What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,262 1,277
Depressed mood 1,608 786
Persistent depressive disorder (dysthymia) 394 322
Mild depression 153 65
Anxious mood 121 64

Show all 195 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
269
Moderate
374
Mild
613
None
1,114

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 106
Anxious mood 69
Weight gain 54
Insomnia 50
Headaches 48
Constipation 43

Show all 447 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 182
150 mg daily 142
100 mg daily 78
300 mg/24 hours daily 63
450 mg daily 57
75 mg daily 56
150 mg twice daily 34
200 mg daily 32
100 mg twice daily 31
150 mg/24 hours daily 25

See all 77 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 650
Side effects too severe 550
Doctor's advice 421
Other 274
Course of treatment ended 89
Expense 81
Personal research 70
Change in health plan coverage 43
See all 1583 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 1
1 - 6 months 52
6 months - 1 year 98
1 - 2 years 113
2 - 5 years 222
5 - 10 years 191
10 years or more 176

Stopped taking Bupropion

Duration Patients
Less than 1 month 350
1 - 6 months 352
6 months - 1 year 233
1 - 2 years 228
2 - 5 years 275
5 - 10 years 122
10 years or more 60
Adherence
Adherence Evaluations
Always 1853
Usually 353
Sometimes 54
Never taken as prescribed 110
Burden
Burden Evaluations
Very hard to take 82
Somewhat hard to take 146
A little hard to take 338
Not at all hard to take 1804
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 85
$25-49 174
< $25 1146
Not specified 927

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 93
Fluoxetine (Prozac) 87
Venlafaxine (Effexor XR) 72
Citalopram (Celexa) 51
Duloxetine (Cymbalta) 48

Show all 57 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Sertraline (Zoloft) 48
Duloxetine (Cymbalta) 46
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 31
Escitalopram (Lexapro) 29

Show all 46 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

Jan 12, 2018 (Started Jun 30, 2017)

  • Effectiveness
    Moderate (for chronic fatigue)
  • Side effects
    Severe (vomiting, nausea)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Dec 15, 2017 (Started Jun 01, 2006)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Severe (insomnia, hot flashes, feeling tense or on edge, feeling feverish, facial flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: If you are taking the generic extended release make sure it is not dose dumping - releasing too much medicine at once causing side effects. My MS doctor, PCP, and I thought I was in menopause with all the hot flashes and fevers of 99.6! Even kept going in to see if I had a UTI bc of the fevers! What a waste of my time and money!!!
Cost: < $25 monthly

  • 0 helpful marks

Dec 1, 2017 (Started Jul 01, 2007)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Cost: $50-99 monthly

Apr 8, 2012 (Started Jul 01, 2007)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (morning nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: I use a pill organizer to keep track of whether or not I have taken my pills for the day and take them at the same time every day. I take pills at night when possible to minimize nausea.
Cost: $100-199 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion