What is Tacrolimus?

Category: Prescription Drugs

Most popular types: Prograf Advagraf Envarsus XR

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Tacrolimus (FK506) is an immunosuppressant agent. Taken orally or by injection it is used to prevent organ rejection in heart, kidney, or liver transplant recipients. Used as a topical skin product it is used for moderate-to-severe atopic dermatitis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent organ rejection 595 121
Kidney transplant 59 28
Lung transplant 15 4
Liver transplant 9 6
Heart transplant 8 3

Show all 22 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 18
Moderate 51
Mild 73
None 49

Commonly reported side effects and conditions associated with Tacrolimus

Side effect Patients Percentage
Tremor in hands 26
Hair loss 21
Fatigue 11
Hair thinning 9
Shakiness 9
Shaky hands 9

Show all 103 reported side effects

Dosages

Based on patients currently taking Tacrolimus

Dosage Patients Percentage
1 mg twice daily 4
5 mg daily 2
3 mg twice daily 2
7 mg daily 2
1 mg daily 1
2.5 tablet(s) daily 1
1.5 mg twice daily 1
1.5 tablet(s) twice daily 1
3 capsule(s) daily 1
3 mg daily 1

See all 13 dosages

Why patients stopped taking Tacrolimus

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 21
Doctor's advice 14
Other 9
Course of treatment ended 7
Did not seem to work 6
Change in health plan coverage 2
Expense 2
Personal research 1
See all 47 patients who've stopped taking Tacrolimus

Duration

Currently taking Tacrolimus

Duration Patients Percentage
1 - 6 months 1
6 months - 1 year 1
1 - 2 years 1
2 - 5 years 2
5 - 10 years 8
10 years or more 8

Stopped taking Tacrolimus

Duration Patients Percentage
Less than 1 month 5
1 - 6 months 11
6 months - 1 year 7
1 - 2 years 6
2 - 5 years 11
5 - 10 years 6
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 177
Usually 10
Sometimes 2
Never taken as prescribed 2
Burden
Burden Evaluations Percentage
Very hard to take 5
Somewhat hard to take 7
A little hard to take 24
Not at all hard to take 155
Cost per month
Cost per month Evaluations Percentage
$200+ 8
$100-199 9
$50-99 9
$25-49 8
< $25 78
Not specified 79

What people switch to and from

Patients started taking Tacrolimus after stopping:

Treatment Patients Percentage
Mycophenolate mofetil (CellCept) 3
Azathioprine (Imuran) 2
Betamethasone-calcipotriene topical (Dovobet) 1
Cyclosporine (Neoral) 1
Sirolimus (Rapamune) 1

Patients stopped taking Tacrolimus and switched to:

Treatment Patients Percentage
Mycophenolate mofetil (CellCept) 2
Sirolimus (Rapamune) 2
Last updated:

27 patient evaluations for Tacrolimus

Jul 9, 2015 (Started Sep 01, 2010)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 mg Twice daily

  • 0 helpful marks

Feb 6, 2012 (Started Dec 01, 2009)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Moderate (flu virus (influenza))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg Daily
Cost: $100-199 monthly

  • 0 helpful marks

Nov 1, 2011 (Started Dec 16, 2010)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Moderate (tremor in hands, hair loss, hair thinning)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3.5 mg/kg/day Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 27 patient evaluations for Tacrolimus