What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

false

Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,340 1,327
Depressed mood 1,631 812
Persistent depressive disorder (dysthymia) 409 337
Mild depression 155 69
Anxious mood 121 64

Show all 185 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 281
Moderate 388
Mild 631
None 1,156

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 110
Anxious mood 72
Weight gain 59
Insomnia 54
Headaches 48
Constipation 43

Show all 364 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 164
150 mg daily 120
100 mg daily 67
300 mg/24 hours daily 53
450 mg daily 51
75 mg daily 41
150 mg twice daily 39
100 mg twice daily 25
150 mg/24 hours daily 23
200 mg daily 16

See all 58 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 670
Side effects too severe 565
Doctor's advice 441
Other 282
Course of treatment ended 96
Expense 84
Personal research 73
Change in health plan coverage 45
See all 1642 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
1 - 6 months 33
6 months - 1 year 41
1 - 2 years 101
2 - 5 years 194
5 - 10 years 184
10 years or more 162

Stopped taking Bupropion

Duration Patients
Less than 1 month 362
1 - 6 months 365
6 months - 1 year 238
1 - 2 years 234
2 - 5 years 289
5 - 10 years 127
10 years or more 65
Adherence
Adherence Evaluations
Always 1927
Usually 362
Sometimes 51
Never taken as prescribed 116
Burden
Burden Evaluations
Very hard to take 84
Somewhat hard to take 149
A little hard to take 346
Not at all hard to take 1877
Cost per month
Cost per month Evaluations
$200+ 16
$100-199 27
$50-99 86
$25-49 178
< $25 1169
Not specified 980

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 95
Fluoxetine (Prozac) 94
Venlafaxine (Effexor XR) 74
Citalopram (Celexa) 55
Duloxetine (Cymbalta) 49

Show all 55 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 33
Escitalopram (Lexapro) 32

Show all 48 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Jul 1, 2017 (Started Jan 04, 2016)

  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 450 mg Daily

  • 0 helpful marks

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 200 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion