What is Melatonin?

Category: Supplements

Most popular types: NatureMade Melatonin Circadin Natrol Melatonin Show all

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See also: Angelicalm Spray

Melatonin appears to be the primary sleep-regulating hormone of the body. It has been used by individuals suffering from insomnia, particularly when adjusting to shift-work cycles or jet lag. In the US Melatonin is available over-the-counter, however, it may require a prescription in some countries.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 600 249
Difficulty staying asleep 299 116
Periodic limb movement disorder 35 5
Unrefreshing or poor sleep 26 12
General health 24 8

Show all 89 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 15
Moderate 32
Mild 67
None 417

Commonly reported side effects and conditions associated with Melatonin

Side effect Patients Percentage
Drowsiness 14
Vivid dreams 7
Depressed mood 6
Grogginess in morning 5
Excessive daytime sleepiness (somnolence) 4
Fatigue 4

Show all 56 reported side effects

Dosages

Based on patients currently taking Melatonin

Dosage Patients Percentage
10 mg daily 26
3 mg daily 24
5 mg daily 19
3mg as needed 7
1 mg daily 6
6 mg daily 4
9 mg daily 2
5 mg twice daily 2
2 5mg as needed 2
5mg as needed 2

See all 23 dosages

Why patients stopped taking Melatonin

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 133
Other 85
Doctor's advice 44
Side effects too severe 31
Course of treatment ended 20
Personal research 18
Expense 15
See all 296 patients who've stopped taking Melatonin

Duration

Currently taking Melatonin

Duration Patients Percentage
1 - 6 months 3
6 months - 1 year 8
1 - 2 years 12
2 - 5 years 36
5 - 10 years 38
10 years or more 10

Stopped taking Melatonin

Duration Patients Percentage
Less than 1 month 48
1 - 6 months 80
6 months - 1 year 48
1 - 2 years 44
2 - 5 years 49
5 - 10 years 19
10 years or more 7
Adherence
Adherence Evaluations Percentage
Always 326
Usually 105
Sometimes 80
Never taken as prescribed 20
Burden
Burden Evaluations Percentage
Very hard to take 5
Somewhat hard to take 17
A little hard to take 62
Not at all hard to take 447
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 1
$25-49 18
< $25 223
Not specified 289

What people switch to and from

Patients started taking Melatonin after stopping:

Treatment Patients Percentage
Trazodone (Apo-Trazodone) 2
Clonazepam (Klonopin) 1
Hydroxyzine (Vistaril) 1
Lorazepam (Ativan) 1
Quetiapine (Seroquel) 1

Show all 6 treatments patients report switching from

Patients stopped taking Melatonin and switched to:

Treatment Patients Percentage
Bupropion (Wellbutrin) 1
Clonazepam (Klonopin) 1
Clonidine (Catapres) 1
Diazepam (Valium) 1
Doxepin (Sinequan) 1

Show all 8 treatments patients report switching to

Last updated:

46 patient evaluations for Melatonin

Jun 25, 2020 (Started Nov 15, 2011)

  • Effectiveness
    Major (for abnormal dreams)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: if i forget to take it, i almost always ave problems with acting out dreams. if i do take, it, i almost never act out my dreams
Cost: < $25 monthly

  • 0 helpful marks

Mar 1, 2020 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: I continue to take this medication b/c I feel it helps me sleep. However, I see no sign of abatement of nightmares or acting out my dreams in my sleep. I continue to clobber my husband, scream & kick him or just kick in the air.
Cost: < $25 monthly

Sep 20, 2017 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: After several nites of hideous nightmares and pummelling my husband in his sleep, I decided to increase the Melatonin to 5mg, 2 @hs. It has not made any difference so far.

Aug 18, 2017 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: My husband picked this up at the grocery store for me & he could only find it in gummy pills. I would prefer to take a pill but these gummy things do taste delicious. I take the melatonin to combat the REM Sleep Behavior D/O & it doesn't seem to lessen that problem (so far) but I think I am sleeping better. I will continue with the Melatonin in hopes it will help, and I haven't increased the dose as my doctor told me I can, so I can always try an added pill.

  • 0 helpful marks

Feb 24, 2020 (Started Jun 30, 2012)

  • Effectiveness
    Major (for insomnia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Taking one a couple of hours before bedtime works best for me.

Mar 17, 2015 (Started Jun 30, 2012)

  • Effectiveness
    Moderate (for insomnia)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: My understanding of melatonin is that taking more does not improve its effectiveness and may decrease its effectiveness.

  • 1 helpful mark
Last updated:
Showing 3 of 46 patient evaluations for Melatonin