What is Amantadine?

Category: Prescription Drugs

Most popular types: Symmetrel PK Merz amantadine ER Show all

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See also: Amantadine-amitriptyline-baclofen-clonidine-lidocaine-nifedipine-prilocaine

Amantadine is used to treat Parkinson's Disease and "parkinson-like" symptoms such as stiffness and shaking that may be caused by the use of certain drugs. It is also an antiviral medication that may be used to treat and prevent certain strains of influenza A.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 4532 680
Fatigue 643 332
Excessive daytime sleepiness (somnolence) 95 61
Jerky movements 45 28
Tremor(s) 40 40
Stiffness/spasticity 38 11

Show all 116 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 98
Moderate 146
Mild 218
None 633

Commonly reported side effects and conditions associated with Amantadine

Side effect Patients Percentage
Dry mouth 22
Constipation 19
Fatigue 18
Blurry vision 13
Blotchy skin on my legs 12
Nausea 12

Show all 166 reported side effects

Dosages

Based on patients currently taking Amantadine

Dosage Patients Percentage
100 mg twice daily 16
100 mg three times daily 8
200 mg daily 6
100 mg daily 3
200 mg twice daily 3
300 mg daily 2
1 mg daily 1
2 capsule(s) daily 1
1 tablet(s) three times daily 1
2 capsule(s) twice daily 1

See all 16 dosages

Why patients stopped taking Amantadine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 305
Side effects too severe 196
Doctor's advice 145
Other 67
Course of treatment ended 23
Expense 20
Personal research 17
Change in health plan coverage 3
See all 618 patients who've stopped taking Amantadine

Duration

Currently taking Amantadine

Duration Patients Percentage
1 - 6 months 3
6 months - 1 year 2
1 - 2 years 2
2 - 5 years 10
5 - 10 years 19
10 years or more 13

Stopped taking Amantadine

Duration Patients Percentage
Less than 1 month 102
1 - 6 months 178
6 months - 1 year 92
1 - 2 years 70
2 - 5 years 94
5 - 10 years 40
10 years or more 13
Adherence
Adherence Evaluations Percentage
Always 828
Usually 157
Sometimes 38
Never taken as prescribed 72
Burden
Burden Evaluations Percentage
Very hard to take 33
Somewhat hard to take 54
A little hard to take 153
Not at all hard to take 855
Cost per month
Cost per month Evaluations Percentage
$200+ 10
$100-199 35
$50-99 24
$25-49 72
< $25 538
Not specified 416

What people switch to and from

Patients started taking Amantadine after stopping:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 13
Pramipexole (Mirapex) 11
Ropinirole (Requip) 6
Rasagiline (Azilect) 5
Selegiline (Emsam) 4

Show all 18 treatments patients report switching from

Patients stopped taking Amantadine and switched to:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 29
Modafinil (Provigil) 13
Pramipexole (Mirapex) 6
Rasagiline (Azilect) 6
Ropinirole (Requip) 6

Show all 24 treatments patients report switching to

Last updated:

110 patient evaluations for Amantadine

Aug 26, 2021 (Started Mar 20, 2002)

  • Effectiveness
    Can't tell (for jerky movements)
  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    Mild (for Overall)
  • Side effects
    Mild (for Mottling Of Skin On Legs)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Four times daily

Oct 22, 2016 (Started Mar 20, 2002)

  • Effectiveness
    Can't tell (for jerky movements)
  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None (for Overall)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I don't have any advice, a tip might be to listen to your body
Cost: $25-49 monthly

Jan 29, 2016 (Started Mar 20, 2002)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Effectiveness
    Can't tell (for jerky movements)
  • Side effects
    None (for Overall)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I have been taking Amantadine so long, I don't know what it does anymore or if it helps with Dyskinesia or not.
Cost: $50-99 monthly

Sep 19, 2008 (Started Mar 20, 2002)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None (for Overall)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily

  • 0 helpful marks

Feb 24, 2021 (Started Jan 19, 2012)

  • Effectiveness
    Moderate (for tremor in right wrist and hand during walking arm swing)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (for Overall) (muscle and joint pain, nausea)
  • Side effects
    Moderate (for Insomnia)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 200 mg Daily

Jun 27, 2018 (Started Jan 19, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Major (for tremor in right wrist and hand during walking arm swing)
  • Side effects
    Mild (for Overall) (muscle and joint pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: I had to stop working at Lowe's because my symptoms go worse. The neurologist change my dosage to 200 mg twice day and it's working well so I went to work doing private care for a friend who has MS. Things are definitely working out
Cost: $25-49 monthly

Dec 30, 2016 (Started Jan 19, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Major (for tremor in right wrist and hand during walking arm swing)
  • Side effects
    Mild (for Overall) (muscle and joint pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Now that I have found the right cocktail I've been able to return to work full time. after being on disability for almost three years . so far it's been two months since I went back and I'm going strong . Don't get me wrong there are days when I'm exhausted from the nine hour day but it's a good kind of exhausted .
Cost: $100-199 monthly

Apr 16, 2014 (Started Jan 19, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (for Overall) (muscle and joint pain, nausea)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Cost: $100-199 monthly

Mar 11, 2012 (Started Jan 19, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (for Overall) (muscle and joint pain, nausea)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

Jan 8, 2012 (Started Jan 19, 2012)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Major (for tremor in right wrist and hand during walking arm swing)
  • Side effects
    Mild (for Overall)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: It took me several trips to the Neurologist before we found the right drug cocktail. Now that I have found the right cocktail I've been able to return to work full time. after being on disability for almost three years . so far it's been two months since I went back and I'm going strong .  Don't get me wrong there are days when I'm exhausted from the nine hour day but it's a good kind of exhausted .  
Cost: $25-49 monthly

  • 0 helpful marks

Dec 27, 2019 (Started May 15, 2017)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Moderate (for Overall) (tremor(s), paroxysmal dyskinesia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

May 15, 2017 (Started May 15, 2017)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    Severe (for Overall)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Advice & Tips: I had mis read the doctors instructions. I was supposed to start with one tablet every morning and after two weeks if there was no improvement go to one tablet in the morning and one tablet in the evening. I stsrted with one tblet in the morning and one in the evening. It was too much. In a week I am going to try again with the correct dosage
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 110 patient evaluations for Amantadine