What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,315 1,310
Depressed mood 1,621 809
Persistent depressive disorder (dysthymia) 407 334
Mild depression 155 69
Anxious mood 121 66
Bipolar disorder 112 95

Show all 192 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 277
Moderate 380
Mild 622
None 1,153

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 108
Anxious mood 70
Weight gain 58
Insomnia 53
Headaches 48
Constipation 43

Show all 377 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 170
150 mg daily 132
300 mg/24 hours daily 63
100 mg daily 60
450 mg daily 54
75 mg daily 43
150 mg twice daily 38
100 mg twice daily 27
200 mg daily 26
150 mg/24 hours daily 24

See all 60 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 663
Side effects too severe 560
Doctor's advice 436
Other 279
Course of treatment ended 94
Expense 85
Personal research 73
Change in health plan coverage 44
See all 1626 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 4
1 - 6 months 38
6 months - 1 year 42
1 - 2 years 109
2 - 5 years 206
5 - 10 years 193
10 years or more 174

Stopped taking Bupropion

Duration Patients
Less than 1 month 359
1 - 6 months 358
6 months - 1 year 236
1 - 2 years 233
2 - 5 years 286
5 - 10 years 128
10 years or more 64
Adherence
Adherence Evaluations
Always 1906
Usually 360
Sometimes 51
Never taken as prescribed 115
Burden
Burden Evaluations
Very hard to take 83
Somewhat hard to take 146
A little hard to take 343
Not at all hard to take 1860
Cost per month
Cost per month Evaluations
$200+ 16
$100-199 27
$50-99 86
$25-49 175
< $25 1166
Not specified 962

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 95
Fluoxetine (Prozac) 92
Venlafaxine (Effexor XR) 73
Citalopram (Celexa) 54
Duloxetine (Cymbalta) 49

Show all 55 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 33
Fluoxetine (Prozac) 32

Show all 49 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Jul 1, 2007 (Started Jul 01, 2006)

  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily

  • 0 helpful marks

Mar 1, 2007 (Started Aug 19, 2006)

  • Effectiveness
    Moderate (for persistent depressive disorder (dysthymia))
  • Side effects
    Mild (weight loss)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: $25-49 monthly
Side effects: weight loss

  • 0 helpful marks

Dec 15, 2006 (Started Dec 15, 2005)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (excessive sweating, agitation, elevated blood pressure, constipation)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 75 mg Daily
Advice & Tips: If you are the type of person where you are a bit nervous naturally, on edge, then this anti-depressant is not the right choice for you. It is very popular as it works with dopamine, but for me it didn't help me as much as it made me constantly nervous, and I would go through extreme sweating from time to time especially a couple hours after I would take it. As I reflect back, I would get a lot of anxiousness, and had a hard time being in groups, which was never a problem prior.
Cost: $25-49 monthly
Side effects: constipation, elevated blood pressure, agitation, excessive sweating, elevated blood pressure, agitation, excessive sweating

  • 1 helpful mark
Last updated:
Showing 3 of 188 patient evaluations for Bupropion