What is Clomipramine?

Category: Prescription Drugs

Most popular types: Anafranil

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See also: Anafranil

A tricyclic antidepressant used to treat people with obsessive-compulsive disorder (OCD). It is also used in the treatment of depression, panic attacks and pain.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Obsessive-compulsive disorder 47 23
Depressed mood 26 15
Obsessive thinking 17 8
Major depressive disorder 11 6
Generalized anxiety disorder 2 1

Show all 29 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 10
Moderate 21
Mild 12
None 12

Commonly reported side effects and conditions associated with Clomipramine

Side effect Patients Percentage
Dry mouth 12
Weight gain 6
Decreased sex drive (libido) 3
Sexual dysfunction 3
Constipation 2
Decreased appetite 2

Show all 51 reported side effects

Dosages

Based on patients currently taking Clomipramine

Dosage Patients Percentage
25 mg daily 2
75 mg daily 1
75 mg twice daily 1
75 mg three times daily 1

Why patients stopped taking Clomipramine

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 23
Did not seem to work 19
Doctor's advice 15
Other 10
Personal research 3
Change in health plan coverage 1
Course of treatment ended 1
Expense 1
See all 50 patients who've stopped taking Clomipramine

Duration

Currently taking Clomipramine

Duration Patients Percentage
Less than 1 month 1
6 months - 1 year 1
10 years or more 3

Stopped taking Clomipramine

Duration Patients Percentage
Less than 1 month 10
1 - 6 months 5
6 months - 1 year 7
1 - 2 years 8
2 - 5 years 17
5 - 10 years 1
10 years or more 2
Adherence
Adherence Evaluations Percentage
Always 44
Usually 6
Sometimes 2
Never taken as prescribed 3
Burden
Burden Evaluations Percentage
Very hard to take 5
Somewhat hard to take 6
A little hard to take 9
Not at all hard to take 35
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 0
$50-99 2
$25-49 2
< $25 16
Not specified 34

What people switch to and from

Patients started taking Clomipramine after stopping:

Treatment Patients Percentage
Fluoxetine (Prozac) 3
Duloxetine (Cymbalta) 2
Alprazolam (Xanax) 1
Amitriptyline (Elavil) 1
Atomoxetine (Strattera) 1

Show all 18 treatments patients report switching from

Patients stopped taking Clomipramine and switched to:

Treatment Patients Percentage
Bupropion (Wellbutrin XL) 2
Fluoxetine (Prozac) 2
Amitriptyline (Elavil) 1
Duloxetine (Cymbalta) 1
Escitalopram (Lexapro) 1

Show all 14 treatments patients report switching to

Last updated:

4 patient evaluations for Clomipramine

Jun 29, 2017 (Started Jul 01, 2017)

  • Effectiveness
    Can't tell (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for obsessive-compulsive disorder)
  • Side effects
    Moderate (blurry vision, dry mouth, dry eyes)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 225 mg Daily
Advice & Tips: It was useful for OCD (reduced the time wasted with compulsions) but did not help with mood, concentration or anything else

  • 0 helpful marks

Apr 15, 2012 (Started Dec 21, 2010)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Mild (constipation, excessive daytime sleepiness (somnolence), apathy, dry mouth, tiredness, hunger)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: As needed
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

Dec 21, 2010 (Started Dec 21, 2010)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), apathy, dry mouth, tiredness, hunger)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: Daily
Advice & Tips: The impact was definitely noticeable for me. major side effect was constipation, which eventually caused me to search for other solutions
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

Oct 14, 2010 (Started Dec 21, 2010)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (excessive daytime sleepiness (somnolence), apathy, dry mouth, tiredness, hunger)
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips: I have dysthymia, and alot of other drugs didn't work for me - but this was. after about 3 weeks I started to feel the full effect. small side effects - dry mouth felling, and a bit of more tiredness
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

  • 0 helpful marks

Dec 22, 2008 (Started Jul 20, 2007)

  • Effectiveness
    Slight (for obsessive thinking)
  • Side effects
    Moderate (dry mouth)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Side effects: dry mouth

  • 0 helpful marks
Last updated:
Showing 3 of 4 patient evaluations for Clomipramine