What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,300 1,296
Depressed mood 1,619 804
Persistent depressive disorder (dysthymia) 401 330
Mild depression 155 68
Anxious mood 121 67
Bipolar disorder 112 94

Show all 193 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 273
Moderate 379
Mild 616
None 1,145

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 107
Anxious mood 70
Weight gain 58
Insomnia 53
Headaches 48
Constipation 43

Show all 440 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 180
150 mg daily 149
100 mg daily 72
300 mg/24 hours daily 68
450 mg daily 55
75 mg daily 47
150 mg twice daily 39
200 mg daily 28
150 mg/24 hours daily 26
100 mg twice daily 25

See all 65 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 660
Side effects too severe 556
Doctor's advice 428
Other 279
Course of treatment ended 92
Expense 84
Personal research 72
Change in health plan coverage 44
See all 1612 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 8
1 - 6 months 35
6 months - 1 year 85
1 - 2 years 120
2 - 5 years 217
5 - 10 years 197
10 years or more 171

Stopped taking Bupropion

Duration Patients
Less than 1 month 357
1 - 6 months 357
6 months - 1 year 235
1 - 2 years 229
2 - 5 years 283
5 - 10 years 127
10 years or more 63
Adherence
Adherence Evaluations
Always 1894
Usually 355
Sometimes 51
Never taken as prescribed 113
Burden
Burden Evaluations
Very hard to take 82
Somewhat hard to take 146
A little hard to take 341
Not at all hard to take 1844
Cost per month
Cost per month Evaluations
$200+ 15
$100-199 27
$50-99 86
$25-49 175
< $25 1162
Not specified 948

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 94
Fluoxetine (Prozac) 91
Venlafaxine (Effexor XR) 73
Citalopram (Celexa) 52
Duloxetine (Cymbalta) 48

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 32
Fluoxetine (Prozac) 31

Show all 49 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Dec 1, 2017 (Started Jul 01, 2007)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Cost: $50-99 monthly

Apr 8, 2012 (Started Jul 01, 2007)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (morning nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: I use a pill organizer to keep track of whether or not I have taken my pills for the day and take them at the same time every day. I take pills at night when possible to minimize nausea.
Cost: $100-199 monthly

  • 0 helpful marks

Sep 19, 2017 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Mild (headaches)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Sep 17, 2012 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (headaches)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Advice & Tips: Have someone you trust remind you to take the medicines. I have my wife who reminds me, although I have the medicine in the cupboard by the glasses. When I experience headaches with the buproprion, I take some Aleve or Motrin.
Cost: < $25 monthly

  • 1 helpful mark

Jul 1, 2017 (Started Jan 04, 2016)

  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 450 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion