What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,328 1,319
Depressed mood 1,622 809
Persistent depressive disorder (dysthymia) 407 334
Mild depression 155 69
Anxious mood 121 66

Show all 188 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 279
Moderate 382
Mild 625
None 1,155

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 108
Anxious mood 70
Weight gain 58
Insomnia 54
Headaches 48
Constipation 43

Show all 370 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 166
150 mg daily 126
100 mg daily 68
300 mg/24 hours daily 59
450 mg daily 50
75 mg daily 42
150 mg twice daily 38
100 mg twice daily 27
150 mg/24 hours daily 21
200 mg daily 21

See all 59 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 664
Side effects too severe 562
Doctor's advice 436
Other 279
Course of treatment ended 95
Expense 84
Personal research 73
Change in health plan coverage 44
See all 1628 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 2
1 - 6 months 37
6 months - 1 year 40
1 - 2 years 104
2 - 5 years 198
5 - 10 years 193
10 years or more 165

Stopped taking Bupropion

Duration Patients
Less than 1 month 361
1 - 6 months 358
6 months - 1 year 236
1 - 2 years 233
2 - 5 years 287
5 - 10 years 127
10 years or more 64
Adherence
Adherence Evaluations
Always 1914
Usually 361
Sometimes 51
Never taken as prescribed 115
Burden
Burden Evaluations
Very hard to take 84
Somewhat hard to take 146
A little hard to take 345
Not at all hard to take 1866
Cost per month
Cost per month Evaluations
$200+ 16
$100-199 27
$50-99 86
$25-49 177
< $25 1170
Not specified 965

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 95
Fluoxetine (Prozac) 92
Venlafaxine (Effexor XR) 75
Citalopram (Celexa) 54
Duloxetine (Cymbalta) 49

Show all 55 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 33
Escitalopram (Lexapro) 31

Show all 48 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Jul 8, 2018 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 175 mg Daily
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Dec 18, 2013 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Oct 20, 2010 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Aug 30, 2010 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Jul 16, 2009 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

  • 0 helpful marks

Apr 11, 2018 (Started May 15, 2017)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Cost: $200+ monthly

  • 0 helpful marks

Jan 12, 2018 (Started Jun 30, 2017)

  • Effectiveness
    Moderate (for chronic fatigue)
  • Side effects
    Severe (vomiting, nausea)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion