What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin Wellbutrin XL Bupropion XL Show all

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Bupropion is a type of antidepressant. It may be used to treat certain types of depression, such as major depressive disorder and seasonal affective disorder. It may also be used to help quit smoking and for the treatment of attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 16181 1417
Depressed mood 1896 847
Persistent depressive disorder (dysthymia) 1249 342
Mild depression 700 74
Tobacco use disorder 167 45
Reactive depression 152 18

Show all 203 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 298
Moderate 405
Mild 665
None 1243

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients Percentage
Dry mouth 117
Anxious mood 74
Weight gain 59
Insomnia 56
Headaches 50
Constipation 46

Show all 373 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients Percentage
150 mg daily 57
300 mg daily 55
450 mg daily 23
100 mg daily 20
75 mg daily 11
200 mg twice daily 11
150 mg twice daily 10
300 mg/24 hours daily 8
100 mg twice daily 7
150 mg/24 hours daily 6

See all 44 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 763
Side effects too severe 606
Doctor's advice 463
Other 310
Course of treatment ended 102
Expense 90
Personal research 77
Change in health plan coverage 46
See all 1788 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 9
6 months - 1 year 11
1 - 2 years 22
2 - 5 years 84
5 - 10 years 70
10 years or more 74

Stopped taking Bupropion

Duration Patients Percentage
Less than 1 month 383
1 - 6 months 365
6 months - 1 year 242
1 - 2 years 235
2 - 5 years 304
5 - 10 years 134
10 years or more 72
Adherence
Adherence Evaluations Percentage
Always 2035
Usually 385
Sometimes 62
Never taken as prescribed 129
Burden
Burden Evaluations Percentage
Very hard to take 93
Somewhat hard to take 154
A little hard to take 369
Not at all hard to take 1995
Cost per month
Cost per month Evaluations Percentage
$200+ 17
$100-199 29
$50-99 91
$25-49 199
< $25 1210
Not specified 1065

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients Percentage
Sertraline (Zoloft) 111
Fluoxetine (Prozac) 107
Venlafaxine (Effexor XR) 88
Duloxetine (Cymbalta) 64
Citalopram (Celexa) 62

Show all 57 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients Percentage
Duloxetine (Cymbalta) 91
Venlafaxine (Effexor XR) 82
Sertraline (Zoloft) 76
Escitalopram (Lexapro) 48
Citalopram (Celexa) 47

Show all 53 treatments patients report switching to

Last updated:

187 patient evaluations for Bupropion

Dec 8, 2019 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 175 mg Daily
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Jul 8, 2018 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 175 mg Daily
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Dec 18, 2013 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Oct 20, 2010 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Aug 30, 2010 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Jul 16, 2009 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

  • 0 helpful marks

May 10, 2019 (Started Apr 27, 2019)

  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily

  • 0 helpful marks

Apr 27, 2019 (Started Mar 28, 2019)

  • Effectiveness
    Moderate (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 150 mg Twice daily

  • 0 helpful marks
Last updated:
Showing 3 of 187 patient evaluations for Bupropion