What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,112 1,210
Depressed mood 1,558 760
Persistent depressive disorder (dysthymia) 371 309
Mild depression 148 61
Anxious mood 121 66
Bipolar disorder 105 91

Show all 214 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 253
Moderate 367
Mild 588
None 1,059

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 102
Anxious mood 65
Weight gain 54
Insomnia 49
Headaches 47
Constipation 42

Show all 433 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 178
150 mg daily 157
100 mg daily 96
75 mg daily 59
300 mg/24 hours daily 57
450 mg daily 50
150 mg twice daily 42
100 mg twice daily 35
200 mg daily 28
150 mg/24 hours daily 20

See all 76 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 612
Side effects too severe 517
Doctor's advice 398
Other 265
Course of treatment ended 85
Expense 80
Personal research 71
Change in health plan coverage 40
See all 1501 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 2
1 - 6 months 83
6 months - 1 year 75
1 - 2 years 140
2 - 5 years 231
5 - 10 years 200
10 years or more 168

Stopped taking Bupropion

Duration Patients
Less than 1 month 310
1 - 6 months 346
6 months - 1 year 240
1 - 2 years 213
2 - 5 years 260
5 - 10 years 116
10 years or more 56
Adherence
Adherence Evaluations
Always 1771
Usually 344
Sometimes 49
Never taken as prescribed 103
Burden
Burden Evaluations
Very hard to take 76
Somewhat hard to take 141
A little hard to take 332
Not at all hard to take 1718
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 84
$25-49 168
< $25 1098
Not specified 879

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 86
Fluoxetine (Prozac) 78
Venlafaxine (Effexor XR) 61
Duloxetine (Cymbalta) 44
Citalopram (Celexa) 43

Show all 53 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 44
Sertraline (Zoloft) 42
Venlafaxine (Effexor XR) 30
Citalopram (Celexa) 27
Escitalopram (Lexapro) 24

Show all 44 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

Aug 5, 2016 (Started Jul 01, 1979)

  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg One time

Jun 5, 2015 (Started Jul 01, 1979)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: you need to talk to your Doctor about this treatment plan. some say it is to expense. I get my medIdecation from the VA

  • 0 helpful marks

Jun 28, 2016 (Started Aug 15, 2009)

  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: I took this exclusively for two years and found minimal effects. I'm now on Celexa, as well, and the combination is working, but I suspect it's really all the Celexa.

  • 0 helpful marks

May 26, 2016 (Started Dec 22, 2013)

  • Effectiveness
    Slight (for Problems concentrating)
  • Effectiveness
    Moderate (for Lack of motivation)
  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Moderate (for attention deficit disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 450 mg Daily
Advice & Tips: More energy, less irritability.

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion