What is Glycopyrrolate?

Category: Prescription Drugs

Most popular types: Robinul Glycopyrronium Robinul Forte

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Glycopyrrolate is an anticholinergic drug which slows the activity of the salivary glands, stomach and intestinal tract, thus relieving cramping and reducing acid secretion. It is commonlu used in the treatment of peptic ulcers, but also has a specific use in ALS/MND of reducing excess saliva.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Excess saliva 103 47
Amyotrophic lateral sclerosis 15 12
Excessive sweating 6 3
Hyperhidrosis disorder 5 5
Excess mucus 4 3
Drooling 3 0

Show all 24 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 7
Moderate 5
Mild 9
None 44

Commonly reported side effects and conditions associated with Glycopyrrolate

Side effect Patients Percentage
Dry mouth 6
Constipation 3
Dry eyes 3
Bladder problems 1
Diarrhea 1
Dry mouth at night 1

Show all 12 reported side effects

Dosages

Based on patients currently taking Glycopyrrolate

Dosage Patients Percentage
1 mg twice daily 2
0.8 mg daily 1
2 mg daily 1
2 mg three times daily 1
2.25 mg three times daily 1

Why patients stopped taking Glycopyrrolate

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 20
Side effects too severe 9
Other 4
Doctor's advice 3
Change in health plan coverage 1
Course of treatment ended 1
Expense 1
Personal research 1
See all 35 patients who've stopped taking Glycopyrrolate

Duration

Currently taking Glycopyrrolate

Duration Patients Percentage
2 - 5 years 3
5 - 10 years 2
10 years or more 1

Stopped taking Glycopyrrolate

Duration Patients Percentage
Less than 1 month 12
1 - 6 months 9
6 months - 1 year 7
1 - 2 years 3
2 - 5 years 3
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 49
Usually 8
Sometimes 3
Never taken as prescribed 5
Burden
Burden Evaluations Percentage
Very hard to take 3
Somewhat hard to take 2
A little hard to take 10
Not at all hard to take 50
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 0
$50-99 3
$25-49 5
< $25 25
Not specified 31

What people switch to and from

Patients started taking Glycopyrrolate after stopping:

Treatment Patients Percentage
Amitriptyline (Elavil) 1
Dextromethorphan-Quinidine (Nuedexta) 1
Dicyclomine (Bentyl) 1

Patients stopped taking Glycopyrrolate and switched to:

Treatment Patients Percentage
Amitriptyline (Elavil) 2
Amino acid complex (Calm Supplement) 1
Atropine ophthalmic 1
Botulinum Toxin Type A (Botox) 1
Ropinirole (Requip) 1

Show all 6 treatments patients report switching to

Last updated:

11 patient evaluations for Glycopyrrolate

May 12, 2015 (Started Apr 14, 2015)

  • Effectiveness
    Slight (for excess saliva)
  • Side effects
    Severe (constipation)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 1 mg Twice daily
Advice & Tips: The slight benefit in decreased saliva wasn't worth the severe constipation.

Mar 7, 2015 (Started Apr 14, 2015)

  • Effectiveness
    Slight (for excess saliva)
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Not at all hard to take

  • 0 helpful marks

Apr 27, 2014 (Started Feb 20, 2012)

  • Effectiveness
    Moderate (for gastroesophageal reflux disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 mg Daily
Cost: < $25 monthly

Mar 22, 2012 (Started Feb 20, 2012)

  • Effectiveness
    Moderate (for gastroesophageal reflux disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 mg Daily
Advice & Tips: My doctor suggested taking Glycopyrrolate with the Omeprazole, since alone the first one provides insufficient relief. Seems their actions compliment each other's, which provides additional acid reflux relief. Now after a month of taking both, most days I have very good results and have been able to eliminate relying on Alka Seltzer or baking soda.
Cost: < $25 monthly

  • 0 helpful marks

Jan 1, 2012 (Started Jan 03, 2007)

  • Effectiveness
    Moderate (for amyotrophic lateral sclerosis)
  • Effectiveness
    Slight (for choking on food)
  • Effectiveness
    Major (for excess saliva)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.8 mg Daily
Cost: < $25 monthly
Side effects: dry mouth

Oct 28, 2009 (Started Jan 03, 2007)

  • Effectiveness
    Moderate (for choking on food)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.8 mg Daily
Cost: < $25 monthly
Side effects: dry mouth

Apr 4, 2009 (Started Jan 03, 2007)

  • Effectiveness
    Moderate (for choking on food)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.8 mg Daily
Cost: < $25 monthly
Side effects: dry mouth

Jan 27, 2009 (Started Jan 03, 2007)

  • Effectiveness
    Moderate (for choking on food)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.8 mg Daily
Cost: < $25 monthly
Side effects: dry mouth

Aug 23, 2008 (Started Jan 03, 2007)

  • Effectiveness
    Major (for choking on food)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.8 mg Daily
Cost: < $25 monthly
Side effects: dry mouth

  • 0 helpful marks
Last updated:
Showing 3 of 11 patient evaluations for Glycopyrrolate