What is Selegiline?

Category: Prescription Drugs

Most popular types: Zelapar Emsam Eldepryl Show all

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See also: Xilopar

Selegiline is an antidepressant and anti-Parkinson's agent. Orally it is used as an adjunct to levodopa/carbidopa therapy for Parkinson's disease; transdermally it is used for major depressive disorder. It has also been used for ADHD; negative symptoms of schizophrenia and extrapyramidal symptoms.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 360 143
Depressed mood 39 39
Major depressive disorder 17 16
Stiffness/spasticity 12 2
Fatigue 7 1

Show all 36 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 32
Moderate 23
Mild 32
None 111

Commonly reported side effects and conditions associated with Selegiline

Side effect Patients Percentage
Insomnia 7
Nausea 4
Diarrhea 3
Dizziness 3
Drowsiness 3
Headaches 3

Show all 61 reported side effects

Dosages

Based on patients currently taking Selegiline

Dosage Patients Percentage
5 mg twice daily 13
10 mg daily 8
5 mg daily 5
1.25 mg daily 1
2.5 mg daily 1
10 mg twice daily 1
20 mg twice daily 1
daily 1

Why patients stopped taking Selegiline

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 73
Doctor's advice 62
Side effects too severe 47
Other 28
Personal research 12
Expense 9
Course of treatment ended 7
Change in health plan coverage 4
See all 182 patients who've stopped taking Selegiline

Duration

Currently taking Selegiline

Duration Patients Percentage
1 - 2 years 3
2 - 5 years 9
5 - 10 years 15
10 years or more 4

Stopped taking Selegiline

Duration Patients Percentage
Less than 1 month 30
1 - 6 months 40
6 months - 1 year 24
1 - 2 years 36
2 - 5 years 35
5 - 10 years 13
10 years or more 8
Adherence
Adherence Evaluations Percentage
Always 156
Usually 25
Sometimes 2
Never taken as prescribed 15
Burden
Burden Evaluations Percentage
Very hard to take 10
Somewhat hard to take 14
A little hard to take 29
Not at all hard to take 145
Cost per month
Cost per month Evaluations Percentage
$200+ 5
$100-199 2
$50-99 22
$25-49 27
< $25 66
Not specified 76

What people switch to and from

Patients started taking Selegiline after stopping:

Treatment Patients Percentage
Rasagiline (Azilect) 9
Duloxetine (Cymbalta) 3
Bupropion (Wellbutrin XL) 2
Carbidopa-Levodopa (Sinemet) 2
Entacapone (Comtan) 2

Show all 18 treatments patients report switching from

Patients stopped taking Selegiline and switched to:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 4
Rasagiline (Azilect) 2
Tranylcypromine (Parnate) 2
Amantadine (Symmetrel) 1
Amphetamine-Dextroamphetamine (Adderall) 1

Show all 14 treatments patients report switching to

Last updated:

28 patient evaluations for Selegiline

Sep 13, 2018 (Started Jan 04, 2007)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 15 mg Daily
Advice & Tips: It has previously been beneficial, but was diminishing with worsening familial stress and life stress Dr increased it to 15 mg/ dAY and I hAVE BEEN ABLE TO DECREASE rYTARY DAILY DOSE.
Cost: $200+ monthly
Side effects: skin irritation

Jun 25, 2014 (Started Jan 04, 2007)

  • Effectiveness
    Major (for depressed mood)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (skin irritation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 9 mg/24 hr Daily
Advice & Tips: Be careful with processed or preserved(like vinegar, red wine)
Cost: $50-99 monthly
Side effects: skin irritation

Dec 21, 2010 (Started Jan 04, 2007)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (skin irritation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg/24 hr All the time (24/7)
Cost: < $25 monthly
Side effects: skin irritation

Feb 18, 2009 (Started Jan 04, 2007)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg/24 hr All the time (24/7)
Cost: < $25 monthly
Side effects: skin irritation

Jan 17, 2009 (Started Jan 04, 2007)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg/24 hr All the time (24/7)
Cost: < $25 monthly
Side effects: skin irritation

Aug 19, 2008 (Started Jan 04, 2007)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg/24 hr All the time (24/7)
Advice & Tips: stick with it
Cost: < $25 monthly
Side effects: skin irritation

  • 2 helpful marks

Jan 15, 2014 (Started May 01, 2005)

  • Effectiveness
    Can't tell (for Other)
  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: Daily

  • 0 helpful marks

Jan 9, 2014 (Started Oct 07, 2008)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Feb 13, 2012 (Started Oct 07, 2008)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 28 patient evaluations for Selegiline