What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 2,005 1,159
Depressed mood 1,543 741
Persistent depressive disorder (dysthymia) 357 296
Mild Depression 144 59
Anxious mood 116 58
Bipolar Disorder 105 90

Show all 209 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 244
Moderate 354
Mild 576
None 1,024

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 101
Anxious mood 60
Weight gain 53
Insomnia 49
Headaches 48
Constipation 41

Show all 426 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 161
150 mg daily 148
100 mg daily 99
300 mg/24 hours daily 70
75 mg daily 56
450 mg daily 49
100 mg twice daily 46
150 mg twice daily 38
200 mg daily 30
150 mg/24 hours daily 26

See all 82 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 599
Side effects too severe 500
Doctor's advice 386
Other 261
Course of treatment ended 84
Expense 81
Personal research 69
Change in health plan coverage 39
See all 1463 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 10
1 - 6 months 87
6 months - 1 year 103
1 - 2 years 150
2 - 5 years 197
5 - 10 years 193
10 years or more 160

Stopped taking Bupropion

Duration Patients
Less than 1 month 297
1 - 6 months 343
6 months - 1 year 236
1 - 2 years 209
2 - 5 years 252
5 - 10 years 113
10 years or more 53
Adherence
Adherence Evaluations
Always 1714
Usually 336
Sometimes 48
Never taken as prescribed 100
Burden
Burden Evaluations
Very hard to take 74
Somewhat hard to take 140
A little hard to take 328
Not at all hard to take 1656
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 83
$25-49 163
< $25 1064
Not specified 850

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 77
Fluoxetine (Prozac) 69
Venlafaxine (Effexor XR) 59
Citalopram (Celexa) 41
Duloxetine (Cymbalta) 40

Show all 50 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 43
Sertraline (Zoloft) 38
Venlafaxine (Effexor XR) 28
Citalopram (Celexa) 22
Fluoxetine (Prozac) 22

Show all 42 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,691 members have decided to share their profiles only with other members of PatientsLikeMe.

jackconrad
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jackconrad
Sex: M
Data Quality: 1 star
Bulbar: none
Arms: moderate
Chest: none
Legs: moderate
I am: g
I have:
ALS

See jackconrad's full Bupropion history

Aug 15, 2016 (Started Aug 12, 2016)

  • Effectiveness
    None (for Mild Depression)
  • Side effects
    Severe (Tiredness increased)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 75 mg Daily
Advice & Tips: wiped me out..
Cost: < $25 monthly

Aug 7, 2016 (Started Aug 12, 2016)

  • Effectiveness
    None (for Mild Depression)
  • Side effects
    Severe
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Advice & Tips: find better..
Cost: < $25 monthly

  • 0 helpful marks
leejon66
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leejon66
Gender: M
Data Quality: 3 stars
Depression: 0
Mania: 0
Emotional: 1
Anxiety: 2
Compulsion: 0
External Stress: Low
68 M
Function: High
Distress: Low
I am: n
I have:
PTSD

See leejon66's full Bupropion history

Aug 5, 2016 (Started Jul 01, 1979)

  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg One time

Jun 5, 2015 (Started Jul 01, 1979)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: you need to talk to your Doctor about this treatment plan. some say it is to expense. I get my medIdecation from the VA

  • 0 helpful marks
jdlawrence
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jdlawrence
Gender: M
Data Quality: 1 star
Depression: 2
Mania: 1
Emotional: 1
Anxiety: 1
Compulsion: 1
External Stress: Moderate
28 M
Function: Moderate
Distress: Low
I am: vg
I have:
Major Depressive Disorder

See jdlawrence's full Bupropion history

Jun 28, 2016 (Started Aug 15, 2009)

  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: I took this exclusively for two years and found minimal effects. I'm now on Celexa, as well, and the combination is working, but I suspect it's really all the Celexa.

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion