What is Bupropion?

Category: Prescription Drugs

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,709 975
Depressed mood 1,498 710
Persistent depressive disorder (dysthymia) 326 277
Mild Depression 138 55
Anxious mood 114 54
Bipolar Disorder 100 84

Show all 205 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 221
Moderate 318
Mild 517
None 904

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 87
Anxious mood 53
Insomnia 45
Weight gain 45
Constipation 40
Headaches 38

Show all 399 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 114
300 mg daily 98
300 mg/24 hours daily 69
100 mg daily 62
450 mg daily 39
75 mg daily 35
100 mg twice daily 34
150 mg/24 hours daily 32
200 mg daily 25
150 mg twice daily 19

See all 66 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 538
Side effects too severe 460
Doctor's advice 357
Other 244
Course of treatment ended 77
Expense 77
Personal research 65
Change in health plan coverage 36
See all 1342 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 3
1 - 6 months 38
6 months - 1 year 60
1 - 2 years 103
2 - 5 years 156
5 - 10 years 171
10 years or more 116

Stopped taking Bupropion

Duration Patients
Less than 1 month 258
1 - 6 months 326
6 months - 1 year 212
1 - 2 years 198
2 - 5 years 236
5 - 10 years 106
10 years or more 46
Adherence
Adherence Evaluations
Always 1537
Usually 310
Sometimes 44
Never taken as prescribed 69
Burden
Burden Evaluations
Very hard to take 64
Somewhat hard to take 119
A little hard to take 299
Not at all hard to take 1478
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 25
$50-99 76
$25-49 154
< $25 953
Not specified 742

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 60
Fluoxetine (Prozac) 49
Venlafaxine (Effexor XR) 46
Duloxetine (Cymbalta) 35
Citalopram (Celexa) 26

Show all 38 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 36
Sertraline (Zoloft) 27
Venlafaxine (Effexor XR) 19
Citalopram (Celexa) 16
Escitalopram (Lexapro) 15

Show all 38 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

1,492 members have decided to share their profiles only with other members of PatientsLikeMe.

Missy180
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Missy180
Sex: F
Data Quality: 2 stars
Relapse: Mild
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: mild
Swallowing: mild
Upper limb: moderate
Walking: moderate
I am: g
I have:
MS

See Missy180's full Bupropion history

Apr 14, 2016 (Started Mar 16, 2016)

  • Effectiveness
    None (for Persistent depressive disorder (dysthymia))
  • Side effects
    Moderate (Pain in lower abdomen, Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: headaches never stopped, never benefited from the medication
Cost: < $25 monthly

Apr 5, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Pain in lower abdomen, Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Still having headaches.
Cost: < $25 monthly

Mar 26, 2016 (Started Mar 16, 2016)

  • Effectiveness
    None (for Persistent depressive disorder (dysthymia))
  • Side effects
    Moderate (Pain in lower abdomen, Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Two more days of headaches. Some stomach discomfort today also.
Cost: < $25 monthly

Mar 24, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: This is the third day I have experienced a horrible headache while on this medication. It usually starts about 1 1/2 hour after taking it. Today wasn't as bad as yesterdays. I hope they will subside.
Cost: < $25 monthly

Mar 23, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Severe (Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 22, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Moderate (Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 21, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Anxiety seems to still be more on the surface than prior to taking medication. Social anxiety, fast driving, lots of people, talking to people on the phone...
Cost: < $25 monthly

Mar 18, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I seem to get full faster therefore I am eating less than before beginning the medication.
Cost: < $25 monthly

Mar 17, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 16, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Anxious mood)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I had a very brief panic attack. It didn't last more than 30 seconds and then again it happened in the afternoon... again, very fleeting.
Cost: < $25 monthly

  • 0 helpful marks
stargeek
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stargeek
Gender: M
Data Quality: 1 star
Depression: 3
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 2
External Stress: Severe
47 M
Function: Moderate
Distress: Moderate
I am: b
I have:
Major Depressive Disorder

See stargeek's full Bupropion history

Dec 24, 2015 (Started Apr 11, 2013)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Cost: < $25 monthly

  • 0 helpful marks
John Jamson
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John Jamson
Gender: M
Data Quality: 1 star
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 1
External Stress: Severe
36 M
Function: High
Distress: Low
I am: n
I have:
Major Depressive Disorder

See John Jamson's full Bupropion history

Nov 13, 2015 (Started Sep 18, 2009)

  • Effectiveness
    Moderate (for Persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    None (for Fatigue)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Cost: $25-49 monthly

Oct 4, 2014 (Started Sep 18, 2009)

  • Effectiveness
    Moderate (for Fatigue)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion