What is Clomipramine?

Category: Prescription Drugs

Most popular types: Anafranil

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See also: Anafranil

A tricyclic antidepressant used to treat people with obsessive-compulsive disorder (OCD). It is also used in the treatment of depression, panic attacks and pain.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Obsessive-compulsive disorder 124 26
Depressed mood 27 15
Obsessive thinking 18 10
Major depressive disorder 12 6
Cataplexy 3 0

Show all 30 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 10
Moderate 21
Mild 14
None 12

Commonly reported side effects and conditions associated with Clomipramine

Side effect Patients Percentage
Dry mouth 13
Weight gain 6
Constipation 3
Decreased sex drive (libido) 3
Sexual dysfunction 3
Confusion 2

Show all 51 reported side effects

Dosages

Based on patients currently taking Clomipramine

Dosage Patients Percentage
75 mg twice daily 2
25 mg daily 1
50 mg daily 1
75 mg daily 1

Why patients stopped taking Clomipramine

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 24
Did not seem to work 21
Doctor's advice 15
Other 11
Personal research 3
Change in health plan coverage 1
Course of treatment ended 1
Expense 1
See all 53 patients who've stopped taking Clomipramine

Duration

Currently taking Clomipramine

Duration Patients Percentage
1 - 6 months 1
6 months - 1 year 1
2 - 5 years 1
10 years or more 3

Stopped taking Clomipramine

Duration Patients Percentage
Less than 1 month 10
1 - 6 months 5
6 months - 1 year 7
1 - 2 years 8
2 - 5 years 17
5 - 10 years 1
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 45
Usually 7
Sometimes 2
Never taken as prescribed 3
Burden
Burden Evaluations Percentage
Very hard to take 5
Somewhat hard to take 6
A little hard to take 10
Not at all hard to take 36
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 0
$50-99 2
$25-49 2
< $25 16
Not specified 36

What people switch to and from

Patients started taking Clomipramine after stopping:

Treatment Patients Percentage
Fluoxetine (Prozac) 3
Clonazepam (Klonopin) 2
Duloxetine (Cymbalta) 2
Alprazolam (Xanax) 1
Amitriptyline (Elavil) 1

Show all 20 treatments patients report switching from

Patients stopped taking Clomipramine and switched to:

Treatment Patients Percentage
Bupropion (Wellbutrin) 3
Fluoxetine (Prozac) 2
Fluvoxamine (Luvox) 2
Venlafaxine (Effexor XR) 2
Amitriptyline (Elavil) 1

Show all 15 treatments patients report switching to

Last updated:

4 patient evaluations for Clomipramine

Jul 17, 2020 (Started May 15, 1999)

  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    Moderate (for obsessive-compulsive disorder)
  • Effectiveness
    Slight (for obsessive thinking)
  • Effectiveness
    Moderate (for chronic pain)
  • Side effects
    Mild (constipation, confusion, dry mouth)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 50 mg Twice daily

Jun 16, 2020 (Started May 15, 1999)

  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    Slight (for obsessive-compulsive disorder)
  • Effectiveness
    Slight (for obsessive thinking)
  • Effectiveness
    Moderate (for chronic pain)
  • Side effects
    Mild (constipation, confusion, dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Twice daily

May 31, 1999 (Started May 15, 1999)

  • Effectiveness
    None (for chronic pain)
  • Effectiveness
    None (for pain)
  • Side effects
    Moderate (constipation, confusion, dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

Jun 29, 2017 (Started Jul 01, 2017)

  • Effectiveness
    Can't tell (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for obsessive-compulsive disorder)
  • Side effects
    Moderate (blurry vision, dry mouth, dry eyes)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 225 mg Daily
Advice & Tips: It was useful for OCD (reduced the time wasted with compulsions) but did not help with mood, concentration or anything else

  • 0 helpful marks

Apr 15, 2012 (Started Dec 21, 2010)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Mild (constipation, excessive daytime sleepiness (somnolence), apathy, dry mouth, tiredness, hunger)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: As needed
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

Dec 21, 2010 (Started Dec 21, 2010)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), apathy, dry mouth, tiredness, hunger)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: Daily
Advice & Tips: The impact was definitely noticeable for me. major side effect was constipation, which eventually caused me to search for other solutions
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

Oct 14, 2010 (Started Dec 21, 2010)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (excessive daytime sleepiness (somnolence), apathy, dry mouth, tiredness, hunger)
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips: I have dysthymia, and alot of other drugs didn't work for me - but this was. after about 3 weeks I started to feel the full effect. small side effects - dry mouth felling, and a bit of more tiredness
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

  • 0 helpful marks
Last updated:
Showing 3 of 4 patient evaluations for Clomipramine