What is Carbidopa-Levodopa?

Category: Prescription Drugs

Most popular types: Sinemet Carbidopa-Levodopa 25-100 Sinemet 25/100 Show all

false

Levodopa is a dopamine precursor used to treat the movement disorder symptoms of Parkinson's disease. Carbidopa is often included with levodopa-containing drugs in order to boost its efficacy by slowing down the metabolism of dopamine.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's Disease 2,431 1,417
Stiffness/Spasticity 111 71
MSA (Multiple System Atrophy) 76 51
RLS (Restless Legs Syndrome) 66 40
Tremor(s) 58 56
Slowness 48 32

Show all 98 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 71
Moderate 309
Mild 481
None 663

Commonly reported side effects and conditions associated with Carbidopa-Levodopa

Side effect Patients
Dyskinesia 124
Nausea 115
Drowsiness 43
Jerky movements (dyskinesia) 26
Stomach upset 24
Headaches 21

Show all 300 reported side effects

Dosages

Based on patients currently taking Carbidopa-Levodopa

Dosage Patients
25 mg-100 mg three times daily 45
25-100 mg three times daily 40
3 x 25 mg-100 mg daily 34
25-100 mg four times daily 20
25 mg-100 mg four times daily 20
4 x 25 mg-100 mg daily 20
2 x 25-100 mg three times daily 16
6 x 25 mg-100 mg daily 16
25 mg-100 mg daily 14
2 x 25-100 mg four times daily 14

See all 171 dosages

Why patients stopped taking Carbidopa-Levodopa

Multiple reasons could be selected

Reason Patients
Doctor's advice 123
Did not seem to work 94
Side effects too severe 77
Other 70
Personal research 27
Course of treatment ended 19
Change in health plan coverage 7
Expense 5
See all 336 patients who’ve stopped taking Carbidopa-Levodopa

Duration

Currently taking Carbidopa-Levodopa

Duration Patients
Less than 1 month 2
1 - 6 months 30
6 months - 1 year 34
1 - 2 years 84
2 - 5 years 190
5 - 10 years 194
10 years or more 63

Stopped taking Carbidopa-Levodopa

Duration Patients
Less than 1 month 36
1 - 6 months 81
6 months - 1 year 55
1 - 2 years 58
2 - 5 years 81
5 - 10 years 37
10 years or more 5
Adherence
Adherence Evaluations
Always 1111
Usually 335
Sometimes 38
Never taken as prescribed 40
Burden
Burden Evaluations
Very hard to take 53
Somewhat hard to take 256
A little hard to take 383
Not at all hard to take 832
Cost per month
Cost per month Evaluations
$200+ 11
$100-199 19
$50-99 59
$25-49 137
< $25 843
Not specified 455

What people switch to and from

Patients started taking Carbidopa-Levodopa after stopping:

Treatment Patients
Ropinirole (Requip) 32
Pramipexole (Mirapex) 22
Carbidopa-Entacapone-Levodopa (Stalevo) 15
Rasagiline (Azilect) 15
Amantadine (Symmetrel) 12

Show all 16 treatments patients report switching from

Patients stopped taking Carbidopa-Levodopa and switched to:

Treatment Patients
Carbidopa Levodopa ER (Rytary XR) 39
Carbidopa-Entacapone-Levodopa (Stalevo) 10
Carbidopa-Levodopa CR (Sinemet CR) 6
Ropinirole (Requip) 6
Carbidopa-Levodopa (Sinemet) 5

Show all 16 treatments patients report switching to

Last updated:

126 patient evaluations for Carbidopa-Levodopa

963 members have decided to share their profiles only with other members of PatientsLikeMe.

princess adventurous
Portrait default thumb
princess adventurous
Sex: F
Data Quality: 0 stars
On
Mouth/throat: mild
Arms: mild
Chest: mild
Legs: mild
I am: g
I have:
Parkinson's

See princess adventurous's full Carbidopa-Levodopa history

Feb 14, 2014 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: $50-99 monthly

  • 0 helpful marks
cwright7
48962 thumb
cwright7
Sex: M
Data Quality: 1 star
Mood: Very bad
Cognition: Severe
Autonomic: Severe
Head: moderate
Arms: severe
Legs: severe
Tremors: severe
I am: b
I have:
MSA

See cwright7's full Carbidopa-Levodopa history

Jan 15, 2014 (Started Apr 20, 2011)

  • Effectiveness
    None (for MSA (Multiple System Atrophy))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 6 x 25 mg-100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
parkinohio
Portrait default thumb
parkinohio
Sex: M
Data Quality: 0 stars
On
Mouth/throat: mild
Arms: mild
Chest: mild
Legs: mild
I am: g
I have:
Parkinson's

See parkinohio's full Carbidopa-Levodopa history

Oct 22, 2013 (Started Nov 15, 2005)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 6 x 25 mg-250 mg Daily
Cost: $25-49 monthly

Jan 18, 2013 (Started Nov 15, 2005)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 6 x 25 mg-250 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 126 patient evaluations for Carbidopa-Levodopa