What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

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Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 582 274
Bipolar disorder 412 249
Migraine headaches 109 58
Bipolar II disorder 68 48
Bipolar I disorder 53 36
Bipolar manic episodes 45 34

Show all 110 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 191
Moderate 207
Mild 194
None 191

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients Percentage
Weight gain 153
Hair loss 49
Fatigue 41
Drowsiness 26
Tremor in hands 25
Nausea 19

Show all 216 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients Percentage
1000 mg daily 12
500 mg daily 11
500 mg twice daily 11
250 mg daily 4
750 mg daily 4
1500 mg daily 4
2000 mg daily 4
250 mg twice daily 3
125 mg daily 2
1000 mg twice daily 2

See all 17 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 351
Did not seem to work 256
Doctor's advice 179
Other 110
Personal research 35
Expense 31
Course of treatment ended 27
Change in health plan coverage 12
See all 660 patients who've stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 4
6 months - 1 year 2
1 - 2 years 6
2 - 5 years 14
5 - 10 years 20
10 years or more 18

Stopped taking Divalproex sodium

Duration Patients Percentage
Less than 1 month 126
1 - 6 months 143
6 months - 1 year 77
1 - 2 years 82
2 - 5 years 134
5 - 10 years 50
10 years or more 59
Adherence
Adherence Evaluations Percentage
Always 614
Usually 116
Sometimes 25
Never taken as prescribed 28
Burden
Burden Evaluations Percentage
Very hard to take 59
Somewhat hard to take 124
A little hard to take 119
Not at all hard to take 481
Cost per month
Cost per month Evaluations Percentage
$200+ 19
$100-199 19
$50-99 34
$25-49 63
< $25 309
Not specified 339

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients Percentage
Lithium Carbonate (Lithium Carbonate ER) 42
Lamotrigine (Lamictal) 22
Topiramate (Topamax) 14
Aripiprazole (Abilify) 12
Carbamazepine (Tegretol) 6

Show all 47 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients Percentage
Lamotrigine (Lamictal) 39
Carbamazepine (Tegretol) 12
Levetiracetam (Keppra) 12
Lithium Carbonate (Lithium Carbonate ER) 12
Oxcarbazepine (Trileptal) 9

Show all 38 treatments patients report switching to

Last updated:

65 patient evaluations for Divalproex sodium

Sep 19, 2017 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for bipolar disorder)
  • Side effects
    Moderate (head pressure)
  • Adherence
    Sometimes
  • Burden
    Somewhat hard to take
Dosage: 500 mg Daily
Cost: < $25 monthly

Apr 9, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for bipolar disorder)
  • Side effects
    Mild (head pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 250 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 250 mg Daily

  • 0 helpful marks

Sep 23, 2016 (Started Feb 28, 2015)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 65 patient evaluations for Divalproex sodium