What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,229 1,261
Depressed mood 1,594 782
Persistent depressive disorder (dysthymia) 387 316
Mild depression 152 65
Anxious mood 121 64

Show all 193 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
263
Moderate
374
Mild
604
None
1,102

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 104
Anxious mood 69
Weight gain 55
Insomnia 50
Headaches 47
Constipation 43

Show all 441 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 183
150 mg daily 138
100 mg daily 80
300 mg/24 hours daily 62
450 mg daily 53
75 mg daily 41
150 mg twice daily 33
100 mg twice daily 30
150 mg/24 hours daily 26
200 mg daily 26

See all 72 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 642
Side effects too severe 540
Doctor's advice 415
Other 272
Course of treatment ended 88
Expense 82
Personal research 70
Change in health plan coverage 42
See all 1565 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 4
1 - 6 months 80
6 months - 1 year 77
1 - 2 years 107
2 - 5 years 199
5 - 10 years 184
10 years or more 171

Stopped taking Bupropion

Duration Patients
Less than 1 month 330
1 - 6 months 354
6 months - 1 year 244
1 - 2 years 225
2 - 5 years 272
5 - 10 years 120
10 years or more 58
Adherence
Adherence Evaluations
Always 1829
Usually 352
Sometimes 54
Never taken as prescribed 108
Burden
Burden Evaluations
Very hard to take 78
Somewhat hard to take 147
A little hard to take 338
Not at all hard to take 1780
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 24
$50-99 85
$25-49 173
< $25 1131
Not specified 917

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 91
Fluoxetine (Prozac) 84
Venlafaxine (Effexor XR) 69
Citalopram (Celexa) 50
Duloxetine (Cymbalta) 48

Show all 55 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 46
Sertraline (Zoloft) 45
Venlafaxine (Effexor XR) 34
Citalopram (Celexa) 31
Fluoxetine (Prozac) 27

Show all 46 treatments patients report switching to

Last updated:

184 patient evaluations for Bupropion

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks

Apr 15, 2017 (Started Jan 15, 2014)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I was told I would probably lose weight on this, but I didn't.
Cost: $25-49 monthly

Sep 15, 2014 (Started Jan 15, 2014)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 184 patient evaluations for Bupropion