What is Methotrexate injections?

Category: Prescription Drugs

Most popular types: Intrathecal Methotrexate Metoject Otrexup Show all

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Methotrexate is an antineoplastic drug used in the treatment of cancer. Also used as an antirheumatic for rheumatoid arthritis. It may also be used in treatment of Crohn's disease, ectopic pregnancy, or MS. It is given by mouth, by injection, via IV or intrathecally.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid arthritis 25 11
Systemic lupus erythematosus 9 4
Psoriatic arthritis 5 2
Crohn's disease 3 1
Multiple sclerosis 2 2
Dermatomyositis 1 0

Show all 15 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 5
Moderate 7
Mild 10
None 3

Commonly reported side effects and conditions associated with Methotrexate injections

Side effect Patients Percentage
Nausea 8
Headaches 3
Joint pain 3
Mouth sores (ulcers) 3
Fatigue 2
Hair loss 2

Show all 22 reported side effects

Dosages

Based on patients currently taking Methotrexate injections

Dosage Patients Percentage
25 mg weekly 4
20 mg weekly 2
0.7 mL weekly 1
18.8 mg weekly 1
50 mg weekly 1
750 mg weekly 1

Why patients stopped taking Methotrexate injections

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 5
Did not seem to work 4
Doctor's advice 4
Change in health plan coverage 2
Other 1
Personal research 1
See all 11 patients who've stopped taking Methotrexate injections

Duration

Currently taking Methotrexate injections

Duration Patients Percentage
1 - 6 months 1
6 months - 1 year 2
1 - 2 years 1
2 - 5 years 7
5 - 10 years 1

Stopped taking Methotrexate injections

Duration Patients Percentage
Less than 1 month 2
1 - 6 months 2
6 months - 1 year 3
1 - 2 years 4
2 - 5 years 2
Adherence
Adherence Evaluations Percentage
Always 21
Usually 1
Sometimes 0
Never taken as prescribed 3
Burden
Burden Evaluations Percentage
Very hard to take 3
Somewhat hard to take 4
A little hard to take 10
Not at all hard to take 8
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 1
$50-99 0
$25-49 1
< $25 12
Not specified 11

What people switch to and from

Patients started taking Methotrexate injections after stopping:

Treatment Patients Percentage
Methotrexate (Trexall) 14
Hydroxychloroquine (Plaquenil) 2
Adalimumab (Humira) 1
Sulfasalazine (Salazopyrin) 1
Vitamin B12 Injection (Medivitan) 1

Patients stopped taking Methotrexate injections and switched to:

Treatment Patients Percentage
Adalimumab (Humira) 1
Azathioprine (Imuran) 1
Belimumab (Benlysta) 1
Methotrexate (Trexall) 1
Methylprednisolone (Solu-Medrol Infusion) 1

Show all 8 treatments patients report switching to

Last updated:
There are no evaluations for Methotrexate injections.