What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Wellbutrin SR Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,840 1,058
Depressed mood 1,518 720
Persistent depressive disorder (dysthymia) 340 285
Mild Depression 139 56
Anxious mood 114 55
Bipolar Disorder 102 85

Show all 207 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 234
Moderate 333
Mild 547
None 948

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 93
Anxious mood 55
Weight gain 49
Insomnia 46
Headaches 42
Constipation 41

Show all 416 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 134
300 mg daily 132
100 mg daily 83
300 mg/24 hours daily 70
450 mg daily 47
75 mg daily 42
100 mg twice daily 39
150 mg/24 hours daily 30
200 mg daily 26
150 mg twice daily 25

See all 73 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 563
Side effects too severe 480
Doctor's advice 371
Other 250
Course of treatment ended 81
Expense 78
Personal research 67
Change in health plan coverage 36
See all 1389 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 8
1 - 6 months 56
6 months - 1 year 80
1 - 2 years 132
2 - 5 years 177
5 - 10 years 183
10 years or more 130

Stopped taking Bupropion

Duration Patients
Less than 1 month 277
1 - 6 months 330
6 months - 1 year 220
1 - 2 years 204
2 - 5 years 242
5 - 10 years 110
10 years or more 47
Adherence
Adherence Evaluations
Always 1609
Usually 321
Sometimes 45
Never taken as prescribed 87
Burden
Burden Evaluations
Very hard to take 69
Somewhat hard to take 127
A little hard to take 314
Not at all hard to take 1552
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 25
$50-99 78
$25-49 158
< $25 1003
Not specified 788

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 66
Fluoxetine (Prozac) 56
Venlafaxine (Effexor XR) 53
Duloxetine (Cymbalta) 38
Citalopram (Celexa) 31

Show all 39 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 39
Sertraline (Zoloft) 31
Venlafaxine (Effexor XR) 24
Citalopram (Celexa) 19
Escitalopram (Lexapro) 19

Show all 40 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,577 members have decided to share their profiles only with other members of PatientsLikeMe.

CupcakeKitten
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CupcakeKitten
Gender: F
Data Quality: 3 stars
Depression: 2
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 1
External Stress: Moderate
25 F
Function: Moderate
Distress: Low
I am: g
I have:
Borderline Personality

See CupcakeKitten's full Bupropion history

Apr 18, 2016 (Started Mar 29, 2016)

  • Effectiveness
    Moderate (for Slowness (bradykinesia))
  • Effectiveness
    Slight (for Problems concentrating)
  • Effectiveness
    Moderate (for Overwhelming fatigue)
  • Effectiveness
    None (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Fatigue)
  • Effectiveness
    Moderate (for Excessive sleeping (hypersomnia))
  • Effectiveness
    None (for Depressed mood)
  • Effectiveness
    Moderate (for Apathy)
  • Side effects
    Severe (Memory problems, Emotional sensitivity, Sensory sensitivity, Crying for no reason, Anxious mood, Panic attacks, Anger, Irritability, Heart palpitations)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg/24 hours Daily
Cost: < $25 monthly

  • 0 helpful marks
Missy180
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Missy180
Sex: F
Data Quality: 2 stars
Relapse: Mild
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: mild
Swallowing: mild
Upper limb: moderate
Walking: moderate
I am: g
I have:
MS

See Missy180's full Bupropion history

Apr 14, 2016 (Started Mar 16, 2016)

  • Effectiveness
    None (for Persistent depressive disorder (dysthymia))
  • Side effects
    Moderate (Pain in lower abdomen, Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: headaches never stopped, never benefited from the medication
Cost: < $25 monthly

Apr 5, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Pain in lower abdomen, Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Still having headaches.
Cost: < $25 monthly

Mar 26, 2016 (Started Mar 16, 2016)

  • Effectiveness
    None (for Persistent depressive disorder (dysthymia))
  • Side effects
    Moderate (Pain in lower abdomen, Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Two more days of headaches. Some stomach discomfort today also.
Cost: < $25 monthly

Mar 24, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: This is the third day I have experienced a horrible headache while on this medication. It usually starts about 1 1/2 hour after taking it. Today wasn't as bad as yesterdays. I hope they will subside.
Cost: < $25 monthly

Mar 23, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Severe (Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 22, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Moderate (Migraine headaches, Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 21, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Anxiety seems to still be more on the surface than prior to taking medication. Social anxiety, fast driving, lots of people, talking to people on the phone...
Cost: < $25 monthly

Mar 18, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I seem to get full faster therefore I am eating less than before beginning the medication.
Cost: < $25 monthly

Mar 17, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Anxious mood, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 16, 2016 (Started Mar 16, 2016)

  • Effectiveness
    Can’t tell (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Anxious mood)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I had a very brief panic attack. It didn't last more than 30 seconds and then again it happened in the afternoon... again, very fleeting.
Cost: < $25 monthly

  • 0 helpful marks
stargeek
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stargeek
Gender: M
Data Quality: 1 star
Depression: 3
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 2
External Stress: Severe
47 M
Function: Moderate
Distress: Moderate
I am: b
I have:
Major Depressive Disorder

See stargeek's full Bupropion history

Dec 24, 2015 (Started Apr 11, 2013)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion