What is Desipramine?

Category: Prescription Drugs

Most popular types: Norpramin Pertofrane

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Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. It is sold under the brand names Norpramin® and Pertofrane®. It is used to treat depression, neuropathic pain, and ADHD.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Nerve pain (neuralgia) 16 14
Depressed mood 11 8
Major depressive disorder 10 10
Pain 5 1
Complex regional pain syndrome type I 3 0

Show all 26 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 4
Moderate 10
Mild 8
None 20

Commonly reported side effects and conditions associated with Desipramine

Side effect Patients Percentage
Dry mouth 2
Dry mouth at night 2
Nausea 2
Bad breath (halitosis) 1
Bad taste in mouth 1
Blurry vision 1

Show all 29 reported side effects

Dosages

Based on patients currently taking Desipramine

Dosage Patients Percentage
25 mg daily 1
200 mg daily 1

Why patients stopped taking Desipramine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 15
Doctor's advice 13
Side effects too severe 11
Course of treatment ended 5
Other 3
Personal research 1
See all 34 patients who've stopped taking Desipramine

Duration

Currently taking Desipramine

Duration Patients Percentage
1 - 2 years 1
5 - 10 years 1

Stopped taking Desipramine

Duration Patients Percentage
Less than 1 month 3
1 - 6 months 13
6 months - 1 year 4
1 - 2 years 8
2 - 5 years 3
5 - 10 years 2
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 34
Usually 7
Sometimes 1
Never taken as prescribed 0
Burden
Burden Evaluations Percentage
Very hard to take 0
Somewhat hard to take 2
A little hard to take 6
Not at all hard to take 34
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 1
$50-99 4
$25-49 0
< $25 18
Not specified 19

What people switch to and from

Patients started taking Desipramine after stopping:

Treatment Patients Percentage
Bupropion (Wellbutrin XL) 2
Venlafaxine (Effexor XR) 2
Fluoxetine (Prozac) 1
Imipramine (Tofranil) 1
Mirtazapine (Remeron) 1

Show all 7 treatments patients report switching from

Patients stopped taking Desipramine and switched to:

Treatment Patients Percentage
Fluoxetine (Prozac) 3
Imipramine (Tofranil) 1
Paroxetine (Paxil) 1
Selegiline (Zelapar) 1
Last updated:

3 patient evaluations for Desipramine

Jul 7, 2010 (Started Jan 01, 1992)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Advice & Tips: I have a "pill minder" box" that I picked up at Walgreens for my day meds and another for night meds. So their very few problems in remembering to take my medications.

  • 0 helpful marks

Jul 1, 2010 (Started May 07, 2010)

  • Effectiveness
    Can't tell (for pain)
  • Effectiveness
    Can't tell (for sleep problems)
  • Side effects
    Severe (racing heart feeling)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Jul 1, 2008 (Started Apr 01, 2008)

  • Effectiveness
    None (for Treat my mood condition(s))
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Desipramine