What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar disorder 9974 945
Epilepsy 3324 532
Bipolar II disorder 3200 491
Bipolar I disorder 1932 293
Borderline personality disorder 547 116
Depressed mood 197 120

Show all 230 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 283
Moderate 446
Mild 628
None 1032

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients Percentage
Weight gain 84
Dizziness 75
Headaches 72
Nausea 51
Rashes (redness, swelling) 50
Insomnia 49

Show all 416 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients Percentage
200 mg daily 40
100 mg daily 26
100 mg twice daily 15
400 mg daily 13
200 mg twice daily 12
150 mg twice daily 11
50 mg daily 10
150 mg daily 10
300 mg daily 8
25 mg daily 6

See all 39 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 490
Did not seem to work 443
Doctor's advice 289
Other 209
Expense 74
Personal research 61
Course of treatment ended 46
Change in health plan coverage 38
See all 1125 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients Percentage
1 - 6 months 2
6 months - 1 year 9
1 - 2 years 17
2 - 5 years 53
5 - 10 years 57
10 years or more 57

Stopped taking Lamotrigine

Duration Patients Percentage
Less than 1 month 247
1 - 6 months 246
6 months - 1 year 162
1 - 2 years 145
2 - 5 years 180
5 - 10 years 99
10 years or more 21
Adherence
Adherence Evaluations Percentage
Always 1963
Usually 299
Sometimes 50
Never taken as prescribed 77
Burden
Burden Evaluations Percentage
Very hard to take 104
Somewhat hard to take 218
A little hard to take 377
Not at all hard to take 1690
Cost per month
Cost per month Evaluations Percentage
$200+ 45
$100-199 50
$50-99 69
$25-49 124
< $25 1085
Not specified 1016

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients Percentage
Lithium Carbonate (Lithium Carbonate ER) 115
Divalproex sodium (Depakote) 65
Aripiprazole (Abilify) 56
Quetiapine (Seroquel) 51
Bupropion (Wellbutrin) 30

Show all 62 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients Percentage
Lithium Carbonate (Lithium Carbonate ER) 54
Aripiprazole (Abilify) 40
Quetiapine (Seroquel) 32
Divalproex sodium (Depakote) 26
Lurasidone (Latuda) 21

Show all 67 treatments patients report switching to

Last updated:

139 patient evaluations for Lamotrigine

Feb 23, 2020 (Started Jul 01, 2009)

  • Effectiveness
    Major (for bipolar II disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily

Jan 18, 2017 (Started Jul 01, 2009)

  • Effectiveness
    Major (for bipolar II disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Don't go off without talking to doctor. I came out of the fog after starting this medication.

  • 0 helpful marks

Dec 30, 2017 (Started Feb 15, 2015)

  • Effectiveness
    Major (for bipolar mixed episodes)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 20, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Can't tell (for epilepsy)
  • Effectiveness
    Slight (for seizures)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Twice daily
Advice & Tips: I could barely walk when my dose got up to 2 tablets twice a day.
Cost: $25-49 monthly

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for epilepsy)
  • Effectiveness
    Slight (for seizures)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 139 patient evaluations for Lamotrigine