What is Melatonin?

Category: Supplements

Most popular types: Nature's Bounty Melatonin NatureMade Melatonin Melatonin Time Release Show all

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See also: Angelicalm Spray

Melatonin appears to be the primary sleep-regulating hormone of the body. It has been used by individuals suffering from insomnia, particularly when adjusting to shift-work cycles or jet lag. In the US Melatonin is available over-the-counter, however, it may require a prescription in some countries.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 503 233
Difficulty staying asleep 249 107
General health 24 8
Amyotrophic lateral sclerosis 21 6
Unrefreshing or poor sleep 21 8

Show all 78 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 15
Moderate 33
Mild 58
None 390

Commonly reported side effects and conditions associated with Melatonin

Side effect Patients Percentage
Drowsiness 14
Vivid dreams 7
Depressed mood 6
Grogginess in morning 6
Excessive daytime sleepiness (somnolence) 4
Fatigue 4

Show all 56 reported side effects

Dosages

Based on patients currently taking Melatonin

Dosage Patients Percentage
3 mg daily 39
10 mg daily 37
5 mg daily 30
1 mg daily 12
3mg as needed 9
5mg as needed 9
6 mg daily 6
9 mg daily 4
2 mg daily 3
12 mg daily 3

See all 39 dosages

Why patients stopped taking Melatonin

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 121
Other 81
Doctor's advice 43
Side effects too severe 29
Course of treatment ended 17
Personal research 17
Expense 15
See all 272 patients who've stopped taking Melatonin

Duration

Currently taking Melatonin

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 3
6 months - 1 year 7
1 - 2 years 21
2 - 5 years 69
5 - 10 years 60
10 years or more 27

Stopped taking Melatonin

Duration Patients Percentage
Less than 1 month 47
1 - 6 months 78
6 months - 1 year 48
1 - 2 years 44
2 - 5 years 46
5 - 10 years 18
10 years or more 6
Adherence
Adherence Evaluations Percentage
Always 300
Usually 108
Sometimes 73
Never taken as prescribed 15
Burden
Burden Evaluations Percentage
Very hard to take 5
Somewhat hard to take 16
A little hard to take 62
Not at all hard to take 413
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 1
$25-49 18
< $25 202
Not specified 275

What people switch to and from

Patients started taking Melatonin after stopping:

Treatment Patients Percentage
Trazodone (Desyrel) 2
Clonazepam (Klonopin) 1
Hydroxyzine (Vistaril) 1
Lorazepam (Ativan) 1
Quetiapine (Seroquel) 1

Show all 6 treatments patients report switching from

Patients stopped taking Melatonin and switched to:

Treatment Patients Percentage
Bupropion (Wellbutrin XL) 1
Clonidine (Catapres TTS patch) 1
Diazepam (Valium) 1
Metagenics NeuroCalm Sleep 1
Trazodone (Desyrel) 1
Last updated:

46 patient evaluations for Melatonin

Dec 1, 2017 (Started Sep 12, 2008)

  • Effectiveness
    None (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take

  • 0 helpful marks

Sep 20, 2017 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: After several nites of hideous nightmares and pummelling my husband in his sleep, I decided to increase the Melatonin to 5mg, 2 @hs. It has not made any difference so far.

Aug 18, 2017 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: My husband picked this up at the grocery store for me & he could only find it in gummy pills. I would prefer to take a pill but these gummy things do taste delicious. I take the melatonin to combat the REM Sleep Behavior D/O & it doesn't seem to lessen that problem (so far) but I think I am sleeping better. I will continue with the Melatonin in hopes it will help, and I haven't increased the dose as my doctor told me I can, so I can always try an added pill.

  • 0 helpful marks

Jan 31, 2017 (Started Nov 17, 2011)

  • Effectiveness
    Moderate (for difficulty staying asleep)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 46 patient evaluations for Melatonin