What is Mercaptopurine?

Category: Prescription Drugs

Most popular types: Purinethol

false

Mercaptopurine is an antineoplastic and immunosuppressant agent used for the treatment (maintenance and induction) of acute lymphoblastic leukemia. It is also used as a steroid-sparing agent for corticosteroid-dependent Crohn's disease and ulcerative colitis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Crohn's disease 44 21
Ulcerative colitis 8 7
Systemic lupus erythematosus 3 1
Autoimmune hepatitis 2 2
Acute lymphocytic leukemia 1 0

Show all 12 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 9
Moderate 10
Mild 4
None 12

Commonly reported side effects and conditions associated with Mercaptopurine

Side effect Patients Percentage
Nausea 6
Fatigue 5
Dizziness 3
Bruising 2
Headaches 2
Muscle and joint pain 2

Show all 31 reported side effects

Dosages

Based on patients currently taking Mercaptopurine

Dosage Patients Percentage
50 mg daily 1

Why patients stopped taking Mercaptopurine

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 14
Doctor's advice 10
Did not seem to work 8
Other 3
Course of treatment ended 2
Personal research 2
Change in health plan coverage 1
Expense 1
See all 29 patients who've stopped taking Mercaptopurine

Duration

Currently taking Mercaptopurine

Duration Patients Percentage
2 - 5 years 1

Stopped taking Mercaptopurine

Duration Patients Percentage
Less than 1 month 7
1 - 6 months 2
6 months - 1 year 2
1 - 2 years 3
2 - 5 years 5
5 - 10 years 8
10 years or more 2
Adherence
Adherence Evaluations Percentage
Always 26
Usually 6
Sometimes 0
Never taken as prescribed 3
Burden
Burden Evaluations Percentage
Very hard to take 3
Somewhat hard to take 1
A little hard to take 4
Not at all hard to take 27
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 1
$25-49 2
< $25 11
Not specified 21

What people switch to and from

Patients started taking Mercaptopurine after stopping:

Treatment Patients Percentage
Azathioprine (Imuran) 3
Prednisone (Deltasone) 3
Mesalamine (Pentasa) 2
Adalimumab (Humira) 1
Mesalamine (rectal) (Canasa) 1

Patients stopped taking Mercaptopurine and switched to:

Treatment Patients Percentage
Adalimumab (Humira) 4
Azathioprine (Imuran) 1
Budesonide (Pulmicort) 1
Infliximab (Remicade) 1
Mycophenolate mofetil (CellCept) 1

Show all 6 treatments patients report switching to

Last updated:

2 patient evaluations for Mercaptopurine

Feb 15, 2013 (Started Feb 15, 2013)

  • Effectiveness
    Slight (for Crohn's disease)
  • Side effects
    Severe (nausea and vomiting)
  • Adherence
    Never taken as prescribed
  • Burden
    Very hard to take
Dosage: 50 mg Daily
Advice & Tips: Possible pancreatitis. No-go.

  • 0 helpful marks

Dec 14, 2009 (Started Nov 20, 2009)

  • Effectiveness
    Can't tell (for ulcerative colitis)
  • Side effects
    Moderate (nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Side effects: nausea

  • 0 helpful marks
Last updated:
Showing 2 of 2 patient evaluations for Mercaptopurine