What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin Wellbutrin XL Bupropion XL Show all

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Bupropion is a type of antidepressant. It may be used to treat certain types of depression, such as major depressive disorder and seasonal affective disorder. It may also be used to help quit smoking and for the treatment of attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 16189 1425
Depressed mood 1900 854
Persistent depressive disorder (dysthymia) 1252 343
Mild depression 702 75
Tobacco use disorder 167 45
Reactive depression 152 18

Show all 204 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 299
Moderate 408
Mild 667
None 1253

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients Percentage
Dry mouth 117
Anxious mood 74
Weight gain 60
Insomnia 56
Headaches 50
Constipation 46

Show all 381 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients Percentage
300 mg daily 54
150 mg daily 45
100 mg daily 21
450 mg daily 19
75 mg daily 9
100 mg twice daily 8
200 mg twice daily 8
150 mg twice daily 7
300 mg/24 hours daily 6
150 mg/24 hours daily 5

See all 37 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 764
Side effects too severe 606
Doctor's advice 463
Other 310
Course of treatment ended 102
Expense 90
Personal research 77
Change in health plan coverage 46
See all 1791 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients Percentage
Less than 1 month 2
1 - 6 months 3
6 months - 1 year 9
1 - 2 years 19
2 - 5 years 75
5 - 10 years 66
10 years or more 58

Stopped taking Bupropion

Duration Patients Percentage
Less than 1 month 384
1 - 6 months 365
6 months - 1 year 243
1 - 2 years 235
2 - 5 years 302
5 - 10 years 135
10 years or more 74
Adherence
Adherence Evaluations Percentage
Always 2046
Usually 388
Sometimes 62
Never taken as prescribed 131
Burden
Burden Evaluations Percentage
Very hard to take 93
Somewhat hard to take 158
A little hard to take 371
Not at all hard to take 2005
Cost per month
Cost per month Evaluations Percentage
$200+ 17
$100-199 29
$50-99 91
$25-49 199
< $25 1217
Not specified 1074

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients Percentage
Sertraline (Zoloft) 112
Fluoxetine (Prozac) 108
Venlafaxine (Effexor XR) 89
Duloxetine (Cymbalta) 64
Citalopram (Celexa) 62

Show all 57 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients Percentage
Duloxetine (Cymbalta) 90
Venlafaxine (Effexor XR) 82
Sertraline (Zoloft) 76
Citalopram (Celexa) 48
Escitalopram (Lexapro) 48

Show all 53 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Oct 9, 2020 (Started Mar 10, 2013)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg/24 hours Daily
Cost: < $25 monthly

Nov 11, 2018 (Started Mar 10, 2013)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Severe (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg/24 hours Daily
Cost: < $25 monthly

  • 0 helpful marks

Dec 8, 2019 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 175 mg Daily
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Jul 8, 2018 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 175 mg Daily
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Dec 18, 2013 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Oct 20, 2010 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Aug 30, 2010 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Jul 16, 2009 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

  • 0 helpful marks

Jul 1, 2019 (Started Feb 25, 2011)

  • Effectiveness
    Moderate (for mild depression)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (shaky hands, jittery feeling)
  • Adherence
    Never taken as prescribed
  • Burden
    A little hard to take
Dosage: 150 mg/24 hours Daily
Advice & Tips: If you can't even write you name because the shakes are too much, change to something else.

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion