What is Mesalamine?

Category: Prescription Drugs

Most popular types: Pentasa Asacol Lialda Show all

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Mesalamine, a derivative of 5-aminosalicylic acid, is an anti-inflammatory agent. It can be used to treat ulcerative colitis and Crohn’s disease. It can be taken orally or applied rectally to help treat the inflammation associated with these conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Crohn's disease 262 108
Ulcerative colitis 199 109
Microscopic colitis 7 6
Diarrhea 5 5
Chronic diarrhea 3 2

Show all 22 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 12
Moderate 29
Mild 34
None 156

Commonly reported side effects and conditions associated with Mesalamine

Side effect Patients Percentage
Headaches 10
Diarrhea 7
Nausea 6
Hair loss 5
Fatigue 4
Abdominal pain 3

Show all 71 reported side effects

Dosages

Based on patients currently taking Mesalamine

Dosage Patients Percentage
4800 mg daily 4
2.4 g daily 3
4.8 g daily 2
1000 mg four times daily 2
4 x 1,200 mg daily 2
0.75 g daily 1
1.2 g daily 1
1.2 g twice daily 1
3 g daily 1
4 capsule(s) daily 1

See all 33 dosages

Why patients stopped taking Mesalamine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 101
Doctor's advice 62
Side effects too severe 38
Other 28
Course of treatment ended 18
Expense 17
Change in health plan coverage 9
Personal research 9
See all 186 patients who've stopped taking Mesalamine

Duration

Currently taking Mesalamine

Duration Patients Percentage
1 - 6 months 1
6 months - 1 year 1
1 - 2 years 5
2 - 5 years 12
5 - 10 years 16
10 years or more 8

Stopped taking Mesalamine

Duration Patients Percentage
Less than 1 month 48
1 - 6 months 42
6 months - 1 year 21
1 - 2 years 25
2 - 5 years 21
5 - 10 years 20
10 years or more 19
Adherence
Adherence Evaluations Percentage
Always 174
Usually 40
Sometimes 7
Never taken as prescribed 10
Burden
Burden Evaluations Percentage
Very hard to take 15
Somewhat hard to take 34
A little hard to take 52
Not at all hard to take 130
Cost per month
Cost per month Evaluations Percentage
$200+ 17
$100-199 9
$50-99 11
$25-49 26
< $25 61
Not specified 107

What people switch to and from

Patients started taking Mesalamine after stopping:

Treatment Patients Percentage
Sulfasalazine (Salazopyrin) 14
Mesalamine (Pentasa) 6
Balsalazide (Colazal) 4
Azathioprine (Imuran) 2
Infliximab (Remicade) 2

Show all 9 treatments patients report switching from

Patients stopped taking Mesalamine and switched to:

Treatment Patients Percentage
Sulfasalazine (Salazopyrin) 8
Infliximab (Remicade) 7
Mesalamine (Pentasa) 6
Adalimumab (Humira) 4
Azathioprine (Imuran) 4

Show all 16 treatments patients report switching to

Last updated:

11 patient evaluations for Mesalamine

Jul 11, 2015 (Started Jan 15, 2014)

  • Effectiveness
    Moderate (for Crohn's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2.4 g Daily
Cost: $50-99 monthly

  • 0 helpful marks

May 31, 2014 (Started Oct 05, 2011)

  • Effectiveness
    Major (for gastrointestinal bleeding)
  • Effectiveness
    Major (for Crohn's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 3200 mg Daily
Advice & Tips: For some reason the Oregon Health Plan (new Obama-care insurance) does not cover Asacol HD 800mg TBEC. My recent flare-up may have been exacerbated because I ran out of the medication and couldn't get it refilled. For the last 2 weeks I have been paying out-of-pocket for it and it is EXPENSIVE. I will have to either find another medication option on Monday or work on the appeal process (which looks like a pain in the ass). Until then I will be paying out the whazoo for it because it is the only medication I know of that really can keep me in remission without noticeable side effects.
Cost: $200+ monthly

  • 0 helpful marks

Nov 24, 2012 (Started May 10, 2012)

  • Effectiveness
    Can't tell (for ulcerative colitis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 11 patient evaluations for Mesalamine