What is Bupropion?

Category: Prescription Drugs

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,709 975
Depressed mood 1,498 710
Persistent depressive disorder (dysthymia) 326 277
Mild Depression 138 55
Anxious mood 114 54
Bipolar Disorder 100 84

Show all 205 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 221
Moderate 318
Mild 517
None 904

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 87
Anxious mood 53
Insomnia 45
Weight gain 45
Constipation 40
Headaches 38

Show all 399 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 114
300 mg daily 98
300 mg/24 hours daily 69
100 mg daily 62
450 mg daily 39
75 mg daily 35
100 mg twice daily 34
150 mg/24 hours daily 32
200 mg daily 25
150 mg twice daily 19

See all 66 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 538
Side effects too severe 460
Doctor's advice 357
Other 244
Course of treatment ended 77
Expense 77
Personal research 65
Change in health plan coverage 36
See all 1342 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 3
1 - 6 months 38
6 months - 1 year 60
1 - 2 years 103
2 - 5 years 156
5 - 10 years 171
10 years or more 116

Stopped taking Bupropion

Duration Patients
Less than 1 month 258
1 - 6 months 326
6 months - 1 year 212
1 - 2 years 198
2 - 5 years 236
5 - 10 years 106
10 years or more 46
Adherence
Adherence Evaluations
Always 1537
Usually 310
Sometimes 44
Never taken as prescribed 69
Burden
Burden Evaluations
Very hard to take 64
Somewhat hard to take 119
A little hard to take 299
Not at all hard to take 1478
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 25
$50-99 76
$25-49 154
< $25 953
Not specified 742

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 60
Fluoxetine (Prozac) 49
Venlafaxine (Effexor XR) 46
Duloxetine (Cymbalta) 35
Citalopram (Celexa) 26

Show all 38 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 36
Sertraline (Zoloft) 27
Venlafaxine (Effexor XR) 19
Citalopram (Celexa) 16
Escitalopram (Lexapro) 15

Show all 38 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

1,492 members have decided to share their profiles only with other members of PatientsLikeMe.

jdlawrence
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jdlawrence
Gender: M
Data Quality: 1 star
Depression: 2
Mania: 1
Emotional: 1
Anxiety: 1
Compulsion: 1
External Stress: Moderate
28 M
Function: Moderate
Distress: Low
I am: vg
I have:
Major Depressive Disorder

See jdlawrence's full Bupropion history

Jun 28, 2016 (Started Aug 15, 2009)

  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: I took this exclusively for two years and found minimal effects. I'm now on Celexa, as well, and the combination is working, but I suspect it's really all the Celexa.

  • 0 helpful marks
LittleBean
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LittleBean
Gender: F
Data Quality: 1 star
Depression: 0
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Low
32 F
Function: High
Distress: Low
I am: n
I have:
ADD (Attention Deficit Disorder)

See LittleBean's full Bupropion history

May 26, 2016 (Started Dec 22, 2013)

  • Effectiveness
    Slight (for Problems concentrating)
  • Effectiveness
    Moderate (for Lack of motivation)
  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Moderate (for ADD (Attention Deficit Disorder))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 450 mg Daily
Advice & Tips: More energy, less irritability.

  • 0 helpful marks
CupcakeKitten
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CupcakeKitten
Gender: F
Data Quality: 3 stars
Depression: 2
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 1
External Stress: Moderate
25 F
Function: Moderate
Distress: Low
I am: g
I have:
Borderline Personality

See CupcakeKitten's full Bupropion history

Apr 18, 2016 (Started Mar 29, 2016)

  • Effectiveness
    Moderate (for Slowness)
  • Effectiveness
    Slight (for Problems concentrating)
  • Effectiveness
    Moderate (for Overwhelming fatigue)
  • Effectiveness
    None (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Fatigue)
  • Effectiveness
    Moderate (for Excessive sleeping (hypersomnia))
  • Effectiveness
    None (for Depressed mood)
  • Effectiveness
    Moderate (for Apathy)
  • Side effects
    Severe (Memory problems, Emotional sensitivity, Sensory sensitivity, Crying for no reason, Anxious mood, Panic attacks, Anger, Irritability, Heart palpitations)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg/24 hours Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion