What is Dimethyl fumarate?

Category: Prescription Drugs

Most popular types: Tecfidera

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Dimethyl fumarate is primarily used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 1053 920
Participate in clinical trial 11 13
Psoriasis 2 4
Arthritis pain 1 0
Brain atrophy cerebrum 1 0

Show all 15 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 147
Moderate 171
Mild 374
None 240

Commonly reported side effects and conditions associated with Dimethyl fumarate

Side effect Patients Percentage
Flushing 201
Facial flushing 65
Diarrhea 58
Nausea 55
Stomach pain 46
Itching 30

Show all 214 reported side effects

Dosages

Based on patients currently taking Dimethyl fumarate

Dosage Patients Percentage
240 mg twice daily 26
480 mg daily 11
120 mg twice daily 8
240 mg daily 6
480 mg twice daily 6
2 capsule(s) twice daily 3
120 mg daily 3
57600 mg twice daily 2
1 capsule(s) twice daily 1
1 mg twice daily 1

See all 23 dosages

Why patients stopped taking Dimethyl fumarate

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 173
Doctor's advice 107
Did not seem to work 84
Other 48
Course of treatment ended 13
Personal research 10
Change in health plan coverage 7
Expense 7
See all 334 patients who've stopped taking Dimethyl fumarate

Duration

Currently taking Dimethyl fumarate

Duration Patients Percentage
1 - 6 months 4
6 months - 1 year 1
1 - 2 years 3
2 - 5 years 25
5 - 10 years 45
10 years or more 3

Stopped taking Dimethyl fumarate

Duration Patients Percentage
Less than 1 month 66
1 - 6 months 74
6 months - 1 year 58
1 - 2 years 66
2 - 5 years 69
5 - 10 years 4
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 736
Usually 129
Sometimes 17
Never taken as prescribed 50
Burden
Burden Evaluations Percentage
Very hard to take 46
Somewhat hard to take 62
A little hard to take 135
Not at all hard to take 689
Cost per month
Cost per month Evaluations Percentage
$200+ 29
$100-199 7
$50-99 30
$25-49 51
< $25 471
Not specified 344

What people switch to and from

Patients started taking Dimethyl fumarate after stopping:

Treatment Patients Percentage
Glatiramer acetate (Copaxone) 131
Interferon beta-1a IM Injection (Avonex) 61
Interferon beta-1a SubQ injection (Rebif) 57
Natalizumab (Tysabri) 48
Fingolimod (Gilenya) 30

Show all 20 treatments patients report switching from

Patients stopped taking Dimethyl fumarate and switched to:

Treatment Patients Percentage
Teriflunomide (Aubagio) 47
Glatiramer acetate (Copaxone) 42
Natalizumab (Tysabri) 36
Fingolimod (Gilenya) 27
Ocrelizumab (Ocrevus) 26

Show all 19 treatments patients report switching to

Last updated:

37 patient evaluations for Dimethyl fumarate

Feb 9, 2019 (Started Sep 04, 2017)

  • Effectiveness
    Slight (for multiple sclerosis)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take

  • 0 helpful marks

Jan 26, 2019 (Started Jun 14, 2013)

  • Effectiveness
    Major (for psoriasis)
  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: Still working daily. No Psoriasis!
Cost: < $25 monthly

Jun 21, 2014 (Started Jun 14, 2013)

  • Effectiveness
    Major (for psoriasis)
  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: After 1st year, Psoriasis is still clear. Still happy I made the swtch from Rebif to Tecfedera. Occasionally I have flushing, but it is more amusing than it is bothersome.
Cost: < $25 monthly

Jul 31, 2013 (Started Jun 14, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: No longer heat intolerant Increased energy level Able to focus on task for longer period of time Less cog fog, clearer thinking More interest in hobbies Improved Psoriasis (no current skin lesions) Improved hemorrhoids
Cost: < $25 monthly

  • 4 helpful marks

Dec 15, 2017 (Started May 16, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Severe (increased indexes for PML.)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Advice & Tips: when I had been taking Tecfidera, I had taken a low-dose aspirin a few minutes before swallowing the capsule. The low-dose aspirin relieved the flushing feeling on my face and neck.
Cost: < $25 monthly

Sep 15, 2017 (Started May 16, 2013)

  • Effectiveness
    None (for multiple sclerosis)
  • Side effects
    Severe (increased indexes for PML.)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 37 patient evaluations for Dimethyl fumarate