What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,229 1,261
Depressed mood 1,594 782
Persistent depressive disorder (dysthymia) 387 316
Mild depression 152 65
Anxious mood 121 64

Show all 193 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
263
Moderate
374
Mild
604
None
1,102

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 104
Anxious mood 69
Weight gain 55
Insomnia 50
Headaches 47
Constipation 43

Show all 441 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 183
150 mg daily 138
100 mg daily 80
300 mg/24 hours daily 62
450 mg daily 53
75 mg daily 41
150 mg twice daily 33
100 mg twice daily 30
150 mg/24 hours daily 26
200 mg daily 26

See all 72 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 642
Side effects too severe 540
Doctor's advice 415
Other 272
Course of treatment ended 88
Expense 82
Personal research 70
Change in health plan coverage 42
See all 1565 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 4
1 - 6 months 80
6 months - 1 year 77
1 - 2 years 107
2 - 5 years 199
5 - 10 years 184
10 years or more 171

Stopped taking Bupropion

Duration Patients
Less than 1 month 330
1 - 6 months 354
6 months - 1 year 244
1 - 2 years 225
2 - 5 years 272
5 - 10 years 120
10 years or more 58
Adherence
Adherence Evaluations
Always 1829
Usually 352
Sometimes 54
Never taken as prescribed 108
Burden
Burden Evaluations
Very hard to take 78
Somewhat hard to take 147
A little hard to take 338
Not at all hard to take 1780
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 24
$50-99 85
$25-49 173
< $25 1131
Not specified 917

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 91
Fluoxetine (Prozac) 84
Venlafaxine (Effexor XR) 69
Citalopram (Celexa) 50
Duloxetine (Cymbalta) 48

Show all 55 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 46
Sertraline (Zoloft) 45
Venlafaxine (Effexor XR) 34
Citalopram (Celexa) 31
Fluoxetine (Prozac) 27

Show all 46 treatments patients report switching to

Last updated:

184 patient evaluations for Bupropion

Mar 9, 2017 (Started Jul 01, 2010)

  • Effectiveness
    Major (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I poured into pill boxes and took them the same time daily
Cost: < $25 monthly

  • 0 helpful marks

Feb 6, 2017 (Started Dec 04, 2009)

  • Effectiveness
    None (for tobacco use disorder)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines. I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking Wellbutrin. I don't allocate all credit to this med. I take Trintellix also.I have noticed a more consistent level of lower anxiety on Wellbutrin.
Cost: < $25 monthly

Nov 29, 2015 (Started Dec 04, 2009)

  • Effectiveness
    None (for tobacco use disorder)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Just wanting to update. I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines.
Cost: < $25 monthly

Apr 6, 2011 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking wellbutrin. I don't allocate all credit to this med. I take Pristiq also. So, did it help me quit smoking? not yet.
Cost: < $25 monthly

Oct 25, 2010 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have noticed a more consistent level of lower anxiety on Wellbutrin. It has also noticeably helped decrease the depression a degree during episodes. I have also decreased my tabacco intake since taking .
Cost: < $25 monthly

  • 1 helpful mark

Jan 13, 2017 (Started Dec 06, 2016)

  • Effectiveness
    Slight (for lack of motivation)
  • Effectiveness
    Slight (for exhaustion)
  • Effectiveness
    Slight (for excessive sleeping (hypersomnia))
  • Side effects
    Moderate (muscle twitching (fasciculations), impulsivity)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 184 patient evaluations for Bupropion