What is Promethazine?

Category: Prescription Drugs

Most popular types: Phenergan Promethegan Phenadoz Show all

false

See also: Promethazine DM

Promethazine is an antiemetic and antihistamine. It is used to relieve the symptoms of allergic reactions, nausea, motion sickness. It is also use as a sedative, as adjunctive therapy for postoperative pain, anesthetic and anaphylactic reactions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Nausea 268 80
Gastroparesis 52 13
Migraine headaches 39 16
Insomnia 18 5
Migraine 12 9

Show all 60 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 11
Moderate 33
Mild 62
None 76

Commonly reported side effects and conditions associated with Promethazine

Side effect Patients Percentage
Drowsiness 35
Sleepiness 10
Excessive daytime sleepiness (somnolence) 6
Fatigue 6
Tiredness 5
Dry mouth 3

Show all 38 reported side effects

Dosages

Based on patients currently taking Promethazine

Dosage Patients Percentage
25mg as needed 21
25mg/mL as needed 5
25 mg daily 4
12.5mg as needed 3
50 mg daily 2
25 mg three times daily 2
12.5 mg four times daily 1
25 mg twice daily 1
75 mg daily 1
312.5 mg twice daily 1

See all 14 dosages

Why patients stopped taking Promethazine

Multiple reasons could be selected

Reason Patients Percentage
Course of treatment ended 35
Doctor's advice 30
Other 27
Did not seem to work 26
Side effects too severe 23
Change in health plan coverage 3
Expense 1
See all 119 patients who've stopped taking Promethazine

Duration

Currently taking Promethazine

Duration Patients Percentage
1 - 6 months 2
6 months - 1 year 1
1 - 2 years 1
2 - 5 years 7
5 - 10 years 18
10 years or more 16

Stopped taking Promethazine

Duration Patients Percentage
Less than 1 month 34
1 - 6 months 20
6 months - 1 year 15
1 - 2 years 16
2 - 5 years 20
5 - 10 years 9
10 years or more 7
Adherence
Adherence Evaluations Percentage
Always 115
Usually 32
Sometimes 28
Never taken as prescribed 7
Burden
Burden Evaluations Percentage
Very hard to take 3
Somewhat hard to take 11
A little hard to take 20
Not at all hard to take 148
Cost per month
Cost per month Evaluations Percentage
$200+ 3
$100-199 0
$50-99 0
$25-49 5
< $25 92
Not specified 82

What people switch to and from

Patients started taking Promethazine after stopping:

Treatment Patients Percentage
Ondansetron (Zofran) 14
Meclizine (Meclizine OTC) 2
Carbamazepine (Tegretol) 1
Gabapentin (Neurontin) 1
Prochlorperazine (Compazine) 1

Show all 7 treatments patients report switching from

Patients stopped taking Promethazine and switched to:

Treatment Patients Percentage
Ondansetron (Zofran) 22
Prochlorperazine (Compazine) 3
Cetirizine-pseudoephedrine (Zyrtec-D) 1
Medical marijuana (Cannabidiol/Tetrahydrocannabinol Balanced Mixture) 1
Metoclopramide (Reglan) 1

Show all 7 treatments patients report switching to

Last updated:

19 patient evaluations for Promethazine

Apr 6, 2018 (Started Mar 01, 2017)

  • Effectiveness
    Major (for nausea)
  • Side effects
    Mild (restless legs syndrome, drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks

Feb 15, 2016 (Started Sep 26, 2015)

  • Effectiveness
    Major (for nausea and vomiting)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks

Dec 1, 2015 (Started Feb 24, 2011)

  • Effectiveness
    None (for multiple sclerosis)
  • Effectiveness
    Moderate (for nausea)
  • Effectiveness
    Moderate (for nausea and vomiting)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 50 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 19 patient evaluations for Promethazine