What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar disorder 1605 931
Epilepsy 1114 526
Bipolar II disorder 808 486
Bipolar I disorder 468 293
Depressed mood 175 123
Major depressive disorder 164 132

Show all 216 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 280
Moderate 440
Mild 619
None 1014

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients Percentage
Weight gain 81
Dizziness 73
Headaches 71
Nausea 51
Rashes (redness, swelling) 50
Memory problems 49

Show all 415 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients Percentage
200 mg daily 71
100 mg daily 40
25 mg daily 26
400 mg daily 24
300 mg daily 23
200 mg twice daily 23
150 mg daily 22
100 mg twice daily 22
50 mg daily 17
150 mg twice daily 14

See all 47 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 474
Did not seem to work 415
Doctor's advice 277
Other 203
Expense 70
Personal research 57
Course of treatment ended 45
Change in health plan coverage 36
See all 1068 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 12
6 months - 1 year 10
1 - 2 years 35
2 - 5 years 98
5 - 10 years 116
10 years or more 91

Stopped taking Lamotrigine

Duration Patients Percentage
Less than 1 month 243
1 - 6 months 245
6 months - 1 year 160
1 - 2 years 145
2 - 5 years 179
5 - 10 years 96
10 years or more 20
Adherence
Adherence Evaluations Percentage
Always 1932
Usually 295
Sometimes 50
Never taken as prescribed 76
Burden
Burden Evaluations Percentage
Very hard to take 101
Somewhat hard to take 213
A little hard to take 374
Not at all hard to take 1665
Cost per month
Cost per month Evaluations Percentage
$200+ 43
$100-199 50
$50-99 67
$25-49 122
< $25 1078
Not specified 993

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients Percentage
Lithium Carbonate (Lithium Carbonate ER) 107
Divalproex sodium (Depakote) 57
Aripiprazole (Abilify) 49
Quetiapine (Seroquel) 45
Bupropion (Wellbutrin XL) 29

Show all 56 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients Percentage
Lithium Carbonate (Lithium Carbonate ER) 37
Aripiprazole (Abilify) 29
Quetiapine (Seroquel) 21
Divalproex sodium (Depakote) 17
Oxcarbazepine (Trileptal) 15

Show all 59 treatments patients report switching to

Last updated:

139 patient evaluations for Lamotrigine

Dec 30, 2017 (Started Feb 15, 2015)

  • Effectiveness
    Major (for bipolar mixed episodes)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 20, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Can't tell (for epilepsy)
  • Effectiveness
    Slight (for seizures)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Twice daily
Advice & Tips: I could barely walk when my dose got up to 2 tablets twice a day.
Cost: $25-49 monthly

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for epilepsy)
  • Effectiveness
    Slight (for seizures)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Major (for bipolar rapid cycling)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for depressed mood)
  • Effectiveness
    Major (for bipolar rapid cycling)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 139 patient evaluations for Lamotrigine