What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,311 1,302
Depressed mood 1,619 805
Persistent depressive disorder (dysthymia) 405 333
Mild depression 155 68
Anxious mood 121 67
Bipolar disorder 112 94

Show all 192 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 275
Moderate 379
Mild 620
None 1,145

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 108
Anxious mood 70
Weight gain 58
Insomnia 53
Headaches 48
Constipation 43

Show all 442 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 181
150 mg daily 135
100 mg daily 68
300 mg/24 hours daily 64
450 mg daily 50
75 mg daily 47
150 mg twice daily 38
100 mg twice daily 28
150 mg/24 hours daily 27
200 mg daily 23

See all 61 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 663
Side effects too severe 557
Doctor's advice 433
Other 278
Course of treatment ended 92
Expense 85
Personal research 73
Change in health plan coverage 44
See all 1620 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 3
1 - 6 months 38
6 months - 1 year 80
1 - 2 years 113
2 - 5 years 209
5 - 10 years 187
10 years or more 163

Stopped taking Bupropion

Duration Patients
Less than 1 month 358
1 - 6 months 357
6 months - 1 year 236
1 - 2 years 230
2 - 5 years 286
5 - 10 years 128
10 years or more 64
Adherence
Adherence Evaluations
Always 1899
Usually 356
Sometimes 51
Never taken as prescribed 113
Burden
Burden Evaluations
Very hard to take 83
Somewhat hard to take 146
A little hard to take 341
Not at all hard to take 1849
Cost per month
Cost per month Evaluations
$200+ 15
$100-199 27
$50-99 86
$25-49 175
< $25 1163
Not specified 953

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 96
Fluoxetine (Prozac) 91
Venlafaxine (Effexor XR) 75
Citalopram (Celexa) 54
Duloxetine (Cymbalta) 49

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 33
Fluoxetine (Prozac) 31

Show all 49 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 200 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion