-Levodopa CR

Dosage Patients
50 mg-200 mg daily 11
25 mg-100 mg daily 7
50-200 mg daily 2
2 x 50 mg-200 mg daily 2
1.5 capsule(s) daily 1
25-100 mg twice daily 1
2 x 25-100 mg daily 1
25-100 mg three times daily 1
50-200 mg twice daily 1
2 x 25 mg-100 mg daily 1

See all 26 dosages

Why patients stopped taking Carbidopa-Levodopa CR

Multiple reasons could be selected

Reason Patients
Doctor's advice 35
Did not seem to work 19
Other 15
Side effects too severe 13
Personal research 5
Course of treatment ended 2
Change in health plan coverage 1
Expense 1
See all 77 patients who’ve stopped taking Carbidopa-Levodopa CR

Duration

Currently taking Carbidopa-Levodopa CR

Duration Patients
1 - 6 months 1
6 months - 1 year 4
1 - 2 years 5
2 - 5 years 16
5 - 10 years 15
10 years or more 4

Stopped taking Carbidopa-Levodopa CR

Duration Patients
Less than 1 month 7
1 - 6 months 21
6 months - 1 year 6
1 - 2 years 18
2 - 5 years 15
5 - 10 years 8
10 years or more 3
Adherence
Adherence Evaluations
Always 129
Usually 34
Sometimes 5
Never taken as prescribed 7
Burden
Burden Evaluations
Very hard to take 7
Somewhat hard to take 16
A little hard to take 54
Not at all hard to take 98
Cost per month
Cost per month Evaluations
$200+ 5
$100-199 4
$50-99 6
$25-49 6
< $25 90
Not specified 64

What people switch to and from

Patients started taking Carbidopa-Levodopa CR after stopping:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 5
Carbidopa-Entacapone-Levodopa (Stalevo) 2
Carbidopa Levodopa ER (Rytary XR) 2
Apomorphine (Apokyn) 1
Entacapone (Comtan) 1

Show all 6 treatments patients report switching from

Patients stopped taking Carbidopa-Levodopa CR and switched to:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 6
Carbidopa Levodopa ER (Rytary XR) 4
Apomorphine (Apokyn) 1
Levodopa-Benserazide (Madopar) 1
Rasagiline (Azilect) 1
Last updated:

31 patient evaluations for Carbidopa-Levodopa CR

104 members have decided to share their profiles only with other members of PatientsLikeMe.

margie99
70573 thumb
margie99
Sex: F
Data Quality: 3 stars
On
Mouth/throat: mild
Arms: mild
Chest: mild
Legs: moderate
I am: g
I have:
Parkinson's

See margie99's full Carbidopa-Levodopa CR history

Oct 10, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Mild (Breakthrough pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: At times my legs and feet cramp and I use the tens unit during the night.
Cost: < $25 monthly

Sep 14, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    Mild (Breakthrough pain)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: No change
Cost: < $25 monthly

Jul 13, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Mild (Breakthrough pain)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: I have breakthrough pain at times, but twisting and curling does not happen until 1 to 2 weeks before the next injections.
Cost: < $25 monthly

Nov 18, 2015 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    Mild (Breakthrough pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: Get up and use Tens unit to help
Cost: < $25 monthly

Sep 16, 2015 (Started Jul 01, 2011)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Cost: < $25 monthly

Jul 15, 2015 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
PDWarrior
1274 thumb
PDWarrior
Sex: M
Data Quality: 0 stars
Mouth/throat: mild
Arms: mild
Chest: mild
Legs: mild
I have:
Parkinson's

See PDWarrior's full Carbidopa-Levodopa CR history

Feb 6, 2016 (Started Jul 09, 2008)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 4 x 25 mg-100 mg Daily
Cost: < $25 monthly

Jan 12, 2009 (Started Jul 09, 2008)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Christina22222
Portrait default thumb
Christina22222
Data Quality: 3 stars
  • Gender: F
  • Age: 45
Condition: TBI 2 additional condition(s)
Quality of life:
  • Mental: None
  • Physical: None
I am: vg
I have:
TBI

See Christina22222's full Carbidopa-Levodopa CR history

Jan 15, 2016 (Started Oct 06, 2008)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: It was helpful at bedtime. I slept sounder on Carbidopa-Levodopa CR.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 31 patient evaluations for Carbidopa-Levodopa CR