What is Estradiol topical?

Category: Prescription Drugs

Most popular types: Estrace Vaginal Cream Vagifem Estring Show all

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See also: Wiley protocol HRT

Estradiol topical is a vaginal cream preparation used for the treatment of vulvar and vaginal atrophy; postmenopausal symptoms of urinary urgency and painful urination.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Vaginal dryness 17 7
Bladder problems 11 12
Support hormone balance 6 2
Vaginal atrophy 3 9
Vaginal pain 3 1

Show all 33 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 1
Moderate 2
Mild 1
None 30

Commonly reported side effects and conditions associated with Estradiol topical

Side effect Patients Percentage
Atopic dermatitis 1
Dry eyes 1
Pain in left eye 1
Rashes (redness, swelling) 1
Urinary urgency 1

Dosages

Based on patients currently taking Estradiol topical

Dosage Patients Percentage
0.1 mg weekly 2
10 mcg weekly 2
0.02 % weekly 1
0.01 % every other day 1
2 mg monthly 1
0.25 % twice daily 1
25other as needed 1

Why patients stopped taking Estradiol topical

Multiple reasons could be selected

Reason Patients Percentage
Other 5
Doctor's advice 4
Side effects too severe 3
Course of treatment ended 2
Did not seem to work 1
Expense 1
Personal research 1
See all 13 patients who've stopped taking Estradiol topical

Duration

Currently taking Estradiol topical

Duration Patients Percentage
2 - 5 years 3
5 - 10 years 2
10 years or more 4

Stopped taking Estradiol topical

Duration Patients Percentage
Less than 1 month 3
1 - 6 months 4
6 months - 1 year 2
1 - 2 years 2
2 - 5 years 2
Adherence
Adherence Evaluations Percentage
Always 24
Usually 7
Sometimes 3
Never taken as prescribed 0
Burden
Burden Evaluations Percentage
Very hard to take 11
Somewhat hard to take 3
A little hard to take 9
Not at all hard to take 11
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 8
$50-99 2
$25-49 3
< $25 4
Not specified 16

What people switch to and from

Patients started taking Estradiol topical after stopping:

Treatment Patients Percentage
Estradiol Patch (Estrogen patch) 2
Estradiol (Estrace) 1
Estrogen derivative (Premarin) 1
Levofloxacin (Levaquin) 1

Patients stopped taking Estradiol topical and switched to:

Treatment Patients Percentage
Estradiol (Estrace) 1
Pregabalin (Lyrica) 1
Last updated:

5 patient evaluations for Estradiol topical

Feb 16, 2011 (Started Sep 07, 2007)

  • Effectiveness
    Major (for bladder problems)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.1 mg Daily

  • 0 helpful marks

Nov 15, 2010 (Started Jun 01, 2010)

  • Effectiveness
    Slight (for raise estrogen levels)
  • Side effects
    Moderate (dry eyes)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25 mcg Weekly
Advice & Tips: More urination, still dry and irritation....
Side effects: dry eyes

  • 0 helpful marks

Jun 25, 2010 (Started Jan 19, 2008)

  • Effectiveness
    Major (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mcg Weekly
Advice & Tips: According to my Urologist, I look good, and it seems to be doing it's job just fine!

Jan 19, 2009 (Started Jan 19, 2008)

  • Effectiveness
    Major (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mcg Weekly
Advice & Tips: Definitely use this instead of the cream version!

  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Estradiol topical