What is Nortriptyline?

Category: Prescription Drugs

Most popular types: Pamelor Aventyl APO-Nortriptyline Show all

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See also: Gabapentin-Nortriptyline

Nortriptyline is a tricyclic antidepressant used in the treatment of depression. It is also used for chronic pain, anxiety disorders, bedwetting in children, attention-deficit/hyperactivity disorder (ADHD); and as an adjunctive therapy for smoking cessation.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Pain 258 114
Fibromyalgia 235 103
Depressed mood 182 98
Migraine headaches 83 44
Nerve pain (neuralgia) 42 16

Show all 148 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 71
Moderate 127
Mild 118
None 141

Commonly reported side effects and conditions associated with Nortriptyline

Side effect Patients Percentage
Dry mouth 59
Weight gain 33
Constipation 22
Fatigue 19
Drowsiness 17
Tachycardia (fast heart rate) 12

Show all 147 reported side effects

Dosages

Based on patients currently taking Nortriptyline

Dosage Patients Percentage
50 mg daily 22
75 mg daily 14
25 mg daily 11
10 mg daily 9
20 mg daily 5
100 mg daily 5
30 mg daily 3
25 mg three times daily 2
150 mg daily 2
10 mg/5 mL daily 1

See all 20 dosages

Why patients stopped taking Nortriptyline

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 147
Did not seem to work 141
Doctor's advice 94
Other 56
Personal research 17
Course of treatment ended 15
Expense 5
Change in health plan coverage 3
See all 338 patients who've stopped taking Nortriptyline

Duration

Currently taking Nortriptyline

Duration Patients Percentage
1 - 6 months 3
6 months - 1 year 1
1 - 2 years 8
2 - 5 years 33
5 - 10 years 19
10 years or more 22

Stopped taking Nortriptyline

Duration Patients Percentage
Less than 1 month 77
1 - 6 months 105
6 months - 1 year 47
1 - 2 years 41
2 - 5 years 50
5 - 10 years 11
10 years or more 11
Adherence
Adherence Evaluations Percentage
Always 380
Usually 53
Sometimes 7
Never taken as prescribed 17
Burden
Burden Evaluations Percentage
Very hard to take 10
Somewhat hard to take 23
A little hard to take 65
Not at all hard to take 359
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 2
$25-49 8
< $25 252
Not specified 195

What people switch to and from

Patients started taking Nortriptyline after stopping:

Treatment Patients Percentage
Amitriptyline (Elavil) 34
Duloxetine (Cymbalta) 6
Pregabalin (Lyrica) 5
Escitalopram (Lexapro) 4
Gabapentin (Neurontin) 4

Show all 38 treatments patients report switching from

Patients stopped taking Nortriptyline and switched to:

Treatment Patients Percentage
Gabapentin (Neurontin) 8
Amitriptyline (Elavil) 5
Duloxetine (Cymbalta) 4
Pregabalin (Lyrica) 4
Milnacipran (Savella) 2

Show all 32 treatments patients report switching to

Last updated:

38 patient evaluations for Nortriptyline

Jun 22, 2016 (Started Jun 19, 2016)

  • Effectiveness
    None (for peripheral neuropathy)
  • Effectiveness
    None (for TMJ (temporomandibular joint) pain)
  • Effectiveness
    None (for vulvodynia)
  • Side effects
    Severe (tachycardia (fast heart rate), constipation, heat intolerance, sweating, nausea, flatulence)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Apr 6, 2016 (Started Dec 15, 2015)

  • Effectiveness
    Moderate (for drooling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg/5 mL Daily

  • 0 helpful marks

Aug 7, 2015 (Started Jun 30, 2012)

  • Effectiveness
    Can't tell (for depressed mood)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for nerve pain (neuralgia))
  • Effectiveness
    Slight (for pain)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks
Last updated:
Showing 3 of 38 patient evaluations for Nortriptyline