What is Letrozole?

Category: Prescription Drugs

Most popular types: Femara

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See also: Femara

Letrozole is an anticancer drug used as adjuvant treatment for postmenopausal hormone receptor positive early breast cancer. It may also be used for postmenopausal hormone receptor positive or hormone receptor unknown, locally-advanced, or metastatic breast cancer.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Breast cancer 33 20
Doctor recommendation 5 5
Female infertility 4 3
Endometriosis 1 0

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 3
Moderate 10
Mild 8
None 4

Commonly reported side effects and conditions associated with Letrozole

Side effect Patients Percentage
Joint pain 8
Hot flashes 4
Fatigue 2
Hair loss 2
Nausea 2
Bone pain 1

Show all 19 reported side effects

Dosages

Based on patients currently taking Letrozole

Dosage Patients Percentage
2.5 mg daily 6
5 mg daily 1
2 2.5mg as needed 1

Why patients stopped taking Letrozole

Multiple reasons could be selected

Reason Patients Percentage
Course of treatment ended 4
Did not seem to work 4
Side effects too severe 4
Doctor's advice 3
Other 1
See all 13 patients who've stopped taking Letrozole

Duration

Currently taking Letrozole

Duration Patients Percentage
1 - 6 months 2
1 - 2 years 4
2 - 5 years 1
10 years or more 1

Stopped taking Letrozole

Duration Patients Percentage
Less than 1 month 3
1 - 6 months 2
6 months - 1 year 1
1 - 2 years 3
2 - 5 years 3
5 - 10 years 1
Adherence
Adherence Evaluations Percentage
Always 24
Usually 1
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations Percentage
Very hard to take 0
Somewhat hard to take 3
A little hard to take 2
Not at all hard to take 20
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 0
$25-49 0
< $25 12
Not specified 13

What people switch to and from

Patients started taking Letrozole after stopping:

Treatment Patients Percentage
Anastrozole (Arimidex) 4
Tamoxifen (Nolvadex) 4
Clomiphene (Clomid) 1
Exemestane (Aromasin) 1
Leuprolide (Leuprorelin) (Lupron) 1

Patients stopped taking Letrozole and switched to:

Treatment Patients Percentage
Exemestane (Aromasin) 2
Anastrozole (Arimidex) 1
Everolimus (Afinitor) 1
Follitropin alpha 1
Levothyroxine (Synthroid) 1
Last updated:

1 patient evaluation for Letrozole

Jun 26, 2011 (Started Feb 05, 2009)

  • Effectiveness
    Major (for breast cancer)
  • Side effects
    Moderate (joint pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2.5 mg Daily
Side effects: joint pain

  • 0 helpful marks
Last updated:
Showing 1 of 1 patient evaluation for Letrozole