What is Mitoxantrone?

Category: Prescription Drugs

Most popular types: Novantrone

false

See also: FCMR protocol

Mitoxantrone is an antineoplastic agent used in the treatment of acute nonlymphocytic leukemia, prostate cancer, secondary progressive or relapsing-remitting MS. It may also be used for certain lymphomas, certain adult and pediatric leukemias, myelodysplastic syndrome, breast cancer and sarcoma.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 1154 80
Weakness in leg(s) 6 3
Improve mobility 4 5
General health 2 0
Neuromyelitis optica 2 0

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 18
Moderate 24
Mild 25
None 19

Commonly reported side effects and conditions associated with Mitoxantrone

Side effect Patients Percentage
Nausea 15
Tiredness 14
Hair loss 12
Generalized weakness (asthenia) 6
Headaches 6
Pain 6

Show all 30 reported side effects

Dosages

Based on patients currently taking Mitoxantrone

Dosage Patients Percentage
2 mg every 3 months 1
20 mg every 3 months 1
1000 mg every 6 months 1

Why patients stopped taking Mitoxantrone

Multiple reasons could be selected

Reason Patients Percentage
Course of treatment ended 106
Doctor's advice 79
Did not seem to work 59
Side effects too severe 57
Other 25
Personal research 6
Expense 4
Change in health plan coverage 1
See all 252 patients who've stopped taking Mitoxantrone

Duration

Currently taking Mitoxantrone

Duration Patients Percentage
1 - 2 years 1
2 - 5 years 1
5 - 10 years 1
10 years or more 1

Stopped taking Mitoxantrone

Duration Patients Percentage
Less than 1 month 30
1 - 6 months 46
6 months - 1 year 52
1 - 2 years 52
2 - 5 years 46
5 - 10 years 5
10 years or more 4
Adherence
Adherence Evaluations Percentage
Always 75
Usually 5
Sometimes 0
Never taken as prescribed 6
Burden
Burden Evaluations Percentage
Very hard to take 10
Somewhat hard to take 22
A little hard to take 21
Not at all hard to take 33
Cost per month
Cost per month Evaluations Percentage
$200+ 4
$100-199 4
$50-99 0
$25-49 2
< $25 25
Not specified 51

What people switch to and from

Patients started taking Mitoxantrone after stopping:

Treatment Patients Percentage
Interferon beta-1a IM Injection (Avonex) 2
Interferon beta-1b SubQ Injection (Betaseron) 2
Natalizumab (Tysabri) 2
Glatiramer acetate (Copaxone) 1
Interferon beta-1a SubQ injection (Rebif) 1

Show all 6 treatments patients report switching from

Patients stopped taking Mitoxantrone and switched to:

Treatment Patients Percentage
Glatiramer acetate (Copaxone) 3
Natalizumab (Tysabri) 3
Fingolimod (Gilenya) 1
Naltrexone (Low Dose Naltrexone (LDN)) 1
Stem Cell Transplant (Autologous Stem Cell Transplant) 1
Last updated:

20 patient evaluations for Mitoxantrone

Mar 15, 2012 (Started Jan 05, 2011)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Severe (It affected my heart, heart problems)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Advice & Tips: Just make sure your Dr does regular blood test and Echocardiograms to keep a close watch on you hearts function.
Cost: < $25 monthly

  • 0 helpful marks

Jun 16, 2011 (Started Feb 05, 2011)

  • Effectiveness
    Slight (for multiple sclerosis)
  • Side effects
    Moderate (fatigue)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 20 mg Every 3 months
Advice & Tips: When you start this treatment program. You have a sonogram done on your heart. blood test for a baseline. Then you start treatment after treatment a week later a blood test then a two weeks. Then before your next round of treatment blood test and another heart sonogram.
Cost: < $25 monthly
Side effects: fatigue

  • 1 helpful mark

May 18, 2011 (Started Apr 04, 2008)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Severe (nausea)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 5 mg Every 3 months
Advice & Tips: This was a miracle drug for me. It is IV chemotherapy treatment for last ditch effort in treating MS. It turned my world around to where I felt like a functioning human again. It virtually stopped my exacerbations and I was able to walk on my own for the first time in seven years. The side effects were terrible for about two weeks after treatment. Vomiting and nausea, with lots of weakness and I lost my hair. The sad thing is that you can only take so many treatments in a lifetime. Now that mine are over I am going downhi again.
Side effects: nausea

  • 2 helpful marks
Last updated:
Showing 3 of 20 patient evaluations for Mitoxantrone