What is Mesalamine?

Category: Prescription Drugs

Most popular types: Pentasa Asacol Lialda Show all

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Mesalamine, a derivative of 5-aminosalicylic acid, is an anti-inflammatory agent. It can be used to treat ulcerative colitis and Crohn’s disease. It can be taken orally or applied rectally to help treat the inflammation associated with these conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Crohn's disease 262 108
Ulcerative colitis 196 104
Microscopic colitis 7 6
Diarrhea 5 5
Chronic diarrhea 3 2

Show all 22 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 10
Moderate 29
Mild 33
None 154

Commonly reported side effects and conditions associated with Mesalamine

Side effect Patients Percentage
Headaches 9
Diarrhea 7
Nausea 6
Hair loss 5
Fatigue 4
Abdominal bloating 2

Show all 70 reported side effects

Dosages

Based on patients currently taking Mesalamine

Dosage Patients Percentage
2 x 1,200 mg daily 2
1000 mg four times daily 2
4 x 1,200 mg daily 2
1.2 g daily 1
1.5 g daily 1
2.4 g daily 1
3 g daily 1
4 capsule(s) daily 1
4 g/60 mL daily 1
4.8 g daily 1

See all 27 dosages

Why patients stopped taking Mesalamine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 100
Doctor's advice 61
Side effects too severe 37
Other 28
Course of treatment ended 18
Expense 17
Change in health plan coverage 9
Personal research 9
See all 184 patients who've stopped taking Mesalamine

Duration

Currently taking Mesalamine

Duration Patients Percentage
1 - 6 months 1
6 months - 1 year 1
1 - 2 years 4
2 - 5 years 9
5 - 10 years 11
10 years or more 5

Stopped taking Mesalamine

Duration Patients Percentage
Less than 1 month 47
1 - 6 months 42
6 months - 1 year 21
1 - 2 years 25
2 - 5 years 20
5 - 10 years 20
10 years or more 19
Adherence
Adherence Evaluations Percentage
Always 169
Usually 40
Sometimes 7
Never taken as prescribed 10
Burden
Burden Evaluations Percentage
Very hard to take 15
Somewhat hard to take 33
A little hard to take 52
Not at all hard to take 126
Cost per month
Cost per month Evaluations Percentage
$200+ 17
$100-199 9
$50-99 11
$25-49 26
< $25 59
Not specified 104

What people switch to and from

Patients started taking Mesalamine after stopping:

Treatment Patients Percentage
Sulfasalazine (Salazopyrin) 14
Mesalamine (Pentasa) 6
Balsalazide (Colazal) 4
Azathioprine (Imuran) 2
Infliximab (Remicade) 2

Show all 9 treatments patients report switching from

Patients stopped taking Mesalamine and switched to:

Treatment Patients Percentage
Sulfasalazine (Salazopyrin) 8
Infliximab (Remicade) 7
Mesalamine (Pentasa) 6
Adalimumab (Humira) 4
Azathioprine (Imuran) 4

Show all 16 treatments patients report switching to

Last updated:

11 patient evaluations for Mesalamine

Jul 11, 2015 (Started Jan 15, 2014)

  • Effectiveness
    Moderate (for Crohn's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2.4 g Daily
Cost: $50-99 monthly

  • 0 helpful marks

May 31, 2014 (Started Oct 05, 2011)

  • Effectiveness
    Major (for gastrointestinal bleeding)
  • Effectiveness
    Major (for Crohn's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 3200 mg Daily
Advice & Tips: For some reason the Oregon Health Plan (new Obama-care insurance) does not cover Asacol HD 800mg TBEC. My recent flare-up may have been exacerbated because I ran out of the medication and couldn't get it refilled. For the last 2 weeks I have been paying out-of-pocket for it and it is EXPENSIVE. I will have to either find another medication option on Monday or work on the appeal process (which looks like a pain in the ass). Until then I will be paying out the whazoo for it because it is the only medication I know of that really can keep me in remission without noticeable side effects.
Cost: $200+ monthly

  • 0 helpful marks

Nov 24, 2012 (Started May 10, 2012)

  • Effectiveness
    Can't tell (for ulcerative colitis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 11 patient evaluations for Mesalamine