What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,301 1,297
Depressed mood 1,616 800
Persistent depressive disorder (dysthymia) 402 328
Mild depression 155 68
Anxious mood 121 66
Bipolar disorder 112 94

Show all 194 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 272
Moderate 380
Mild 616
None 1,140

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 107
Anxious mood 71
Weight gain 58
Insomnia 52
Headaches 48
Constipation 43

Show all 441 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 188
150 mg daily 147
100 mg daily 67
300 mg/24 hours daily 66
450 mg daily 53
75 mg daily 48
150 mg twice daily 41
100 mg twice daily 29
200 mg daily 29
150 mg/24 hours daily 26

See all 66 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 659
Side effects too severe 557
Doctor's advice 427
Other 281
Course of treatment ended 92
Expense 85
Personal research 73
Change in health plan coverage 44
See all 1613 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 4
1 - 6 months 38
6 months - 1 year 96
1 - 2 years 116
2 - 5 years 226
5 - 10 years 196
10 years or more 167

Stopped taking Bupropion

Duration Patients
Less than 1 month 357
1 - 6 months 356
6 months - 1 year 235
1 - 2 years 231
2 - 5 years 283
5 - 10 years 127
10 years or more 64
Adherence
Adherence Evaluations
Always 1887
Usually 356
Sometimes 52
Never taken as prescribed 113
Burden
Burden Evaluations
Very hard to take 82
Somewhat hard to take 147
A little hard to take 341
Not at all hard to take 1838
Cost per month
Cost per month Evaluations
$200+ 15
$100-199 26
$50-99 86
$25-49 174
< $25 1160
Not specified 947

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 96
Fluoxetine (Prozac) 91
Venlafaxine (Effexor XR) 73
Citalopram (Celexa) 51
Duloxetine (Cymbalta) 48

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 32
Fluoxetine (Prozac) 31

Show all 48 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Apr 11, 2018 (Started May 15, 2017)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Cost: $200+ monthly

  • 0 helpful marks

Jan 12, 2018 (Started Jun 30, 2017)

  • Effectiveness
    Moderate (for chronic fatigue)
  • Side effects
    Severe (vomiting, nausea)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Dec 15, 2017 (Started Jun 01, 2006)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Severe (insomnia, hot flashes, feeling tense or on edge, feeling feverish, facial flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: If you are taking the generic extended release make sure it is not dose dumping - releasing too much medicine at once causing side effects. My MS doctor, PCP, and I thought I was in menopause with all the hot flashes and fevers of 99.6! Even kept going in to see if I had a UTI bc of the fevers! What a waste of my time and money!!!
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion