What is Cyclobenzaprine?

Category: Prescription Drugs

Most popular types: Flexeril Amrix APO-Cyclobenzaprine Show all

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See also: Ketoprofen, Bupivacaine, Amitriptyline, Clonidine, Gabapentin , Ketamine, Cyclobenzaprine

Cyclobenzaprine is a centrally-acting skeletal muscle relaxant used in the treatment of muscle spasm associated with acute painful musculoskeletal conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Muscle spasms 1536 652
Fibromyalgia 1286 499
Pain 842 303
Myofascial pain syndrome 301 49
Sciatic neuralgia 164 28

Show all 237 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 79
Moderate 218
Mild 403
None 579

Commonly reported side effects and conditions associated with Cyclobenzaprine

Side effect Patients Percentage
Drowsiness 153
Sleepiness 70
Dry mouth 63
Excessive daytime sleepiness (somnolence) 29
Fatigue 29
Constipation 26

Show all 128 reported side effects

Dosages

Based on patients currently taking Cyclobenzaprine

Dosage Patients Percentage
10mg as needed 26
10 mg three times daily 22
10 mg daily 18
5mg as needed 14
5 mg daily 10
5 mg three times daily 4
10 mg twice daily 4
15 mg daily 3
30 mg daily 3
2 10mg as needed 3

See all 17 dosages

Why patients stopped taking Cyclobenzaprine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 365
Doctor's advice 197
Other 185
Side effects too severe 150
Course of treatment ended 98
Change in health plan coverage 28
Expense 28
Personal research 20
See all 866 patients who've stopped taking Cyclobenzaprine

Duration

Currently taking Cyclobenzaprine

Duration Patients Percentage
1 - 6 months 4
6 months - 1 year 6
1 - 2 years 5
2 - 5 years 27
5 - 10 years 36
10 years or more 40

Stopped taking Cyclobenzaprine

Duration Patients Percentage
Less than 1 month 136
1 - 6 months 190
6 months - 1 year 117
1 - 2 years 114
2 - 5 years 176
5 - 10 years 68
10 years or more 48
Adherence
Adherence Evaluations Percentage
Always 740
Usually 301
Sometimes 185
Never taken as prescribed 53
Burden
Burden Evaluations Percentage
Very hard to take 34
Somewhat hard to take 95
A little hard to take 157
Not at all hard to take 993
Cost per month
Cost per month Evaluations Percentage
$200+ 5
$100-199 2
$50-99 12
$25-49 68
< $25 745
Not specified 447

What people switch to and from

Patients started taking Cyclobenzaprine after stopping:

Treatment Patients Percentage
Baclofen (Mylan-Baclofen) 26
Tizanidine (Zanaflex) 17
Carisoprodol (Soma) 11
Methocarbamol (Robaxin) 10
Gabapentin (Neurontin) 8

Show all 34 treatments patients report switching from

Patients stopped taking Cyclobenzaprine and switched to:

Treatment Patients Percentage
Tizanidine (Zanaflex) 68
Baclofen (Mylan-Baclofen) 67
Methocarbamol (Robaxin) 26
Carisoprodol (Soma) 21
Metaxalone (Skelaxin) 12

Show all 40 treatments patients report switching to

Last updated:

105 patient evaluations for Cyclobenzaprine

Jun 26, 2020 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    Mild (drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Mar 1, 2020 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Jan 12, 2017 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Nov 10, 2014 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Oct 14, 2011 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    Mild (drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Mar 15, 2010 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Nov 10, 2019 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for urinary urgency)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Effectiveness
    Can't tell (for muscle spasms)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 5 mg Daily
Advice & Tips: ineffective and am weaning myself off of this drug
Cost: < $25 monthly

Oct 29, 2018 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for muscle spasms)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Effectiveness
    Major (for urinary urgency)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Started taking again because benefiting side effects are important to me.
Cost: < $25 monthly

Oct 21, 2018 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for muscle spasms)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Unexpected benefit of less urinary urgency and less allergy symptoms.
Cost: < $25 monthly

  • 0 helpful marks

Oct 9, 2017 (Started Oct 15, 2014)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for muscle spasms)
  • Effectiveness
    Moderate (for muscle tension)
  • Effectiveness
    Moderate (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    Moderate (for tension headaches)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: still must take with tramadol and acetaminophen. pain hasn't been too bad of late so haven't really been taking it for pain purposes. i now take it for insomnia with clonazepam. by itself, neither work. again, together it works where other sleep meds have failed.
Cost: < $25 monthly

Mar 30, 2017 (Started Oct 15, 2014)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for muscle spasms)
  • Effectiveness
    Moderate (for muscle tension)
  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    Moderate (for tension headaches)
  • Effectiveness
    Moderate (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: By itself - not really effective. With Tramadol and Acetaminophen, works great! Be aware if taking with other drugs that affect Serotonin, Cyclobenzaprine has the same chemical structure as a TCA (Tricyclic Antidepressant). It just does not have the antidepressant effects.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 105 patient evaluations for Cyclobenzaprine