What is Sulfamethoxazole-Trimethoprim (cotrimoxazole)?

Category: Prescription Drugs

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Sulfamethoxazole-trimethoprim, also known as SMX-TMP or cotrimoxazole, is a combination of sulfamethoxazole, an antibacterial sulfonamide, and trimethoprim. The combination eliminates bacteria that cause many kinds of infections, including pneumonia and urinary tract and intestinal infections.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent infection 188 89
Urinary tract infection 67 40
Sinus infection (sinusitis) 25 11
Human immunodeficiency virus (HIV) 16 4
General health 15 6

Show all 68 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 19
Moderate 18
Mild 44
None 143

Commonly reported side effects and conditions associated with Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Side effect Patients Percentage
Nausea 7
Diarrhea 5
Abdominal cramps 2
Anxious mood 2
Sensitivity to medications 2
Skin sensitivity to sun (photosensitivity) 2

Show all 62 reported side effects

Dosages

Based on patients currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Dosage Patients Percentage
800-160 mg twice daily 4
800-160 mg m,w,f 3
400-80 mg daily 3
800-160 mg daily 3
1 tablet(s) m,w,f 1
100 mg daily 1
400 mg-80 mg daily 1
200-40 mg/5ml three times daily 1
2 x 400 mg-80 mg daily 1
400 mg-80 mg twice daily 1

See all 15 dosages

Why patients stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Multiple reasons could be selected

Reason Patients Percentage
Course of treatment ended 154
Doctor's advice 63
Side effects too severe 30
Did not seem to work 16
Other 14
Personal research 2
See all 241 patients who've stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration

Currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 1
6 months - 1 year 1
1 - 2 years 4
2 - 5 years 12
5 - 10 years 4
10 years or more 2

Stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration Patients Percentage
Less than 1 month 116
1 - 6 months 56
6 months - 1 year 32
1 - 2 years 23
2 - 5 years 13
5 - 10 years 5
10 years or more 3
Adherence
Adherence Evaluations Percentage
Always 186
Usually 21
Sometimes 7
Never taken as prescribed 10
Burden
Burden Evaluations Percentage
Very hard to take 8
Somewhat hard to take 9
A little hard to take 32
Not at all hard to take 175
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 1
$25-49 9
< $25 121
Not specified 93

What people switch to and from

Patients started taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) after stopping:

Treatment Patients Percentage
Cephalexin (Keflex) 3
Ciprofloxacin (Cipro) 2
Clarithromycin (Biaxin) 2
Amoxicillin-clavulanate (Augmentin) 1
Azithromycin (Zithromax) 1

Show all 13 treatments patients report switching from

Patients stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) and switched to:

Treatment Patients Percentage
Dapsone (DDS) (Aczone) 2
Levofloxacin (Levaquin) 2
Amoxicillin (Amoxil) 1
Artemether-lumefantrine 1
Atovaquone (Mepron) 1

Show all 15 treatments patients report switching to

Last updated:

25 patient evaluations for Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Aug 23, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for cysts)
  • Side effects
    Mild (nausea, upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Advice & Tips: Cyst is almost gone
Cost: < $25 monthly

Aug 19, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for cysts)
  • Side effects
    Mild (nausea, upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Advice & Tips: My stomach feels upset from time to time on days when I take this. The cyst I'm taking this for has shrunk, could be gone in a week.
Cost: < $25 monthly

Aug 15, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for cysts)
  • Side effects
    Mild (nausea, upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Jan 6, 2014 (Started Dec 13, 2013)

  • Effectiveness
    Moderate (for urinary tract infection)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Cost: < $25 monthly

Dec 26, 2013 (Started Dec 13, 2013)

  • Effectiveness
    Moderate (for urinary tract infection)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 2 x 200 mg-40 mg/5 mL Daily
Cost: < $25 monthly

  • 0 helpful marks

Dec 23, 2012 (Started Dec 22, 2012)

  • Effectiveness
    Moderate (for urinary tract infection)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 1200 mg Daily
Advice & Tips: good for clearing Urinary infection
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 25 patient evaluations for Sulfamethoxazole-Trimethoprim (cotrimoxazole)