What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,212 1,256
Depressed mood 1,588 779
Persistent depressive disorder (dysthymia) 387 317
Mild depression 152 65
Anxious mood 122 67

Show all 192 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 263
Moderate 376
Mild 599
None 1,098

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 104
Anxious mood 69
Weight gain 55
Insomnia 49
Headaches 46
Constipation 43

Show all 439 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 159
150 mg daily 142
100 mg daily 84
300 mg/24 hours daily 56
450 mg daily 49
75 mg daily 47
150 mg twice daily 36
100 mg twice daily 32
200 mg daily 27
150 mg/24 hours daily 20

See all 65 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 638
Side effects too severe 539
Doctor's advice 413
Other 270
Course of treatment ended 88
Expense 81
Personal research 70
Change in health plan coverage 40
See all 1559 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 3
1 - 6 months 85
6 months - 1 year 69
1 - 2 years 108
2 - 5 years 190
5 - 10 years 179
10 years or more 159

Stopped taking Bupropion

Duration Patients
Less than 1 month 329
1 - 6 months 355
6 months - 1 year 243
1 - 2 years 225
2 - 5 years 269
5 - 10 years 120
10 years or more 57
Adherence
Adherence Evaluations
Always 1823
Usually 351
Sometimes 53
Never taken as prescribed 109
Burden
Burden Evaluations
Very hard to take 78
Somewhat hard to take 147
A little hard to take 334
Not at all hard to take 1777
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 24
$50-99 84
$25-49 170
< $25 1130
Not specified 915

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 90
Fluoxetine (Prozac) 83
Venlafaxine (Effexor XR) 65
Citalopram (Celexa) 49
Duloxetine (Cymbalta) 46

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 45
Sertraline (Zoloft) 45
Venlafaxine (Effexor XR) 33
Citalopram (Celexa) 30
Fluoxetine (Prozac) 27

Show all 45 treatments patients report switching to

Last updated:

184 patient evaluations for Bupropion

Feb 6, 2017 (Started Dec 04, 2009)

  • Effectiveness
    None (for tobacco use disorder)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines. I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking Wellbutrin. I don't allocate all credit to this med. I take Trintellix also.I have noticed a more consistent level of lower anxiety on Wellbutrin.
Cost: < $25 monthly

Nov 29, 2015 (Started Dec 04, 2009)

  • Effectiveness
    None (for tobacco use disorder)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Just wanting to update. I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines.
Cost: < $25 monthly

Apr 6, 2011 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking wellbutrin. I don't allocate all credit to this med. I take Pristiq also. So, did it help me quit smoking? not yet.
Cost: < $25 monthly

Oct 25, 2010 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have noticed a more consistent level of lower anxiety on Wellbutrin. It has also noticeably helped decrease the depression a degree during episodes. I have also decreased my tabacco intake since taking .
Cost: < $25 monthly

  • 1 helpful mark

Jan 13, 2017 (Started Dec 06, 2016)

  • Effectiveness
    Slight (for lack of motivation)
  • Effectiveness
    Slight (for exhaustion)
  • Effectiveness
    Slight (for excessive sleeping (hypersomnia))
  • Side effects
    Moderate (muscle twitching (fasciculations), impulsivity)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Nov 1, 2016 (Started Aug 19, 2016)

  • Effectiveness
    None (for persistent depressive disorder (dysthymia))
  • Side effects
    Severe (serotonin syndrome, night sweats, unrefreshing or poor sleep, constipation, shakiness, hot flashes, brain fog)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 184 patient evaluations for Bupropion