What is Bupropion?

Category: Prescription Drugs

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,844 1,063
Depressed mood 1,518 720
Persistent depressive disorder (dysthymia) 341 285
Mild Depression 139 56
Anxious mood 114 55
Bipolar Disorder 102 85

Show all 207 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 234
Moderate 333
Mild 548
None 953

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 93
Anxious mood 56
Weight gain 49
Insomnia 46
Headaches 42
Constipation 41

Show all 416 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 135
150 mg daily 128
100 mg daily 79
300 mg/24 hours daily 72
75 mg daily 49
450 mg daily 49
100 mg twice daily 41
150 mg/24 hours daily 27
150 mg twice daily 26
200 mg daily 24

See all 71 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 563
Side effects too severe 481
Doctor's advice 372
Other 250
Course of treatment ended 81
Expense 78
Personal research 67
Change in health plan coverage 36
See all 1390 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 8
1 - 6 months 59
6 months - 1 year 81
1 - 2 years 130
2 - 5 years 178
5 - 10 years 182
10 years or more 130

Stopped taking Bupropion

Duration Patients
Less than 1 month 278
1 - 6 months 330
6 months - 1 year 220
1 - 2 years 204
2 - 5 years 242
5 - 10 years 110
10 years or more 47
Adherence
Adherence Evaluations
Always 1613
Usually 321
Sometimes 45
Never taken as prescribed 89
Burden
Burden Evaluations
Very hard to take 69
Somewhat hard to take 127
A little hard to take 314
Not at all hard to take 1558
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 25
$50-99 78
$25-49 158
< $25 1007
Not specified 790

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 66
Fluoxetine (Prozac) 56
Venlafaxine (Effexor XR) 53
Duloxetine (Cymbalta) 38
Citalopram (Celexa) 31

Show all 39 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 39
Sertraline (Zoloft) 31
Venlafaxine (Effexor XR) 24
Fluoxetine (Prozac) 20
Citalopram (Celexa) 19

Show all 40 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,581 members have decided to share their profiles only with other members of PatientsLikeMe.

leejon66
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leejon66
Gender: M
Data Quality: 3 stars
Depression: 0
Mania: 0
Emotional: 1
Anxiety: 2
Compulsion: 0
External Stress: Low
68 M
Function: High
Distress: Low
I am: n
I have:
PTSD

See leejon66's full Bupropion history

Aug 5, 2016 (Started Jul 01, 1979)

  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg One time

Jun 5, 2015 (Started Jul 01, 1979)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: you need to talk to your Doctor about this treatment plan. some say it is to expense. I get my medIdecation from the VA

  • 0 helpful marks
jdlawrence
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jdlawrence
Gender: M
Data Quality: 1 star
Depression: 2
Mania: 1
Emotional: 1
Anxiety: 1
Compulsion: 1
External Stress: Moderate
28 M
Function: Moderate
Distress: Low
I am: vg
I have:
Major Depressive Disorder

See jdlawrence's full Bupropion history

Jun 28, 2016 (Started Aug 15, 2009)

  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: I took this exclusively for two years and found minimal effects. I'm now on Celexa, as well, and the combination is working, but I suspect it's really all the Celexa.

  • 0 helpful marks
LittleBean
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LittleBean
Gender: F
Data Quality: 1 star
Depression: 0
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Low
32 F
Function: High
Distress: Low
I am: b
I have:
ADD (Attention Deficit Disorder)

See LittleBean's full Bupropion history

May 26, 2016 (Started Dec 22, 2013)

  • Effectiveness
    Slight (for Problems concentrating)
  • Effectiveness
    Moderate (for Lack of motivation)
  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Moderate (for ADD (Attention Deficit Disorder))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 450 mg Daily
Advice & Tips: More energy, less irritability.

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion