What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,996 1,153
Depressed mood 1,541 739
Persistent depressive disorder (dysthymia) 357 295
Mild Depression 143 59
Anxious mood 116 58
Bipolar Disorder 105 90

Show all 209 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 244
Moderate 354
Mild 573
None 1,019

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 101
Anxious mood 59
Weight gain 53
Insomnia 49
Headaches 48
Constipation 41

Show all 426 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 154
300 mg daily 150
100 mg daily 99
300 mg/24 hours daily 71
75 mg daily 60
450 mg daily 45
100 mg twice daily 44
150 mg twice daily 37
150 mg/24 hours daily 27
200 mg daily 27

See all 83 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 597
Side effects too severe 500
Doctor's advice 384
Other 259
Course of treatment ended 84
Expense 81
Personal research 69
Change in health plan coverage 39
See all 1459 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 7
1 - 6 months 87
6 months - 1 year 103
1 - 2 years 150
2 - 5 years 193
5 - 10 years 195
10 years or more 155

Stopped taking Bupropion

Duration Patients
Less than 1 month 297
1 - 6 months 343
6 months - 1 year 236
1 - 2 years 209
2 - 5 years 252
5 - 10 years 111
10 years or more 51
Adherence
Adherence Evaluations
Always 1709
Usually 335
Sometimes 47
Never taken as prescribed 99
Burden
Burden Evaluations
Very hard to take 74
Somewhat hard to take 138
A little hard to take 327
Not at all hard to take 1651
Cost per month
Cost per month Evaluations
$200+ 12
$100-199 25
$50-99 82
$25-49 163
< $25 1060
Not specified 848

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 77
Fluoxetine (Prozac) 69
Venlafaxine (Effexor XR) 59
Citalopram (Celexa) 41
Duloxetine (Cymbalta) 39

Show all 50 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 43
Sertraline (Zoloft) 38
Venlafaxine (Effexor XR) 28
Fluoxetine (Prozac) 23
Citalopram (Celexa) 22

Show all 41 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,686 members have decided to share their profiles only with other members of PatientsLikeMe.

COOPERATI
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COOPERATI
Gender: M
Data Quality: 2 stars
Depression: 3
Mania: 2
Emotional: 4
Anxiety: 2
Compulsion: 2
External Stress: Overwhelming
43 M
Function: Low
Distress: High
I am: vb
I have:
Schizophrenia

See COOPERATI's full Bupropion history

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks
COOPERATI
22007 thumb
COOPERATI
Gender: M
Data Quality: 2 stars
Depression: 3
Mania: 2
Emotional: 4
Anxiety: 2
Compulsion: 2
External Stress: Overwhelming
43 M
Function: Low
Distress: High
I am: vb
I have:
Schizophrenia

See COOPERATI's full Bupropion history

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks
AnnieOakley
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AnnieOakley
Gender: F
Data Quality: 3 stars
Pain: Some
Fatigue: Most
Sleep: Most
Stiffness: All
function: None
external_stress: Most
Stickman: most
Description:F44y
FM:8y Dx
I am: n
I have:
Fibromyalgia

See AnnieOakley's full Bupropion history

Apr 15, 2017 (Started Jan 15, 2014)

  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I was told I would probably lose weight on this, but I didn't.
Cost: $25-49 monthly

Sep 15, 2014 (Started Jan 15, 2014)

  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion