What is Temozolomide?

Category: Prescription Drugs

Most popular types: Temodar

false

Temozolomide is an anti-cancer agent used to treat newly-diagnosed glioblastoma multiforme (initially in combination with radiotherapy, then as maintenance treatment); and for refractory anaplastic astrocytoma.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Glioblastoma 10 9
Astrocytoma 9 28
Melanoma 4 1
Neuroendocrine tumor 2 3
Oligodendroglioma 1 0
Pancreatic neuroendocrine tumor 1 1

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 3
Moderate 1
Mild 32
None 3

Commonly reported side effects and conditions associated with Temozolomide

Side effect Patients Percentage
Fatigue 8
Nausea 5
Brain fog 1
Sleepiness 1
Tiredness 1

Why patients stopped taking Temozolomide

Multiple reasons could be selected

Reason Patients Percentage
Course of treatment ended 7
Other 5
Doctor's advice 4
Did not seem to work 1
Side effects too severe 1
See all 15 patients who've stopped taking Temozolomide

Duration

Stopped taking Temozolomide

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 3
6 months - 1 year 7
1 - 2 years 3
5 - 10 years 1
Adherence
Adherence Evaluations Percentage
Always 38
Usually 0
Sometimes 0
Never taken as prescribed 1
Burden
Burden Evaluations Percentage
Very hard to take 2
Somewhat hard to take 1
A little hard to take 18
Not at all hard to take 18
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 1
$50-99 4
$25-49 2
< $25 24
Not specified 8

What people switch to and from

Patients started taking Temozolomide after stopping:

Treatment Patients Percentage
Everolimus (Afinitor) 1

Patients stopped taking Temozolomide and switched to:

Treatment Patients Percentage
Bevacizumab (Avastin) 1
Octreotide (Sandostatin) 1
Last updated:

3 patient evaluations for Temozolomide

Mar 11, 2015 (Started Dec 29, 2014)

  • Effectiveness
    Can't tell (for glioblastoma)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Advice & Tips: at double the dose on this cycle, just beginning to get used to the fatigue. no nausea yet. I take the chemo in the middle of the night when I can to, which means not worry about meal an beverage timing

Mar 1, 2015 (Started Dec 29, 2014)

  • Effectiveness
    Can't tell (for glioblastoma)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I am, it appears, very, VERY lucky. I've since met people who can recount dreadful stories of their (or their partners) journey with Temozolomide, but I had more difficulty with multivitamins... Really! at the chemo/radio dose, its been a breeze. i will report again when i start the new 'double dose' for the 6 cycle chemon only period, but I am told some get it easy, some don't - I hope you get it easy too.

  • 0 helpful marks

Mar 19, 2013 (Started Oct 15, 2012)

  • Effectiveness
    Slight (for glioblastoma)
  • Side effects
    Mild (side effects when dose skipped, fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 140 mg Daily
Advice & Tips: First time on Temodar in 2008 I was concurrently receiving radiation treatment. At that time I was tied to a toilet. This time around I think it only makes me tired and the mucus thing when I resume after a break.

  • 0 helpful marks

Dec 7, 2009 (Started Jan 19, 2009)

  • Effectiveness
    Moderate (for Other)
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 140 mg Daily
Cost: $50-99 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Temozolomide