What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

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Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 579 272
Bipolar disorder 400 231
Migraine headaches 110 59
Bipolar II disorder 64 38
Bipolar I disorder 51 35
Bipolar manic episodes 45 34

Show all 110 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 185
Moderate 198
Mild 190
None 184

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients Percentage
Weight gain 147
Hair loss 47
Fatigue 40
Drowsiness 26
Tremor in hands 22
Nausea 19

Show all 212 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients Percentage
1000 mg daily 18
500 mg daily 15
750 mg daily 9
250 mg daily 8
250 mg twice daily 6
1500 mg daily 6
500 mg twice daily 5
1000 mg twice daily 5
2000 mg daily 4
500 mg three times daily 3

See all 29 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 351
Did not seem to work 254
Doctor's advice 178
Other 109
Personal research 34
Expense 31
Course of treatment ended 26
Change in health plan coverage 12
See all 651 patients who've stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients Percentage
Less than 1 month 2
1 - 6 months 10
6 months - 1 year 5
1 - 2 years 13
2 - 5 years 17
5 - 10 years 27
10 years or more 25

Stopped taking Divalproex sodium

Duration Patients Percentage
Less than 1 month 124
1 - 6 months 143
6 months - 1 year 76
1 - 2 years 80
2 - 5 years 129
5 - 10 years 50
10 years or more 58
Adherence
Adherence Evaluations Percentage
Always 595
Usually 115
Sometimes 22
Never taken as prescribed 25
Burden
Burden Evaluations Percentage
Very hard to take 56
Somewhat hard to take 120
A little hard to take 118
Not at all hard to take 463
Cost per month
Cost per month Evaluations Percentage
$200+ 19
$100-199 19
$50-99 34
$25-49 60
< $25 295
Not specified 330

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients Percentage
Lithium Carbonate (Lithium Carbonate ER) 40
Lamotrigine (Lamictal) 23
Topiramate (Topamax) 16
Aripiprazole (Abilify) 10
Carbamazepine (Tegretol) 6

Show all 45 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients Percentage
Lamotrigine (Lamictal) 37
Lithium Carbonate (Lithium Carbonate ER) 12
Carbamazepine (Tegretol) 11
Levetiracetam (Keppra) 11
Oxcarbazepine (Trileptal) 9

Show all 38 treatments patients report switching to

Last updated:

65 patient evaluations for Divalproex sodium

Sep 19, 2017 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for bipolar disorder)
  • Side effects
    Moderate (head pressure)
  • Adherence
    Sometimes
  • Burden
    Somewhat hard to take
Dosage: 500 mg Daily
Cost: < $25 monthly

Apr 9, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for bipolar disorder)
  • Side effects
    Mild (head pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 250 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 250 mg Daily

  • 0 helpful marks

Sep 23, 2016 (Started Feb 28, 2015)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 65 patient evaluations for Divalproex sodium