What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Wellbutrin SR Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,535 845
Depressed mood 1,467 683
Persistent depressive disorder (dysthymia) 299 248
Mild Depression 131 49
Anxious mood 113 51
Bipolar Disorder 95 80

Show all 201 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 207
Moderate 282
Mild 473
None 813

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 83
Anxious mood 49
Insomnia 44
Constipation 36
Headaches 36
Weight gain 35

Show all 369 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 80
300 mg daily 70
300 mg/24 hours daily 69
100 mg daily 42
150 mg/24 hours daily 35
75 mg daily 24
450 mg daily 24
100 mg twice daily 20
150 mg twice daily 17
200 mg daily 14

See all 53 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 504
Side effects too severe 425
Doctor's advice 344
Other 239
Course of treatment ended 75
Expense 75
Personal research 62
Change in health plan coverage 34
See all 1272 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 2
1 - 6 months 32
6 months - 1 year 45
1 - 2 years 76
2 - 5 years 128
5 - 10 years 129
10 years or more 75

Stopped taking Bupropion

Duration Patients
Less than 1 month 241
1 - 6 months 313
6 months - 1 year 197
1 - 2 years 184
2 - 5 years 229
5 - 10 years 103
10 years or more 43
Adherence
Adherence Evaluations
Always 1395
Usually 283
Sometimes 41
Never taken as prescribed 56
Burden
Burden Evaluations
Very hard to take 58
Somewhat hard to take 103
A little hard to take 270
Not at all hard to take 1344
Cost per month
Cost per month Evaluations
$200+ 11
$100-199 21
$50-99 71
$25-49 147
< $25 863
Not specified 662

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 44
Venlafaxine (Effexor XR) 35
Fluoxetine (Prozac) 32
Duloxetine (Cymbalta) 27
Citalopram (Celexa) 19

Show all 35 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 26
Sertraline (Zoloft) 23
Venlafaxine (Effexor XR) 17
Bupropion (Wellbutrin XL) 13
Citalopram (Celexa) 12

Show all 33 treatments patients report switching to

Last updated:

183 patient evaluations for Bupropion

1,326 members have decided to share their profiles only with other members of PatientsLikeMe.

stargeek
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stargeek
Gender: M
Data Quality: 1 star
Depression: 3
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 2
External Stress: Severe
47 M
Function: Moderate
Distress: Moderate
I am: b
I have:
Major Depressive Disorder

See stargeek's full Bupropion history

Dec 24, 2015 (Started Apr 11, 2013)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Cost: < $25 monthly

  • 0 helpful marks
zoomer
60535 thumb
zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Low
61 F
Function: High
Distress: Low
I am: vg
I have:
Bipolar I

See zoomer's full Bupropion history

Nov 29, 2015 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Just wanting to update. I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines.
Cost: < $25 monthly

Apr 6, 2011 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking wellbutrin. I don't allocate all credit to this med. I take Pristiq also. So, did it help me quit smoking? not yet.
Cost: < $25 monthly

Oct 25, 2010 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have noticed a more consistent level of lower anxiety on Wellbutrin. It has also noticeably helped decrease the depression a degree during episodes. I have also decreased my tabacco intake since taking .
Cost: < $25 monthly

  • 1 helpful mark
John Jamson
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John Jamson
Gender: M
Data Quality: 1 star
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 1
External Stress: Severe
35 M
Function: High
Distress: Low
I am: n
I have:
Major Depressive Disorder

See John Jamson's full Bupropion history

Nov 13, 2015 (Started Sep 18, 2009)

  • Effectiveness
    Moderate (for Persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    None (for Fatigue)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Cost: $25-49 monthly

Oct 4, 2014 (Started Sep 18, 2009)

  • Effectiveness
    Moderate (for Fatigue)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 183 patient evaluations for Bupropion