What is Nortriptyline?

Category: Prescription Drugs

Most popular types: Pamelor Aventyl APO-Nortriptyline Show all

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See also: Gabapentin-Nortriptyline

Nortriptyline is a tricyclic antidepressant used in the treatment of depression. It is also used for chronic pain, anxiety disorders, bedwetting in children, attention-deficit/hyperactivity disorder (ADHD); and as an adjunctive therapy for smoking cessation.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Pain 257 116
Fibromyalgia 234 103
Depressed mood 183 100
Migraine headaches 83 44
Nerve pain (neuralgia) 41 15

Show all 143 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 73
Moderate 127
Mild 117
None 141

Commonly reported side effects and conditions associated with Nortriptyline

Side effect Patients Percentage
Dry mouth 58
Weight gain 34
Constipation 21
Fatigue 18
Drowsiness 17
Tachycardia (fast heart rate) 12

Show all 146 reported side effects

Dosages

Based on patients currently taking Nortriptyline

Dosage Patients Percentage
50 mg daily 15
75 mg daily 14
25 mg daily 13
10 mg daily 8
30 mg daily 6
150 mg daily 6
20 mg daily 4
100 mg daily 4
25 mg three times daily 3
10 mg/5 mL daily 1

See all 18 dosages

Why patients stopped taking Nortriptyline

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 147
Did not seem to work 139
Doctor's advice 93
Other 56
Personal research 17
Course of treatment ended 15
Expense 5
Change in health plan coverage 3
See all 337 patients who've stopped taking Nortriptyline

Duration

Currently taking Nortriptyline

Duration Patients Percentage
1 - 6 months 2
6 months - 1 year 5
1 - 2 years 9
2 - 5 years 33
5 - 10 years 17
10 years or more 19

Stopped taking Nortriptyline

Duration Patients Percentage
Less than 1 month 76
1 - 6 months 104
6 months - 1 year 48
1 - 2 years 41
2 - 5 years 49
5 - 10 years 11
10 years or more 11
Adherence
Adherence Evaluations Percentage
Always 381
Usually 53
Sometimes 7
Never taken as prescribed 17
Burden
Burden Evaluations Percentage
Very hard to take 10
Somewhat hard to take 24
A little hard to take 65
Not at all hard to take 359
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 2
$25-49 8
< $25 252
Not specified 196

What people switch to and from

Patients started taking Nortriptyline after stopping:

Treatment Patients Percentage
Amitriptyline (Elavil) 33
Duloxetine (Cymbalta) 6
Pregabalin (Lyrica) 5
Escitalopram (Lexapro) 4
Gabapentin (Neurontin) 4

Show all 36 treatments patients report switching from

Patients stopped taking Nortriptyline and switched to:

Treatment Patients Percentage
Gabapentin (Neurontin) 7
Amitriptyline (Elavil) 5
Duloxetine (Cymbalta) 4
Pregabalin (Lyrica) 4
Milnacipran (Savella) 2

Show all 32 treatments patients report switching to

Last updated:

38 patient evaluations for Nortriptyline

Jun 22, 2016 (Started Jun 19, 2016)

  • Effectiveness
    None (for peripheral neuropathy)
  • Effectiveness
    None (for TMJ (temporomandibular joint) pain)
  • Effectiveness
    None (for vulvodynia)
  • Side effects
    Severe (tachycardia (fast heart rate), constipation, heat intolerance, sweating, nausea, flatulence)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Apr 6, 2016 (Started Dec 15, 2015)

  • Effectiveness
    Moderate (for drooling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg/5 mL Daily

  • 0 helpful marks

Aug 7, 2015 (Started Jun 30, 2012)

  • Effectiveness
    Can't tell (for depressed mood)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for nerve pain (neuralgia))
  • Effectiveness
    Slight (for pain)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks
Last updated:
Showing 3 of 38 patient evaluations for Nortriptyline