What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
major depressive disorder 2,048 1,180
Depressed mood 1,551 748
persistent depressive disorder (dysthymia) 361 299
mild depression 146 60
Anxious mood 119 62
bipolar disorder 104 90

Show all 212 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 248
Moderate 360
Mild 582
None 1,037

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 101
Anxious mood 63
Weight gain 53
Insomnia 49
Headaches 48
Constipation 41

Show all 427 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 170
150 mg daily 155
100 mg daily 102
300 mg/24 hours daily 67
75 mg daily 62
450 mg daily 55
150 mg twice daily 43
100 mg twice daily 41
200 mg daily 32
150 mg/24 hours daily 23

See all 85 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 603
Side effects too severe 508
Doctor's advice 391
Other 264
Course of treatment ended 83
Expense 80
Personal research 71
Change in health plan coverage 39
See all 1480 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 8
1 - 6 months 94
6 months - 1 year 119
1 - 2 years 155
2 - 5 years 205
5 - 10 years 193
10 years or more 162

Stopped taking Bupropion

Duration Patients
Less than 1 month 302
1 - 6 months 344
6 months - 1 year 237
1 - 2 years 212
2 - 5 years 256
5 - 10 years 114
10 years or more 55
Adherence
Adherence Evaluations
Always 1739
Usually 338
Sometimes 48
Never taken as prescribed 102
Burden
Burden Evaluations
Very hard to take 75
Somewhat hard to take 140
A little hard to take 330
Not at all hard to take 1682
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 84
$25-49 166
< $25 1079
Not specified 860

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 81
Fluoxetine (Prozac) 74
Venlafaxine (Effexor XR) 60
Citalopram (Celexa) 42
Duloxetine (Cymbalta) 41

Show all 53 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 44
Sertraline (Zoloft) 40
Venlafaxine (Effexor XR) 28
Citalopram (Celexa) 25
Fluoxetine (Prozac) 23

Show all 43 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

leejon66
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leejon66
Gender: M
Data Quality: 2 stars
Depression: 0
Mania: 0
Emotional: 1
Anxiety: 3
Compulsion: 2
External Stress: Low
68 M
Function: High
Distress: Low
I am: b
I have:
PTSD

See leejon66's full Bupropion history

Aug 5, 2016 (Started Jul 01, 1979)

  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg One time

Jun 5, 2015 (Started Jul 01, 1979)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: you need to talk to your Doctor about this treatment plan. some say it is to expense. I get my medIdecation from the VA

  • 0 helpful marks
jdlawrence
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jdlawrence
Gender: M
Data Quality: 1 star
Depression: 2
Mania: 1
Emotional: 1
Anxiety: 1
Compulsion: 1
External Stress: Moderate
28 M
Function: Moderate
Distress: Low
I am: vg
I have:
Major Depressive Disorder

See jdlawrence's full Bupropion history

Jun 28, 2016 (Started Aug 15, 2009)

  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: I took this exclusively for two years and found minimal effects. I'm now on Celexa, as well, and the combination is working, but I suspect it's really all the Celexa.

  • 0 helpful marks
LittleBean
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LittleBean
Gender: F
Data Quality: 3 stars
Depression: 2
Mania: 0
Emotional: 1
Anxiety: 2
Compulsion: 0
External Stress: Moderate
32 F
Function: Moderate
Distress: Low
I am: g
I have:
ADD

See LittleBean's full Bupropion history

May 26, 2016 (Started Dec 22, 2013)

  • Effectiveness
    Slight (for Problems concentrating)
  • Effectiveness
    Moderate (for Lack of motivation)
  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Moderate (for attention deficit disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 450 mg Daily
Advice & Tips: More energy, less irritability.

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion