What is Lamivudine-Zidovudine (3TC/ZDV)?

Category: Prescription Drugs

Most popular types: Combivir Avocomb

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The combination of lamivudine (Epivir) and zidovudine (AZT, ZDP) is used to treat HIV in patients with or without acquired immunodeficiency syndrome (AIDS). Lamivudine and zidovudine are in a class of antiviral medications called synthetic nucleoside analogues.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Human immunodeficiency virus (HIV) 65 37
Support immune health 2 0
Depressed mood 1 0
Low CD4 count 1 2

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 1
Moderate 9
Mild 13
None 17

Commonly reported side effects and conditions associated with Lamivudine-Zidovudine (3TC/ZDV)

Side effect Patients Percentage
Diarrhea 7
Nausea 6
Fatigue 4
Lethargy 2
Tiredness 2
Anemia 1

Show all 11 reported side effects

Why patients stopped taking Lamivudine-Zidovudine (3TC/ZDV)

Multiple reasons could be selected

Reason Patients Percentage
Doctor's advice 17
Other 8
Side effects too severe 7
Personal research 5
Course of treatment ended 4
Did not seem to work 2
Change in health plan coverage 1
Expense 1
See all 37 patients who've stopped taking Lamivudine-Zidovudine (3TC/ZDV)

Duration

Stopped taking Lamivudine-Zidovudine (3TC/ZDV)

Duration Patients Percentage
Less than 1 month 3
1 - 6 months 4
6 months - 1 year 4
1 - 2 years 7
2 - 5 years 12
5 - 10 years 7
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 32
Usually 8
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations Percentage
Very hard to take 3
Somewhat hard to take 3
A little hard to take 9
Not at all hard to take 25
Cost per month
Cost per month Evaluations Percentage
$200+ 2
$100-199 2
$50-99 0
$25-49 3
< $25 20
Not specified 13

What people switch to and from

Patients started taking Lamivudine-Zidovudine (3TC/ZDV) after stopping:

Treatment Patients Percentage
Efavirenz-Emtricitabine-Tenofovir disoproxil fumarate (Atripla) 1

Patients stopped taking Lamivudine-Zidovudine (3TC/ZDV) and switched to:

Treatment Patients Percentage
Efavirenz-lamivudine-tenofovir disoproxil (EFV/3TC/TDF) 1
Emtricitabine-Tenofovir Alafenamide (Descovy) 1
Triumeq 1
Last updated:

5 patient evaluations for Lamivudine-Zidovudine (3TC/ZDV)

Mar 16, 2015 (Started Mar 10, 2012)

  • Effectiveness
    Major (for human immunodeficiency virus (HIV))
  • Side effects
    Moderate (diarrhea, stomach irritation if not enough food in stomach, anxious mood)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg-300 mg Daily
Advice & Tips: help to control acné but not recovery the anemia, low hematocrit and low with cells

  • 0 helpful marks

Jun 15, 2013 (Started Jun 06, 2008)

  • Effectiveness
    Major (for human immunodeficiency virus (HIV))
  • Side effects
    Mild (fatigue, nausea, diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 150 mg-300 mg Daily
Cost: < $25 monthly
Side effects: fatigue, nausea, diarrhea

Jan 14, 2013 (Started Jun 06, 2008)

  • Effectiveness
    Major (for human immunodeficiency virus (HIV))
  • Side effects
    Mild (fatigue, nausea, diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 150 mg-300 mg Daily
Cost: < $25 monthly
Side effects: fatigue, nausea, diarrhea

Aug 29, 2011 (Started Jun 06, 2008)

  • Effectiveness
    Major (for human immunodeficiency virus (HIV))
  • Side effects
    Mild (fatigue, nausea, diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 150 mg-300 mg Daily
Cost: < $25 monthly
Side effects: fatigue, nausea, diarrhea

Oct 20, 2010 (Started Jun 06, 2008)

  • Effectiveness
    Major (for human immunodeficiency virus (HIV))
  • Side effects
    Moderate (fatigue, nausea, diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 150 mg-300 mg Daily
Cost: < $25 monthly
Side effects: fatigue, nausea, diarrhea

Feb 11, 2009 (Started Jun 06, 2008)

  • Effectiveness
    Major (for human immunodeficiency virus (HIV))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 2 x 150 mg-300 mg Daily
Cost: < $25 monthly
Side effects: fatigue, nausea, diarrhea

Aug 24, 2008 (Started Jun 06, 2008)

  • Effectiveness
    Major (for human immunodeficiency virus (HIV))
  • Side effects
    Moderate (fatigue, nausea, diarrhea)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 2 x 150 mg-300 mg Daily
Cost: < $25 monthly
Side effects: fatigue, nausea, diarrhea

  • 0 helpful marks

Apr 20, 2010 (Started Apr 29, 2006)

  • Effectiveness
    Major (for human immunodeficiency virus (HIV))
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 2 x 150 mg-300 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Lamivudine-Zidovudine (3TC/ZDV)