What is Codeine-acetaminophen (paracetamol)?

Category: Prescription Drugs

Most popular types: Tylenol with Codeine #3 Co-codamol Tylenol with Codeine #4 Show all

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See also: Codeine

Codeine is in a group of drugs called narcotic pain relievers. Acetaminophen is a less potent pain reliever that increases the effects of codeine. The combination of acetaminophen and codeine is used to relieve moderate to severe pain.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Pain 633 245
Fibromyalgia 220 68
Headaches 101 21
Migraine headaches 45 12
Back pain 29 15

Show all 149 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 23
Moderate 93
Mild 109
None 115

Commonly reported side effects and conditions associated with Codeine-acetaminophen (paracetamol)

Side effect Patients Percentage
Constipation 69
Sleepiness 16
Drowsiness 12
Nausea 12
Chronic constipation 8
Dizziness 8

Show all 64 reported side effects

Dosages

Based on patients currently taking Codeine-acetaminophen (paracetamol)

Dosage Patients Percentage
300-15mg as needed 2
300-30mg as needed 2
1 other twice daily 1
2 tablet(s) twice daily 1
6 tablet(s) daily 1
6 tab(s) daily 1
8 tablet(s) daily 1
5 mg twice daily 1
64 tablet(s) daily 1
50 mg three times daily 1

See all 22 dosages

Why patients stopped taking Codeine-acetaminophen (paracetamol)

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 69
Doctor's advice 59
Other 44
Side effects too severe 38
Course of treatment ended 30
Personal research 8
Change in health plan coverage 5
See all 207 patients who've stopped taking Codeine-acetaminophen (paracetamol)

Duration

Currently taking Codeine-acetaminophen (paracetamol)

Duration Patients Percentage
1 - 6 months 2
6 months - 1 year 1
2 - 5 years 3
5 - 10 years 5
10 years or more 13

Stopped taking Codeine-acetaminophen (paracetamol)

Duration Patients Percentage
Less than 1 month 43
1 - 6 months 40
6 months - 1 year 35
1 - 2 years 25
2 - 5 years 36
5 - 10 years 13
10 years or more 13
Adherence
Adherence Evaluations Percentage
Always 193
Usually 80
Sometimes 55
Never taken as prescribed 12
Burden
Burden Evaluations Percentage
Very hard to take 9
Somewhat hard to take 29
A little hard to take 53
Not at all hard to take 249
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 1
$25-49 16
< $25 160
Not specified 163

What people switch to and from

Patients started taking Codeine-acetaminophen (paracetamol) after stopping:

Treatment Patients Percentage
Hydrocodone-Acetaminophen (Norco) 17
Tramadol (Ultram) 14
Pregabalin (Lyrica) 4
Ibuprofen (Ibuprofen Prescription) 3
Morphine (Morphine ER) 3

Show all 25 treatments patients report switching from

Patients stopped taking Codeine-acetaminophen (paracetamol) and switched to:

Treatment Patients Percentage
Tramadol (Ultram) 22
Hydrocodone-Acetaminophen (Norco) 11
Codeine (Codeine Contin) 6
Gabapentin (Neurontin) 4
Fentanyl patch (Duragesic) 3

Show all 31 treatments patients report switching to

Last updated:

30 patient evaluations for Codeine-acetaminophen (paracetamol)

Jun 14, 2019 (Started Jun 30, 2016)

  • Effectiveness
    Major (for migraine)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks

Aug 22, 2016 (Started Jan 01, 2002)

  • Effectiveness
    None (for pain)
  • Side effects
    Moderate (constipation)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: constipation

Jul 1, 2015 (Started Jan 01, 2002)

  • Effectiveness
    Slight (for pain)
  • Side effects
    Severe (constipation)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: As needed
Cost: < $25 monthly
Side effects: constipation

Jun 18, 2011 (Started Jan 01, 2002)

  • Effectiveness
    Moderate (for pain)
  • Side effects
    Severe (constipation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Causes severe constipation so I only take it when I absolutely have too.
Cost: < $25 monthly
Side effects: constipation

  • 0 helpful marks

May 3, 2014 (Started Aug 01, 2008)

  • Effectiveness
    Slight (for migraine headaches)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: is no better than less less expensive analgesics
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 30 patient evaluations for Codeine-acetaminophen (paracetamol)