What is Cyclobenzaprine?

Category: Prescription Drugs

Most popular types: Flexeril Amrix APO-Cyclobenzaprine Show all

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See also: Ketoprofen, Bupivacaine, Amitriptyline, Clonidine, Gabapentin , Ketamine, Cyclobenzaprine

Cyclobenzaprine is a centrally-acting skeletal muscle relaxant used in the treatment of muscle spasm associated with acute painful musculoskeletal conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Muscle spasms 1348 646
Fibromyalgia 1120 488
Pain 733 300
Stiffness/spasticity 152 64
Back pain 115 55

Show all 202 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 79
Moderate 217
Mild 397
None 560

Commonly reported side effects and conditions associated with Cyclobenzaprine

Side effect Patients Percentage
Drowsiness 153
Sleepiness 69
Dry mouth 62
Excessive daytime sleepiness (somnolence) 29
Fatigue 28
Constipation 25

Show all 128 reported side effects

Dosages

Based on patients currently taking Cyclobenzaprine

Dosage Patients Percentage
10mg as needed 34
10 mg daily 30
10 mg three times daily 26
5mg as needed 18
5 mg daily 13
10 mg twice daily 13
5 mg three times daily 5
20 mg daily 4
30 mg daily 3
2 10mg as needed 3

See all 18 dosages

Why patients stopped taking Cyclobenzaprine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 349
Doctor's advice 187
Other 179
Side effects too severe 146
Course of treatment ended 98
Change in health plan coverage 27
Expense 27
Personal research 19
See all 833 patients who've stopped taking Cyclobenzaprine

Duration

Currently taking Cyclobenzaprine

Duration Patients Percentage
1 - 6 months 8
6 months - 1 year 5
1 - 2 years 11
2 - 5 years 45
5 - 10 years 50
10 years or more 46

Stopped taking Cyclobenzaprine

Duration Patients Percentage
Less than 1 month 136
1 - 6 months 190
6 months - 1 year 118
1 - 2 years 113
2 - 5 years 171
5 - 10 years 69
10 years or more 47
Adherence
Adherence Evaluations Percentage
Always 728
Usually 294
Sometimes 180
Never taken as prescribed 51
Burden
Burden Evaluations Percentage
Very hard to take 34
Somewhat hard to take 94
A little hard to take 156
Not at all hard to take 969
Cost per month
Cost per month Evaluations Percentage
$200+ 5
$100-199 2
$50-99 12
$25-49 66
< $25 728
Not specified 440

What people switch to and from

Patients started taking Cyclobenzaprine after stopping:

Treatment Patients Percentage
Baclofen (Mylan-Baclofen) 23
Tizanidine (Zanaflex) 17
Carisoprodol (Soma) 10
Methocarbamol (Robaxin) 10
Gabapentin (Neurontin) 8

Show all 33 treatments patients report switching from

Patients stopped taking Cyclobenzaprine and switched to:

Treatment Patients Percentage
Tizanidine (Zanaflex) 52
Baclofen (Mylan-Baclofen) 40
Methocarbamol (Robaxin) 19
Carisoprodol (Soma) 13
Metaxalone (Skelaxin) 10

Show all 32 treatments patients report switching to

Last updated:

105 patient evaluations for Cyclobenzaprine

Mar 1, 2020 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Jan 12, 2017 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Nov 10, 2014 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Oct 14, 2011 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    Mild (drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Mar 15, 2010 (Started Sep 30, 2006)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Nov 10, 2019 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for urinary urgency)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Effectiveness
    Can't tell (for muscle spasms)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 5 mg Daily
Advice & Tips: ineffective and am weaning myself off of this drug
Cost: < $25 monthly

Oct 29, 2018 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for muscle spasms)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Effectiveness
    Major (for urinary urgency)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Started taking again because benefiting side effects are important to me.
Cost: < $25 monthly

Oct 21, 2018 (Started Jul 18, 2018)

  • Effectiveness
    Can't tell (for muscle spasms)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Unexpected benefit of less urinary urgency and less allergy symptoms.
Cost: < $25 monthly

  • 0 helpful marks

Oct 9, 2017 (Started Oct 15, 2014)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for muscle spasms)
  • Effectiveness
    Moderate (for muscle tension)
  • Effectiveness
    Moderate (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    Moderate (for tension headaches)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: still must take with tramadol and acetaminophen. pain hasn't been too bad of late so haven't really been taking it for pain purposes. i now take it for insomnia with clonazepam. by itself, neither work. again, together it works where other sleep meds have failed.
Cost: < $25 monthly

Mar 30, 2017 (Started Oct 15, 2014)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for muscle spasms)
  • Effectiveness
    Moderate (for muscle tension)
  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    Moderate (for tension headaches)
  • Effectiveness
    Moderate (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: By itself - not really effective. With Tramadol and Acetaminophen, works great! Be aware if taking with other drugs that affect Serotonin, Cyclobenzaprine has the same chemical structure as a TCA (Tricyclic Antidepressant). It just does not have the antidepressant effects.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 105 patient evaluations for Cyclobenzaprine