What is Interferon beta-1a SubQ injection?

Category: Prescription Drugs

Most popular types: Rebif Rebif Rebidose

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Interferon beta-1a is an immunomodulator used to prevent episodes of symptoms and slow the development of disability in patients with relapsing-remitting multiple sclerosis. It comes as a solution to inject subcutaneously (under the skin) three times a week, ideally the same 3 days each week.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 10724 1391
Stiffness/spasticity 39 27
Fatigue 28 5
General health 18 12
Improve mobility 9 4
Hepatitis C 5 1

Show all 38 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 275
Moderate 440
Mild 501
None 200

Commonly reported side effects and conditions associated with Interferon beta-1a SubQ injection

Side effect Patients Percentage
Injection site redness 181
Headaches 164
Muscle aches 161
Fever/chills 138
Injection site pain 110
Fatigue 69

Show all 236 reported side effects

Dosages

Based on patients currently taking Interferon beta-1a SubQ injection

Dosage Patients Percentage
44 mcg/0.5 mL 3 times a week 8
44 mcg 3 times a week 6
30 mcg 3 times a week 2
8 other 3 times a week 1
8.8 mcg m,w,f 1
22 mcg 3 times a week 1
88 mcg weekly 1
44 mcg/0.5 mL m,w,f 1
3 x 44 mcg/0.5 mL weekly 1
132 mcg 3 times a week 1

See all 13 dosages

Why patients stopped taking Interferon beta-1a SubQ injection

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 767
Did not seem to work 536
Doctor's advice 465
Other 313
Expense 83
Personal research 71
Course of treatment ended 33
Change in health plan coverage 31
See all 1606 patients who've stopped taking Interferon beta-1a SubQ injection

Duration

Currently taking Interferon beta-1a SubQ injection

Duration Patients Percentage
6 months - 1 year 1
1 - 2 years 2
2 - 5 years 6
5 - 10 years 9
10 years or more 12

Stopped taking Interferon beta-1a SubQ injection

Duration Patients Percentage
Less than 1 month 93
1 - 6 months 312
6 months - 1 year 264
1 - 2 years 304
2 - 5 years 393
5 - 10 years 160
10 years or more 37
Adherence
Adherence Evaluations Percentage
Always 1112
Usually 215
Sometimes 33
Never taken as prescribed 56
Burden
Burden Evaluations Percentage
Very hard to take 168
Somewhat hard to take 393
A little hard to take 439
Not at all hard to take 416
Cost per month
Cost per month Evaluations Percentage
$200+ 85
$100-199 50
$50-99 198
$25-49 247
< $25 433
Not specified 403

What people switch to and from

Patients started taking Interferon beta-1a SubQ injection after stopping:

Treatment Patients Percentage
Glatiramer acetate (Copaxone) 40
Interferon beta-1a IM Injection (Avonex) 27
Interferon beta-1b SubQ Injection (Betaseron) 12
Dimethyl fumarate (Tecfidera) 9
Natalizumab (Tysabri) 5

Show all 14 treatments patients report switching from

Patients stopped taking Interferon beta-1a SubQ injection and switched to:

Treatment Patients Percentage
Dimethyl fumarate (Tecfidera) 69
Glatiramer acetate (Copaxone) 61
Natalizumab (Tysabri) 54
Fingolimod (Gilenya) 48
Teriflunomide (Aubagio) 21

Show all 21 treatments patients report switching to

Last updated:

132 patient evaluations for Interferon beta-1a SubQ injection

Oct 1, 2017 (Started Oct 01, 2007)

  • Effectiveness
    None (for multiple sclerosis)
  • Side effects
    Mild (extreme flu like malaise)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Advice & Tips: I took the medicine for almost 10 years religiously from 2007-2017 roughly. I took shots 3 days a week before going to bed. 50% of the time, I had mild flue like symptoms at night. Over the course of the 10 years I slowly lost mobility on my left side, I never had an exacerbation, prompting my neurologist to put me on ocrevus which is for PPMS.
Cost: $25-49 monthly

  • 0 helpful marks

Aug 31, 2016 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: $50-99 monthly

Jul 29, 2011 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: $25-49 monthly

Jun 15, 2010 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Advice & Tips: I do my shots Sun, Tues, Thurs. After the first 6 months or so I had no more reactions at all. I can do the shot and then do whatever I had planned. I find that doing the shot freehand is much easier after the initial shock of actually sticking the needle in goes by. Now it is just something I do.
Cost: < $25 monthly

May 21, 2010 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: < $25 monthly

Oct 29, 2009 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: < $25 monthly

Sep 23, 2009 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: < $25 monthly

  • 0 helpful marks

Apr 20, 2016 (Started May 07, 2004)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Cost: < $25 monthly
Side effects: fatigue, fatigue

Jul 10, 2015 (Started May 07, 2004)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Moderate (fatigue)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Advice & Tips: I am taking therapy in till noon, or according my work load Still working, traveling, walking minor impact, don't think about illness constantly
Cost: < $25 monthly
Side effects: fatigue, fatigue

Aug 7, 2010 (Started May 07, 2004)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Advice & Tips: because of side effects i take injection 12-20h before major workload
Side effects: fatigue, fatigue

  • 0 helpful marks
Last updated:
Showing 3 of 132 patient evaluations for Interferon beta-1a SubQ injection