What is Sulfasalazine?

Category: Prescription Drugs

Most popular types: Salazopyrin Sulfazine Azulfidine Show all

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Sulfasalazine is a 5-aminosalicylic acid derivative used primarily for ulcerative colitis and rheumatoid arthritis. It has many other uses including ankylosing spondylitis, collagenous colitis, Crohn's disease, psoriasis, psoriatic arthritis, juvenile chronic arthritis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid arthritis 385 160
Crohn's disease 74 22
Psoriatic arthritis 55 16
Ulcerative colitis 55 24
Ankylosing spondylitis 31 12

Show all 32 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 58
Moderate 47
Mild 54
None 105

Commonly reported side effects and conditions associated with Sulfasalazine

Side effect Patients Percentage
Nausea 29
Headaches 18
Rashes (redness, swelling) 8
Diarrhea 7
Fatigue 6
Stomach pain 6

Show all 103 reported side effects

Dosages

Based on patients currently taking Sulfasalazine

Dosage Patients Percentage
1500 mg twice daily 7
500 mg twice daily 6
1000 mg twice daily 6
2000 mg daily 4
500 mg daily 3
3000 mg daily 2
1000 mg three times daily 1
2000 mg twice daily 1
1000 mg five times daily 1

Why patients stopped taking Sulfasalazine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 142
Side effects too severe 133
Doctor's advice 88
Other 40
Course of treatment ended 18
Personal research 10
Expense 5
Change in health plan coverage 4
See all 316 patients who've stopped taking Sulfasalazine

Duration

Currently taking Sulfasalazine

Duration Patients Percentage
1 - 6 months 1
6 months - 1 year 1
1 - 2 years 6
2 - 5 years 10
5 - 10 years 7
10 years or more 8

Stopped taking Sulfasalazine

Duration Patients Percentage
Less than 1 month 76
1 - 6 months 77
6 months - 1 year 44
1 - 2 years 37
2 - 5 years 52
5 - 10 years 15
10 years or more 16
Adherence
Adherence Evaluations Percentage
Always 208
Usually 34
Sometimes 7
Never taken as prescribed 15
Burden
Burden Evaluations Percentage
Very hard to take 22
Somewhat hard to take 23
A little hard to take 50
Not at all hard to take 169
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 2
$50-99 2
$25-49 15
< $25 104
Not specified 140

What people switch to and from

Patients started taking Sulfasalazine after stopping:

Treatment Patients Percentage
Methotrexate (Trexall) 19
Hydroxychloroquine (Plaquenil) 9
Mesalamine (Pentasa) 9
Adalimumab (Humira) 7
Leflunomide (Arava) 7

Show all 19 treatments patients report switching from

Patients stopped taking Sulfasalazine and switched to:

Treatment Patients Percentage
Methotrexate (Trexall) 11
Mesalamine (Pentasa) 9
Hydroxychloroquine (Plaquenil) 6
Infliximab (Remicade) 6
Leflunomide (Arava) 6

Show all 21 treatments patients report switching to

Last updated:

18 patient evaluations for Sulfasalazine

Apr 5, 2017 (Started Feb 09, 2009)

  • Effectiveness
    Can't tell (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 3000 mg Daily
Cost: < $25 monthly

Jun 7, 2013 (Started Feb 09, 2009)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: Sulfasalazine seems to build up in my body, so it does not help if I only took the med before bedtime. Even the side effect is rather mild, it is present 24/7 and I can't have it.

Mar 18, 2013 (Started Feb 09, 2009)

  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily

Dec 3, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: Det var en ubetinget succes at gå ned til 500mg. Det kunne kun lade sig gøre fordi jeg satte mtx dosis op til 9 pr uge. En dag tager jeg mod til mig og dropper Sulfasalazine fuldstændigt som forsøg.

Oct 5, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily
Advice & Tips: I 7 uger har jeg kun taget 2 stk (1000mg) og det har reduceret kvalmen ganske betydeligt. På mandag sætter jeg det ned til 1 stk (500mg)

Jul 6, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 1500 mg Daily
Advice & Tips: Take quarter dose in the morning, quarter in the evening and half before bedtime

  • 0 helpful marks

Jan 15, 2016 (Started Jan 15, 2015)

  • Effectiveness
    Can't tell (for ankylosing spondylitis)
  • Side effects
    Moderate (diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1500 mg Twice daily

  • 0 helpful marks

Jul 1, 2014 (Started Feb 15, 2012)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: RA went into remission.

Jul 1, 2013 (Started Feb 15, 2012)

  • Effectiveness
    Major (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 18 patient evaluations for Sulfasalazine