What is Modafinil?

Category: Prescription Drugs

Most popular types: Provigil Alertec Modiodal Show all

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Modafinil is stimulant used to improve wakefulness in patients narcolepsy and shift work sleep disorder or as an adjunctive therapy for obstructive sleep apnea. It may also be used for attention-deficit/hyperactivity disorder and to treat fatigue in MS and other disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fatigue 1536 731
Multiple sclerosis 915 439
Excessive daytime sleepiness (somnolence) 535 373
Narcolepsy 108 59
Brain fog 82 54

Show all 86 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 73
Moderate 157
Mild 267
None 656

Commonly reported side effects and conditions associated with Modafinil

Side effect Patients Percentage
Jittery feeling 57
Headaches 55
Dry mouth 51
Anxious mood 36
Tachycardia (fast heart rate) 30
Irritability 21

Show all 153 reported side effects

Dosages

Based on patients currently taking Modafinil

Dosage Patients Percentage
200 mg daily 40
100 mg daily 27
400 mg daily 11
200 mg twice daily 9
100 mg twice daily 4
300 mg daily 4
100mg as needed 3
200mg as needed 2
1 tablet(s) daily 1
50 mg weekly 1

See all 21 dosages

Why patients stopped taking Modafinil

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 296
Other 207
Side effects too severe 200
Expense 181
Doctor's advice 121
Change in health plan coverage 94
Personal research 35
Course of treatment ended 19
See all 891 patients who've stopped taking Modafinil

Duration

Currently taking Modafinil

Duration Patients Percentage
1 - 6 months 3
6 months - 1 year 2
1 - 2 years 9
2 - 5 years 16
5 - 10 years 36
10 years or more 48

Stopped taking Modafinil

Duration Patients Percentage
Less than 1 month 134
1 - 6 months 183
6 months - 1 year 127
1 - 2 years 149
2 - 5 years 199
5 - 10 years 80
10 years or more 28
Adherence
Adherence Evaluations Percentage
Always 784
Usually 229
Sometimes 99
Never taken as prescribed 41
Burden
Burden Evaluations Percentage
Very hard to take 36
Somewhat hard to take 64
A little hard to take 145
Not at all hard to take 908
Cost per month
Cost per month Evaluations Percentage
$200+ 89
$100-199 54
$50-99 141
$25-49 168
< $25 344
Not specified 357

What people switch to and from

Patients started taking Modafinil after stopping:

Treatment Patients Percentage
Methylphenidate (Ritalin) 26
Armodafinil (Nuvigil) 22
Amphetamine-Dextroamphetamine (Adderall) 16
Amantadine (Symmetrel) 11
Amitriptyline (Elavil) 2

Show all 21 treatments patients report switching from

Patients stopped taking Modafinil and switched to:

Treatment Patients Percentage
Armodafinil (Nuvigil) 35
Amphetamine-Dextroamphetamine (Adderall) 33
Methylphenidate (Ritalin) 11
Lisdexamfetamine (Vyvanse) 5
Dextroamphetamine (Dexedrine) 4

Show all 9 treatments patients report switching to

Last updated:

132 patient evaluations for Modafinil

Jan 10, 2019 (Started Apr 06, 2006)

  • Effectiveness
    Slight (for fatigue)
  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Take provigil mo later than noon. I took it once around 3 pm then I couldn’t get to sleep until ~ 4am!

Dec 2, 2015 (Started Apr 06, 2006)

  • Effectiveness
    Major (for fatigue)
  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Provigil gives me energy to do my daily chores i.e. fixing meals, laundry, showering. I have no side efffects! The generic modafinil is the same as Provigil and much less expensive!

  • 0 helpful marks

May 19, 2018 (Started Aug 31, 2010)

  • Effectiveness
    None (for Parkinson's disease)
  • Effectiveness
    None (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: NOW THAT I HAVE PD AND SENSORY NEUROPATHY I AM ALWAY S TIRED AND IN PAIN.
Cost: $25-49 monthly

Dec 28, 2016 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: $25-49 monthly

Aug 11, 2015 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I GET TIRED EVERYDAY STILL, BUT I DON'T ALWAYS NAP LIKE I USED TO.
Cost: $25-49 monthly

Aug 11, 2014 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: It is still working well, as my napping and dozing has decreased quite a bit. Thumbs Up to Provigil!!
Cost: $25-49 monthly

Jul 14, 2012 (Started Aug 31, 2010)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: DEFINITELY HELPS SO I'M NOT ALWAYS DOZING OFF.
Cost: $25-49 monthly

Dec 1, 2011 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: The insurance company stopped paying for Provogil. It took a month to get it approved.
Cost: $25-49 monthly

Nov 15, 2011 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I get very tired and could sleep all day. I was on Provigil, but then the insurance company denied refills. It took a month to get the insurance company to approve it.
Cost: $25-49 monthly

Aug 1, 2011 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I was on Provigil because e I was sleeping all the time. Then insurance company denied my prescription. It took one month to get me back on it.
Cost: $25-49 monthly

Aug 1, 2010 (Started Aug 31, 2010)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Without this medication, I sleep on & off all day, and I am constantly weak & tired. I don't feel like doing anything. My insurance company stopped paying for it for 1 month while I appealed their decision. I won the appeal and I thank God I was able to take it again.
Cost: $25-49 monthly

  • 1 helpful mark

Feb 21, 2018 (Started Apr 01, 2009)

  • Effectiveness
    Moderate (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: One pill keeps me awake and alert until mid-day. That's what I expected. It's easy to adhere to and does't cause me any side affects.

  • 0 helpful marks
Last updated:
Showing 3 of 132 patient evaluations for Modafinil