What is Cyclobenzaprine?

Category: Prescription Drugs

Most popular types: Flexeril Amrix APO-Cyclobenzaprine Show all

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See also: Ketoprofen, Bupivacaine, Amitriptyline, Clonidine, Gabapentin , Ketamine, Cyclobenzaprine

Cyclobenzaprine is a centrally-acting skeletal muscle relaxant used in the treatment of muscle spasm associated with acute painful musculoskeletal conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Muscle spasms 1345 642
Fibromyalgia 1119 485
Pain 730 298
Stiffness/spasticity 152 64
Back pain 115 54

Show all 202 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 79
Moderate 215
Mild 397
None 552

Commonly reported side effects and conditions associated with Cyclobenzaprine

Side effect Patients Percentage
Drowsiness 152
Sleepiness 69
Dry mouth 61
Excessive daytime sleepiness (somnolence) 29
Fatigue 28
Constipation 25

Show all 128 reported side effects

Dosages

Based on patients currently taking Cyclobenzaprine

Dosage Patients Percentage
10mg as needed 45
10 mg daily 40
10 mg three times daily 33
10 mg twice daily 20
5 mg daily 18
5mg as needed 14
5 mg three times daily 9
20 mg daily 7
30 mg daily 6
15 mg daily 5

See all 21 dosages

Why patients stopped taking Cyclobenzaprine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 347
Doctor's advice 186
Other 177
Side effects too severe 144
Course of treatment ended 98
Change in health plan coverage 27
Expense 27
Personal research 18
See all 827 patients who've stopped taking Cyclobenzaprine

Duration

Currently taking Cyclobenzaprine

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 3
6 months - 1 year 7
1 - 2 years 18
2 - 5 years 64
5 - 10 years 68
10 years or more 55

Stopped taking Cyclobenzaprine

Duration Patients Percentage
Less than 1 month 134
1 - 6 months 190
6 months - 1 year 117
1 - 2 years 113
2 - 5 years 169
5 - 10 years 69
10 years or more 46
Adherence
Adherence Evaluations Percentage
Always 724
Usually 293
Sometimes 176
Never taken as prescribed 50
Burden
Burden Evaluations Percentage
Very hard to take 34
Somewhat hard to take 93
A little hard to take 153
Not at all hard to take 963
Cost per month
Cost per month Evaluations Percentage
$200+ 5
$100-199 2
$50-99 12
$25-49 64
< $25 723
Not specified 437

What people switch to and from

Patients started taking Cyclobenzaprine after stopping:

Treatment Patients Percentage
Baclofen (Mylan-Baclofen) 23
Tizanidine (Zanaflex) 17
Carisoprodol (Soma) 10
Methocarbamol (Robaxin) 10
Gabapentin (Neurontin) 7

Show all 32 treatments patients report switching from

Patients stopped taking Cyclobenzaprine and switched to:

Treatment Patients Percentage
Tizanidine (Zanaflex) 52
Baclofen (Mylan-Baclofen) 39
Methocarbamol (Robaxin) 19
Carisoprodol (Soma) 13
Metaxalone (Skelaxin) 9

Show all 32 treatments patients report switching to

Last updated:

105 patient evaluations for Cyclobenzaprine

Nov 10, 2019 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for urinary urgency)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Effectiveness
    Can't tell (for muscle spasms)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 5 mg Daily
Advice & Tips: ineffective and am weaning myself off of this drug
Cost: < $25 monthly

Oct 29, 2018 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for muscle spasms)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Effectiveness
    Major (for urinary urgency)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Started taking again because benefiting side effects are important to me.
Cost: < $25 monthly

Oct 21, 2018 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for muscle spasms)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Unexpected benefit of less urinary urgency and less allergy symptoms.
Cost: < $25 monthly

  • 0 helpful marks

Oct 9, 2017 (Started Oct 15, 2014)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for muscle spasms)
  • Effectiveness
    Moderate (for muscle tension)
  • Effectiveness
    Moderate (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    Moderate (for tension headaches)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: still must take with tramadol and acetaminophen. pain hasn't been too bad of late so haven't really been taking it for pain purposes. i now take it for insomnia with clonazepam. by itself, neither work. again, together it works where other sleep meds have failed.
Cost: < $25 monthly

Mar 30, 2017 (Started Oct 15, 2014)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for muscle spasms)
  • Effectiveness
    Moderate (for muscle tension)
  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    Moderate (for tension headaches)
  • Effectiveness
    Moderate (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: By itself - not really effective. With Tramadol and Acetaminophen, works great! Be aware if taking with other drugs that affect Serotonin, Cyclobenzaprine has the same chemical structure as a TCA (Tricyclic Antidepressant). It just does not have the antidepressant effects.
Cost: < $25 monthly

  • 0 helpful marks

Jan 12, 2017 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Nov 10, 2014 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Oct 14, 2011 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    Mild (drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Mar 15, 2010 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 105 patient evaluations for Cyclobenzaprine