What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,300 1,296
Depressed mood 1,617 802
Persistent depressive disorder (dysthymia) 402 329
Mild depression 155 68
Anxious mood 121 67
Bipolar disorder 112 94

Show all 193 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 272
Moderate 379
Mild 616
None 1,142

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 107
Anxious mood 70
Weight gain 58
Insomnia 52
Headaches 48
Constipation 43

Show all 441 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 188
150 mg daily 148
300 mg/24 hours daily 66
100 mg daily 62
450 mg daily 53
75 mg daily 50
150 mg twice daily 38
100 mg twice daily 30
200 mg daily 29
150 mg/24 hours daily 24

See all 67 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 659
Side effects too severe 556
Doctor's advice 427
Other 281
Course of treatment ended 92
Expense 85
Personal research 72
Change in health plan coverage 44
See all 1612 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 4
1 - 6 months 38
6 months - 1 year 95
1 - 2 years 114
2 - 5 years 226
5 - 10 years 193
10 years or more 166

Stopped taking Bupropion

Duration Patients
Less than 1 month 357
1 - 6 months 357
6 months - 1 year 234
1 - 2 years 231
2 - 5 years 282
5 - 10 years 127
10 years or more 64
Adherence
Adherence Evaluations
Always 1887
Usually 357
Sometimes 52
Never taken as prescribed 113
Burden
Burden Evaluations
Very hard to take 82
Somewhat hard to take 147
A little hard to take 341
Not at all hard to take 1839
Cost per month
Cost per month Evaluations
$200+ 15
$100-199 26
$50-99 86
$25-49 174
< $25 1162
Not specified 946

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 96
Fluoxetine (Prozac) 91
Venlafaxine (Effexor XR) 73
Citalopram (Celexa) 51
Duloxetine (Cymbalta) 48

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 50
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 32
Fluoxetine (Prozac) 31

Show all 48 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 200 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion