What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,276 1,288
Depressed mood 1,611 794
Persistent depressive disorder (dysthymia) 398 326
Mild depression 154 65
Anxious mood 122 65

Show all 195 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
272
Moderate
377
Mild
614
None
1,126

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 106
Anxious mood 71
Weight gain 57
Insomnia 50
Headaches 48
Constipation 43

Show all 447 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 191
150 mg daily 142
100 mg daily 72
300 mg/24 hours daily 65
450 mg daily 55
75 mg daily 53
150 mg twice daily 36
200 mg daily 32
100 mg twice daily 29
150 mg/24 hours daily 28

See all 73 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 655
Side effects too severe 553
Doctor's advice 425
Other 275
Course of treatment ended 91
Expense 81
Personal research 71
Change in health plan coverage 43
See all 1596 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 7
1 - 6 months 48
6 months - 1 year 100
1 - 2 years 114
2 - 5 years 223
5 - 10 years 192
10 years or more 170

Stopped taking Bupropion

Duration Patients
Less than 1 month 354
1 - 6 months 356
6 months - 1 year 232
1 - 2 years 227
2 - 5 years 280
5 - 10 years 124
10 years or more 60
Adherence
Adherence Evaluations
Always 1868
Usually 356
Sometimes 54
Never taken as prescribed 111
Burden
Burden Evaluations
Very hard to take 83
Somewhat hard to take 147
A little hard to take 341
Not at all hard to take 1818
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 26
$50-99 86
$25-49 174
< $25 1154
Not specified 936

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 96
Fluoxetine (Prozac) 89
Venlafaxine (Effexor XR) 72
Citalopram (Celexa) 53
Duloxetine (Cymbalta) 48

Show all 57 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 50
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 32
Escitalopram (Lexapro) 30

Show all 47 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

Sep 19, 2017 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Mild (headaches)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 300 mg Daily
Cost: < $25 monthly

Sep 17, 2012 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (headaches)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Advice & Tips: Have someone you trust remind you to take the medicines. I have my wife who reminds me, although I have the medicine in the cupboard by the glasses. When I experience headaches with the buproprion, I take some Aleve or Motrin.
Cost: < $25 monthly

  • 0 helpful marks

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion