What is Pramipexole?

Category: Prescription Drugs

Most popular types: Mirapex Mirapex ER Sifrol Show all

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Pramipexole is an anti-Parkinson's agent that is used to treat symptoms of Parkinson's Disease, such as stiffness, tremors, muscle spasms, and poor muscle control and for moderate to severe primary restless legs syndrome. It may also be used for the treatment of depression.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 1120 655
Restless legs syndrome 281 152
Restless feeling in legs 185 80
Tremor(s) 50 42
Stiffness/spasticity 36 30
Periodic limb movement disorder 23 13

Show all 89 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 142
Moderate 228
Mild 232
None 332

Commonly reported side effects and conditions associated with Pramipexole

Side effect Patients Percentage
Drowsiness 88
Weight gain 54
Nausea 48
Insomnia 38
Vivid dreams 29
Excessive daytime sleepiness (somnolence) 26

Show all 184 reported side effects

Dosages

Based on patients currently taking Pramipexole

Dosage Patients Percentage
3 mg daily 9
0.25 mg daily 7
1.5 mg daily 7
0.125 mg daily 6
0.5 mg daily 6
1 mg three times daily 6
0.5 mg three times daily 5
1 mg daily 4
0.75 mg daily 3
2 mg daily 3

See all 37 dosages

Why patients stopped taking Pramipexole

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 266
Doctor's advice 149
Did not seem to work 137
Other 61
Expense 29
Personal research 25
Change in health plan coverage 11
Course of treatment ended 10
See all 514 patients who've stopped taking Pramipexole

Duration

Currently taking Pramipexole

Duration Patients Percentage
1 - 6 months 1
6 months - 1 year 3
1 - 2 years 8
2 - 5 years 23
5 - 10 years 27
10 years or more 28

Stopped taking Pramipexole

Duration Patients Percentage
Less than 1 month 62
1 - 6 months 109
6 months - 1 year 84
1 - 2 years 96
2 - 5 years 120
5 - 10 years 42
10 years or more 7
Adherence
Adherence Evaluations Percentage
Always 738
Usually 136
Sometimes 17
Never taken as prescribed 43
Burden
Burden Evaluations Percentage
Very hard to take 34
Somewhat hard to take 104
A little hard to take 183
Not at all hard to take 613
Cost per month
Cost per month Evaluations Percentage
$200+ 35
$100-199 20
$50-99 54
$25-49 120
< $25 351
Not specified 354

What people switch to and from

Patients started taking Pramipexole after stopping:

Treatment Patients Percentage
Ropinirole (Requip) 25
Carbidopa-Levodopa (Sinemet) 16
Rotigotine (Neupro Patch) 10
Rasagiline (Azilect) 6
Amantadine (Symmetrel) 4

Show all 18 treatments patients report switching from

Patients stopped taking Pramipexole and switched to:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 29
Ropinirole (Requip) 22
Rotigotine (Neupro Patch) 12
Amantadine (Symmetrel) 6
Rasagiline (Azilect) 4

Show all 21 treatments patients report switching to

Last updated:

90 patient evaluations for Pramipexole

Jun 26, 2020 (Started Oct 19, 2008)

  • Effectiveness
    Major (for restless legs syndrome)
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (excessive daytime sleepiness (somnolence), weight gain, drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1.5 mg Daily
Cost: < $25 monthly
Side effects: weight gain, drowsiness, excessive daytime sleepiness (somnolence)

Mar 1, 2020 (Started Oct 19, 2008)

  • Effectiveness
    Major (for restless legs syndrome)
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), weight gain, drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1.5 mg Daily
Cost: < $25 monthly
Side effects: weight gain, drowsiness, excessive daytime sleepiness (somnolence)

Jan 12, 2017 (Started Oct 19, 2008)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), weight gain, drowsiness)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 1.5 mg Daily
Advice & Tips: The Mirapex IR is still working well for me. I use it for restless legs & as dopamine agonist for PD.
Cost: < $25 monthly
Side effects: weight gain, drowsiness, excessive daytime sleepiness (somnolence)

Apr 20, 2016 (Started Oct 19, 2008)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), weight gain, drowsiness)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 1.5 mg Daily
Cost: < $25 monthly
Side effects: weight gain, drowsiness, excessive daytime sleepiness (somnolence)

Nov 10, 2014 (Started Oct 19, 2008)

  • Effectiveness
    Major (for restless legs syndrome)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), weight gain, drowsiness)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 1.5 mg Daily
Advice & Tips: For a brief time I took this in its XR formula with great success. It seemed not to cause as much daytime somnolence in this form. But it was a 4th Tier drug and my cost for 3 months was $600. I tried it for 3 months & then went to the immediate release. I am struggling with drowsiness & trying to remember the noon dose.
Cost: < $25 monthly
Side effects: weight gain, drowsiness, excessive daytime sleepiness (somnolence)

Oct 14, 2011 (Started Oct 19, 2008)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), weight gain, drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 mg Daily
Cost: < $25 monthly
Side effects: weight gain, drowsiness, excessive daytime sleepiness (somnolence)

Mar 15, 2010 (Started Oct 19, 2008)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), weight gain, drowsiness)
  • Adherence
    Never taken as prescribed
  • Burden
    Very hard to take
Dosage: 1 mg Daily
Advice & Tips: It eliminates the restless legs syndrome I used to suffer with.
Cost: < $25 monthly
Side effects: weight gain, drowsiness, excessive daytime sleepiness (somnolence)

Jan 7, 2009 (Started Oct 19, 2008)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), weight gain, drowsiness)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 1 mg Daily
Cost: < $25 monthly
Side effects: weight gain, drowsiness, excessive daytime sleepiness (somnolence)

  • 0 helpful marks

Apr 11, 2018 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: same as above
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Nov 4, 2017 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (nausea and vomiting, gambling urges)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 0.5 mg Four times daily
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Aug 10, 2017 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (nausea and vomiting, gambling urges)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

May 25, 2017 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (nausea and vomiting, gambling urges)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: Eat crackers when taking it to help with nausea
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Jan 17, 2017 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (nausea and vomiting, gambling urges)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: Eat crackers before taking the drug
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Oct 10, 2016 (Started Oct 01, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: No problems
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Sep 14, 2016 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (nausea and vomiting, gambling urges)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: Eat crackers.
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Jul 10, 2016 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 0.5 mg Four times daily
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Sep 16, 2015 (Started Oct 01, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (nausea and vomiting, gambling urges)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: Eat crackers when taking it to help with nausea
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Jan 24, 2011 (Started Oct 01, 2004)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Severe (nausea and vomiting, gambling urges)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3.5 mg Daily
Advice & Tips: Severly vomiting. Stopped the drug.
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Aug 26, 2008 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (gambling urges)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 1.5 mg Daily
Advice & Tips: Good medicine for Parkinsons, but can make you want to gamble.
Cost: $25-49 monthly
Side effects: gambling urges, nausea and vomiting

  • 0 helpful marks

Aug 24, 2017 (Started Jan 15, 2012)

  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.75 mg Daily

Aug 27, 2016 (Started Jan 15, 2012)

  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.75 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 90 patient evaluations for Pramipexole