What is Melatonin?

Category: Supplements

Most popular types: Nature's Bounty Melatonin NatureMade Melatonin Melatonin Time Release Show all

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See also: Angelicalm Spray

Melatonin appears to be the primary sleep-regulating hormone of the body. It has been used by individuals suffering from insomnia, particularly when adjusting to shift-work cycles or jet lag. In the US Melatonin is available over-the-counter, however, it may require a prescription in some countries.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 508 241
Difficulty staying asleep 253 114
General health 24 8
Unrefreshing or poor sleep 22 10
Amyotrophic lateral sclerosis 21 6

Show all 78 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 15
Moderate 32
Mild 64
None 403

Commonly reported side effects and conditions associated with Melatonin

Side effect Patients Percentage
Drowsiness 14
Vivid dreams 7
Depressed mood 6
Grogginess in morning 5
Excessive daytime sleepiness (somnolence) 4
Fatigue 4

Show all 56 reported side effects

Dosages

Based on patients currently taking Melatonin

Dosage Patients Percentage
10 mg daily 32
3 mg daily 28
5 mg daily 25
1 mg daily 10
3mg as needed 7
10mg as needed 4
5mg as needed 4
6 mg daily 3
9 mg daily 3
2 5mg as needed 3

See all 29 dosages

Why patients stopped taking Melatonin

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 125
Other 82
Doctor's advice 43
Side effects too severe 29
Course of treatment ended 17
Personal research 17
Expense 15
See all 277 patients who've stopped taking Melatonin

Duration

Currently taking Melatonin

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 7
6 months - 1 year 6
1 - 2 years 21
2 - 5 years 46
5 - 10 years 40
10 years or more 19

Stopped taking Melatonin

Duration Patients Percentage
Less than 1 month 48
1 - 6 months 79
6 months - 1 year 48
1 - 2 years 46
2 - 5 years 46
5 - 10 years 18
10 years or more 7
Adherence
Adherence Evaluations Percentage
Always 312
Usually 107
Sometimes 77
Never taken as prescribed 18
Burden
Burden Evaluations Percentage
Very hard to take 5
Somewhat hard to take 16
A little hard to take 62
Not at all hard to take 431
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 1
$25-49 18
< $25 212
Not specified 283

What people switch to and from

Patients started taking Melatonin after stopping:

Treatment Patients Percentage
Trazodone (Desyrel) 2
Clonazepam (Klonopin) 1
Hydroxyzine (Vistaril) 1
Lorazepam (Ativan) 1
Quetiapine (Seroquel) 1

Show all 6 treatments patients report switching from

Patients stopped taking Melatonin and switched to:

Treatment Patients Percentage
Bupropion (Wellbutrin XL) 1
Clonidine (Catapres TTS patch) 1
Diazepam (Valium) 1
Metagenics NeuroCalm Sleep 1
Trazodone (Desyrel) 1
Last updated:

46 patient evaluations for Melatonin

Mar 1, 2020 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: I continue to take this medication b/c I feel it helps me sleep. However, I see no sign of abatement of nightmares or acting out my dreams in my sleep. I continue to clobber my husband, scream & kick him or just kick in the air.
Cost: < $25 monthly

Sep 20, 2017 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: After several nites of hideous nightmares and pummelling my husband in his sleep, I decided to increase the Melatonin to 5mg, 2 @hs. It has not made any difference so far.

Aug 18, 2017 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: My husband picked this up at the grocery store for me & he could only find it in gummy pills. I would prefer to take a pill but these gummy things do taste delicious. I take the melatonin to combat the REM Sleep Behavior D/O & it doesn't seem to lessen that problem (so far) but I think I am sleeping better. I will continue with the Melatonin in hopes it will help, and I haven't increased the dose as my doctor told me I can, so I can always try an added pill.

  • 0 helpful marks

Feb 24, 2020 (Started Jun 30, 2012)

  • Effectiveness
    Major (for insomnia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Taking one a couple of hours before bedtime works best for me.

Mar 17, 2015 (Started Jun 30, 2012)

  • Effectiveness
    Moderate (for insomnia)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: My understanding of melatonin is that taking more does not improve its effectiveness and may decrease its effectiveness.

  • 1 helpful mark

Dec 1, 2017 (Started Sep 12, 2008)

  • Effectiveness
    None (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take

  • 0 helpful marks
Last updated:
Showing 3 of 46 patient evaluations for Melatonin