What is Fluoxetine?

Category: Prescription Drugs

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Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It is used to treat major depressive disorder, moderate to severe bulimia nervosa, obsessive compulsive and panic disorders. It may also be used for selective mutism and dementia related agitation.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 14446 899
Depressed mood 5863 865
Post-traumatic stress disorder 5105 234
Persistent depressive disorder (dysthymia) 1017 165
Mild depression 770 119
Borderline personality disorder 719 71

Show all 206 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 214
Moderate 370
Mild 520
None 886

Commonly reported side effects and conditions associated with Fluoxetine

Side effect Patients Percentage
Decreased sex drive (libido) 76
Sexual dysfunction 73
Nausea 70
Weight gain 68
Anxious mood 44
Fatigue 37

Show all 298 reported side effects

Dosages

Based on patients currently taking Fluoxetine

Dosage Patients Percentage
20 mg daily 49
40 mg daily 37
10 mg daily 14
60 mg daily 12
80 mg daily 9
30 mg daily 4
20 mg three times daily 2
1 tablet(s) daily 1
1.5 mL daily 1
15 mg daily 1

See all 15 dosages

Why patients stopped taking Fluoxetine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 903
Side effects too severe 508
Doctor's advice 485
Other 312
Personal research 104
Course of treatment ended 96
Expense 45
Change in health plan coverage 42
See all 1827 patients who've stopped taking Fluoxetine

Duration

Currently taking Fluoxetine

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 7
6 months - 1 year 4
1 - 2 years 12
2 - 5 years 42
5 - 10 years 27
10 years or more 47

Stopped taking Fluoxetine

Duration Patients Percentage
Less than 1 month 293
1 - 6 months 311
6 months - 1 year 274
1 - 2 years 272
2 - 5 years 300
5 - 10 years 158
10 years or more 144
Adherence
Adherence Evaluations Percentage
Always 1500
Usually 337
Sometimes 70
Never taken as prescribed 83
Burden
Burden Evaluations Percentage
Very hard to take 66
Somewhat hard to take 138
A little hard to take 312
Not at all hard to take 1474
Cost per month
Cost per month Evaluations Percentage
$200+ 4
$100-199 5
$50-99 23
$25-49 76
< $25 1043
Not specified 839

What people switch to and from

Patients started taking Fluoxetine after stopping:

Treatment Patients Percentage
Sertraline (Zoloft) 93
Venlafaxine (Effexor XR) 71
Citalopram (Celexa) 66
Duloxetine (Cymbalta) 53
Bupropion (Wellbutrin) 46

Show all 51 treatments patients report switching from

Patients stopped taking Fluoxetine and switched to:

Treatment Patients Percentage
Duloxetine (Cymbalta) 161
Venlafaxine (Effexor XR) 152
Sertraline (Zoloft) 140
Bupropion (Wellbutrin) 107
Escitalopram (Lexapro) 75

Show all 64 treatments patients report switching to

Last updated:

138 patient evaluations for Fluoxetine

Jun 25, 2020 (Started Jul 01, 2018)

  • Effectiveness
    Slight (for obsessive-compulsive disorder)
  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    None (for complex post-traumatic stress disorder)
  • Side effects
    Mild (blurry vision)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: Still taking this. Only side effect so far is blurry vision at night. Still of very little help, but better than nothing

May 27, 2019 (Started Jul 01, 2018)

  • Effectiveness
    Slight (for obsessive-compulsive disorder)
  • Effectiveness
    None (for complex post-traumatic stress disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: It has very little effectiveness against intrusive thoughts but no side effects at all so I keep taking it. I think I could have a higher dose without any problems but they say 60mg is the maximum

  • 0 helpful marks

Apr 27, 2020 (Started Mar 18, 2002)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Effectiveness
    Major (for mood swings)
  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 40 mg Daily
Cost: < $25 monthly

Feb 24, 2020 (Started Mar 18, 2002)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Effectiveness
    Moderate (for mood swings)
  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 40 mg Daily
Cost: < $25 monthly

Jan 17, 2018 (Started Mar 18, 2002)

  • Effectiveness
    Moderate (for fatigue)
  • Effectiveness
    Moderate (for mood swings)
  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 40 mg Daily
Cost: < $25 monthly

Mar 7, 2016 (Started Mar 18, 2002)

  • Effectiveness
    Major (for fatigue)
  • Effectiveness
    Moderate (for mood swings)
  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 40 mg Daily
Advice & Tips: I'm taking 40mg of Fluoxetine daily and not taking Provigil, seems to be helping with fatigue.
Cost: < $25 monthly

Jul 26, 2012 (Started Mar 18, 2002)

  • Effectiveness
    Moderate (for fatigue)
  • Effectiveness
    Slight (for mood swings)
  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I think I need a bigger dose.
Cost: < $25 monthly

Oct 8, 2010 (Started Mar 18, 2002)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Effectiveness
    Major (for fatigue)
  • Effectiveness
    Major (for mood swings)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I always take 20mg of this right after 200mg of Provigil. The purpose is to counter the fiesty mood Provigil puts me in.
Cost: < $25 monthly

  • 0 helpful marks

Jan 9, 2019 (Started Feb 01, 2018)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Moderate (diarrhea, decreased sex drive (libido), vivid dreams)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

Apr 7, 2018 (Started Feb 01, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (diarrhea, decreased sex drive (libido), vivid dreams)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 138 patient evaluations for Fluoxetine