What is Desvenlafaxine?

Category: Prescription Drugs

Most popular types: Pristiq Exsira

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Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is an extended release formulation believed to treat depression by affecting the levels of serotonin and norepinephrine, two neurotransmitters associated with depression.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 263 185
Major depressive disorder 234 157
Anxious mood 115 89
Fibromyalgia 40 34
Bipolar disorder 24 12
Pain 11 9

Show all 52 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 57
Moderate 70
Mild 95
None 171

Commonly reported side effects and conditions associated with Desvenlafaxine

Side effect Patients Percentage
Decreased sex drive (libido) 16
Weight gain 13
Nausea 11
Dizziness 9
Dry mouth 9
Sedation 8

Show all 103 reported side effects

Dosages

Based on patients currently taking Desvenlafaxine

Dosage Patients Percentage
50 mg daily 22
100 mg daily 21
25 mg daily 5
150 mg daily 3
200 mg daily 2
50 mg twice daily 1
150 mg twice daily 1

Why patients stopped taking Desvenlafaxine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 92
Side effects too severe 62
Doctor's advice 45
Expense 42
Other 32
Change in health plan coverage 11
Course of treatment ended 7
Personal research 7
See all 212 patients who've stopped taking Desvenlafaxine

Duration

Currently taking Desvenlafaxine

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 4
6 months - 1 year 3
1 - 2 years 5
2 - 5 years 16
5 - 10 years 16
10 years or more 10

Stopped taking Desvenlafaxine

Duration Patients Percentage
Less than 1 month 31
1 - 6 months 65
6 months - 1 year 43
1 - 2 years 39
2 - 5 years 29
5 - 10 years 7
Adherence
Adherence Evaluations Percentage
Always 337
Usually 37
Sometimes 3
Never taken as prescribed 16
Burden
Burden Evaluations Percentage
Very hard to take 14
Somewhat hard to take 27
A little hard to take 47
Not at all hard to take 305
Cost per month
Cost per month Evaluations Percentage
$200+ 7
$100-199 15
$50-99 39
$25-49 71
< $25 116
Not specified 145

What people switch to and from

Patients started taking Desvenlafaxine after stopping:

Treatment Patients Percentage
Venlafaxine (Effexor XR) 30
Duloxetine (Cymbalta) 17
Fluoxetine (Prozac) 14
Escitalopram (Lexapro) 13
Bupropion (Wellbutrin XL) 11

Show all 28 treatments patients report switching from

Patients stopped taking Desvenlafaxine and switched to:

Treatment Patients Percentage
Venlafaxine (Effexor XR) 10
Duloxetine (Cymbalta) 6
Fluoxetine (Prozac) 5
Vilazodone (Viibryd) 4
Vortioxetine (Trintellix) 4

Show all 22 treatments patients report switching to

Last updated:

27 patient evaluations for Desvenlafaxine

Jun 8, 2018 (Started Dec 19, 2017)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Advice & Tips: Now taking 200mg pill. It is the target dosage. It seems to be working fine.
Cost: $25-49 monthly

Jan 23, 2018 (Started Dec 19, 2017)

  • Effectiveness
    Can't tell (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Advice & Tips: Takes a while to work. hoping for the best.
Cost: $25-49 monthly

Dec 27, 2017 (Started Dec 19, 2017)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 25 mg Daily
Advice & Tips: It takes awhile to start to work. My Dr. set me up on 25mg but I feel I should be on a stronger dosage. Will take that up with her at my next appointment.
Cost: $25-49 monthly

  • 0 helpful marks

Mar 22, 2017 (Started Jun 19, 2008)

  • Effectiveness
    Major (for nerve pain (neuralgia))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Advice & Tips: 50 mg is for everyone but can go to 100 but usually no difference at all.. I was on effexor and then cynbalta both which didn't work out for me and then this one did.. all 3 are serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. ... It increases serotonin and norepinephrine activity in the brain, which regulates mood.
Cost: < $25 monthly

  • 0 helpful marks

Jul 25, 2015 (Started Mar 15, 2014)

  • Effectiveness
    Can't tell (for major depressive disorder)
  • Side effects
    Moderate (agoraphobia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Advice & Tips: I DID NOT REALLY REALIZE THE ANXIETY AND AGORAPHOBIA WAS BECAUSE OF THE PRISTIQ UNTIL RECENTLY.

  • 0 helpful marks
Last updated:
Showing 3 of 27 patient evaluations for Desvenlafaxine