What is Levothyroxine?

Category: Prescription Drugs

Most popular types: Synthroid Levoxyl Thyroxine Show all

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See also: Thyrolar-1

Levothyroxine is a synthetic form of the human hormone thyroxine. The drug is used to treat hypothyroidism (underactive thyroid), which can lead to weight gain, depression, and pain.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Hypothyroidism 3153 1061
Hashimoto's thyroiditis 540 209
General health 144 20
Thyroid cancer 108 30
Fatigue 36 19

Show all 88 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 43
Moderate 106
Mild 124
None 1085

Commonly reported side effects and conditions associated with Levothyroxine

Side effect Patients Percentage
Weight gain 33
Fatigue 32
Hair loss 28
Headaches 16
Heart palpitations 13
Nausea 12

Show all 163 reported side effects

Dosages

Based on patients currently taking Levothyroxine

Dosage Patients Percentage
0.1 mg daily 40
0.075 mg daily 35
0.05 mg daily 33
50 mcg (0.05 mg) daily 32
0.125 mg daily 27
0.025 mg daily 24
0.088 mg daily 22
100 mcg (0.1 mg) daily 19
0.15 mg daily 19
0.112 mg daily 16

See all 76 dosages

Why patients stopped taking Levothyroxine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 101
Doctor's advice 79
Other 68
Side effects too severe 54
Personal research 42
Change in health plan coverage 22
Course of treatment ended 18
Expense 13
See all 299 patients who've stopped taking Levothyroxine

Duration

Currently taking Levothyroxine

Duration Patients Percentage
1 - 6 months 4
6 months - 1 year 8
1 - 2 years 20
2 - 5 years 77
5 - 10 years 110
10 years or more 233

Stopped taking Levothyroxine

Duration Patients Percentage
Less than 1 month 29
1 - 6 months 55
6 months - 1 year 41
1 - 2 years 34
2 - 5 years 55
5 - 10 years 45
10 years or more 55
Adherence
Adherence Evaluations Percentage
Always 1169
Usually 152
Sometimes 9
Never taken as prescribed 28
Burden
Burden Evaluations Percentage
Very hard to take 26
Somewhat hard to take 90
A little hard to take 202
Not at all hard to take 1040
Cost per month
Cost per month Evaluations Percentage
$200+ 2
$100-199 2
$50-99 13
$25-49 63
< $25 809
Not specified 469

What people switch to and from

Patients started taking Levothyroxine after stopping:

Treatment Patients Percentage
Desiccated thyroid (Armour Thyroid) 24
Levothyroxine (Synthroid) 11
Liothyronine (T3) (Cytomel) 6
Methimazole (Tapazole) 2
Antidepressants 1

Show all 10 treatments patients report switching from

Patients stopped taking Levothyroxine and switched to:

Treatment Patients Percentage
Desiccated thyroid (Armour Thyroid) 60
Levothyroxine (Synthroid) 10
Liothyronine (T3) (Cytomel) 8
Amitriptyline (Elavil) 1
Duloxetine (Cymbalta) 1

Show all 12 treatments patients report switching to

Last updated:

95 patient evaluations for Levothyroxine

Apr 3, 2020 (Started Jun 15, 2016)

  • Effectiveness
    Moderate (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.025 mg Daily
Cost: < $25 monthly

Jan 6, 2019 (Started Jun 15, 2016)

  • Effectiveness
    Can't tell (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.025 mg Daily
Cost: < $25 monthly

Feb 21, 2018 (Started Jun 15, 2016)

  • Effectiveness
    Major (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.025 mg Daily

  • 0 helpful marks

Dec 8, 2019 (Started Jul 01, 1993)

  • Effectiveness
    Major (for Hashimoto's thyroiditis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mcg (0.1 mg) Daily
Cost: < $25 monthly

Jul 8, 2018 (Started Jul 01, 1993)

  • Effectiveness
    Major (for Hashimoto's thyroiditis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mcg (0.1 mg) Daily
Cost: < $25 monthly

  • 0 helpful marks

Nov 12, 2018 (Started Aug 06, 2007)

  • Effectiveness
    Slight (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mcg (0.15 mg) Daily

Aug 15, 2015 (Started Aug 06, 2007)

  • Effectiveness
    Can't tell (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mcg (0.15 mg) Daily

  • 0 helpful marks
Last updated:
Showing 3 of 95 patient evaluations for Levothyroxine