What is Methylprednisolone?

Category: Prescription Drugs

Most popular types: Solu-Medrol Infusion Solu-Medrol Methylprednisolone Infusion Show all

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Methylprednisolone is a synthetic corticosteroid drug used primarily as an anti-inflammatory or immunosuppressant agent for diseases of hematologic, allergic, inflammatory, neoplastic, and autoimmune origin; also for graft-versus-host disease.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 567 362
Prevent organ rejection 72 18
Pain 70 43
Stiffness/spasticity 67 31
Optic nerve inflammation (optic neuritis) 44 31

Show all 268 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 141
Moderate 304
Mild 267
None 204

Commonly reported side effects and conditions associated with Methylprednisolone

Side effect Patients Percentage
Insomnia 76
Metallic taste in mouth 70
Weight gain 60
Increased appetite 45
Headaches 40
Change in taste 39

Show all 248 reported side effects

Dosages

Based on patients currently taking Methylprednisolone

Dosage Patients Percentage
1 g daily 4
4 mg daily 2
8 mg daily 2
12 mg daily 2
4 mg three times daily 2
3 x 1,000 mg daily 2
40 mg every 6 months 2
4mg as needed 2
1 g monthly 1
50 mg every 8 weeks 1

See all 36 dosages

Why patients stopped taking Methylprednisolone

Multiple reasons could be selected

Reason Patients Percentage
Course of treatment ended 991
Doctor's advice 172
Did not seem to work 89
Side effects too severe 84
Other 75
Change in health plan coverage 9
Personal research 9
Expense 4
See all 1239 patients who've stopped taking Methylprednisolone

Duration

Currently taking Methylprednisolone

Duration Patients Percentage
Less than 1 month 2
1 - 6 months 2
6 months - 1 year 3
1 - 2 years 5
2 - 5 years 15
5 - 10 years 11
10 years or more 9

Stopped taking Methylprednisolone

Duration Patients Percentage
Less than 1 month 854
1 - 6 months 131
6 months - 1 year 82
1 - 2 years 69
2 - 5 years 82
5 - 10 years 49
10 years or more 33
Adherence
Adherence Evaluations Percentage
Always 781
Usually 54
Sometimes 40
Never taken as prescribed 41
Burden
Burden Evaluations Percentage
Very hard to take 64
Somewhat hard to take 214
A little hard to take 262
Not at all hard to take 376
Cost per month
Cost per month Evaluations Percentage
$200+ 49
$100-199 25
$50-99 35
$25-49 26
< $25 344
Not specified 437

What people switch to and from

Patients started taking Methylprednisolone after stopping:

Treatment Patients Percentage
Prednisone (Deltasone) 17
Dimethyl fumarate (Tecfidera) 2
Intravenous Immunoglobulin (IVIG) (Gammaglobulin (IVIg)) 2
Methotrexate (Trexall) 2
Methylprednisolone (Solu-Medrol Infusion) 2

Show all 18 treatments patients report switching from

Patients stopped taking Methylprednisolone and switched to:

Treatment Patients Percentage
Prednisone (Deltasone) 9
Intravenous Immunoglobulin (IVIG) (Gammaglobulin (IVIg)) 3
Corticotropin (Acthar Gel HP) 2
Hydroxychloroquine (Plaquenil) 2
Rituximab (Rituxan) 2

Show all 22 treatments patients report switching to

Last updated:

111 patient evaluations for Methylprednisolone

Oct 10, 2018 (Started Oct 11, 2018)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips: Strangely, this had practical no effect on me. The purpose was to boost Benepali, because Benepali had lost its effect little by little. Things got a little better after one week and lasted for about 6 weeks, but I don't know why. I will continue Benepali another 2 month.

  • 0 helpful marks

Mar 30, 2016 (Started Feb 17, 2010)

  • Effectiveness
    Can't tell (for relapse MS (exacerbation))
  • Side effects
    Mild (increased insomnia, generalized weakness (asthenia))
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Advice & Tips: 3 days of infusions for MS hugs and numbness.  Last infusion was April 1, 2016. Numbness already improved.  Weak and tired. Very hungry. 

Feb 17, 2010 (Started Feb 17, 2010)

  • Effectiveness
    Major (for relapse MS (exacerbation))
  • Side effects
    Mild (increased insomnia)
  • Adherence
    Never taken as prescribed
  • Burden
    A little hard to take
Dosage: 120 mg Daily
Advice & Tips: I was 3 days of IV infusion for "hug" spasms that didn't respond to medication. It did help, gradually but I felt awful by the 3rd treatment and it was difficult to work full time while undergoing this treatment.

  • 0 helpful marks

Nov 15, 2015 (Started Nov 15, 2015)

  • Effectiveness
    Moderate (for cervical dystonia (torticollis))
  • Side effects
    Mild (unrefreshing or poor sleep)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Eat while taking. Just don't eat too much.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 111 patient evaluations for Methylprednisolone