What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,276 1,287
Depressed mood 1,611 795
Persistent depressive disorder (dysthymia) 397 324
Mild depression 154 65
Anxious mood 122 65

Show all 195 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
272
Moderate
378
Mild
612
None
1,127

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 106
Anxious mood 71
Weight gain 57
Insomnia 50
Headaches 48
Constipation 43

Show all 446 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 183
150 mg daily 144
100 mg daily 73
300 mg/24 hours daily 65
450 mg daily 57
75 mg daily 49
150 mg twice daily 36
200 mg daily 31
100 mg twice daily 29
150 mg/24 hours daily 27

See all 74 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 656
Side effects too severe 553
Doctor's advice 426
Other 276
Course of treatment ended 91
Expense 81
Personal research 71
Change in health plan coverage 43
See all 1597 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 4
1 - 6 months 50
6 months - 1 year 100
1 - 2 years 110
2 - 5 years 221
5 - 10 years 193
10 years or more 170

Stopped taking Bupropion

Duration Patients
Less than 1 month 354
1 - 6 months 356
6 months - 1 year 232
1 - 2 years 229
2 - 5 years 280
5 - 10 years 124
10 years or more 60
Adherence
Adherence Evaluations
Always 1868
Usually 356
Sometimes 54
Never taken as prescribed 111
Burden
Burden Evaluations
Very hard to take 83
Somewhat hard to take 147
A little hard to take 341
Not at all hard to take 1818
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 26
$50-99 86
$25-49 174
< $25 1154
Not specified 936

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 96
Fluoxetine (Prozac) 89
Venlafaxine (Effexor XR) 72
Citalopram (Celexa) 53
Duloxetine (Cymbalta) 48

Show all 57 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 50
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 32
Fluoxetine (Prozac) 31

Show all 47 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks

Apr 15, 2017 (Started Jan 15, 2014)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I was told I would probably lose weight on this, but I didn't.
Cost: $25-49 monthly

Sep 15, 2014 (Started Jan 15, 2014)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Mar 9, 2017 (Started Jul 01, 2010)

  • Effectiveness
    Major (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I poured into pill boxes and took them the same time daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion