What is Nitrofurantoin?

Category: Prescription Drugs

Most popular types: Macrobid Macrodantin Nitrofurantoin-Macro Show all

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Nitrofurantoin is an antibiotic that is used to prevent and treat urinary tract infections caused by susceptible strains of E. coli, S. aureus, Enterococcus, Klebsiella, and Enterobacter.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bladder problems 58 14
Prevent infection 58 33
Urinary tract infection 18 15
Vesicoureteral reflux 6 0
Frequent urination 3 2

Show all 17 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 1
Moderate 10
Mild 14
None 73

Commonly reported side effects and conditions associated with Nitrofurantoin

Side effect Patients Percentage
Diarrhea 3
Abdominal cramps 1
Abnormal urine color 1
Chronic diarrhea 1
Drowsiness 1
Excessive daytime sleepiness (somnolence) 1

Show all 15 reported side effects

Dosages

Based on patients currently taking Nitrofurantoin

Dosage Patients Percentage
50 mg daily 3
100 mg daily 2
25 mg daily 1
100 mg every other day 1
25-75 mg twice daily 1
100 mg twice daily 1
100mg as needed 1

Why patients stopped taking Nitrofurantoin

Multiple reasons could be selected

Reason Patients Percentage
Course of treatment ended 53
Doctor's advice 26
Other 10
Did not seem to work 8
Side effects too severe 5
Personal research 2
See all 86 patients who've stopped taking Nitrofurantoin

Duration

Currently taking Nitrofurantoin

Duration Patients Percentage
1 - 6 months 2
1 - 2 years 1
2 - 5 years 3
5 - 10 years 1
10 years or more 3

Stopped taking Nitrofurantoin

Duration Patients Percentage
Less than 1 month 40
1 - 6 months 9
6 months - 1 year 5
1 - 2 years 12
2 - 5 years 12
5 - 10 years 5
10 years or more 2
Adherence
Adherence Evaluations Percentage
Always 87
Usually 6
Sometimes 3
Never taken as prescribed 2
Burden
Burden Evaluations Percentage
Very hard to take 0
Somewhat hard to take 7
A little hard to take 10
Not at all hard to take 81
Cost per month
Cost per month Evaluations Percentage
$200+ 5
$100-199 0
$50-99 3
$25-49 3
< $25 41
Not specified 46

What people switch to and from

Patients started taking Nitrofurantoin after stopping:

Treatment Patients Percentage
Cephalexin (Keflex) 3
Sulfamethoxazole-Trimethoprim (cotrimoxazole) (Bactrim) 3
Ciprofloxacin (Cipro) 2
Amoxicillin (Amoxil) 1
Cefuroxime (Ceftin) 1

Show all 6 treatments patients report switching from

Patients stopped taking Nitrofurantoin and switched to:

Treatment Patients Percentage
Fosfomycin (Monurol) 2
Amoxicillin (Amoxil) 1
Bumetanide (Bumex) 1
Cephalexin (Keflex) 1
Ciprofloxacin (Cipro) 1

Show all 8 treatments patients report switching to

Last updated:

12 patient evaluations for Nitrofurantoin

Aug 13, 2018 (Started Aug 05, 2018)

  • Effectiveness
    Major (for UTI symptoms)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Sep 28, 2016 (Started Apr 06, 2015)

  • Effectiveness
    Major (for Prevent infection)
  • Effectiveness
    Moderate (for UTI symptoms)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 50 mg Daily

  • 0 helpful marks

Sep 7, 2016 (Started Jul 19, 2013)

  • Effectiveness
    Major (for neurogenic bladder)
  • Side effects
    Moderate (destroys gut biome)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 75 mg M,W,F
Advice & Tips: My urologist says long-term Macrobid can cause pulmonary fibrosis. to me it didn't make sense to destroy my gut biome every day
Cost: $50-99 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 12 patient evaluations for Nitrofurantoin