What is Amantadine?

Category: Prescription Drugs

Most popular types: Symmetrel PK Merz Mantidan Show all

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See also: Amantadine-amitriptyline-baclofen-clonidine-lidocaine-nifedipine-prilocaine

Amantadine is used to treat Parkinson's Disease and "parkinson-like" symptoms such as stiffness and shaking that may be caused by the use of certain drugs. It is also an antiviral medication that may be used to treat and prevent certain strains of influenza A.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 971 604
Fatigue 586 313
Excessive daytime sleepiness (somnolence) 85 59
Jerky movements 45 29
Stiffness/spasticity 37 11
Tremor(s) 36 35

Show all 110 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 97
Moderate 130
Mild 196
None 581

Commonly reported side effects and conditions associated with Amantadine

Side effect Patients Percentage
Dry mouth 23
Constipation 17
Fatigue 16
Blurry vision 13
Blotchy skin on my legs 12
Nausea 12

Show all 159 reported side effects

Dosages

Based on patients currently taking Amantadine

Dosage Patients Percentage
100 mg twice daily 35
100 mg daily 34
200 mg daily 29
100 mg three times daily 18
300 mg daily 6
100 mg four times daily 4
200 mg twice daily 4
400 mg daily 4
1 tablet(s) daily 1
2.5 mg twice daily 1

See all 16 dosages

Why patients stopped taking Amantadine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 284
Side effects too severe 181
Doctor's advice 139
Other 64
Course of treatment ended 21
Personal research 16
Expense 14
Change in health plan coverage 2
See all 573 patients who've stopped taking Amantadine

Duration

Currently taking Amantadine

Duration Patients Percentage
1 - 6 months 3
6 months - 1 year 3
1 - 2 years 16
2 - 5 years 34
5 - 10 years 48
10 years or more 39

Stopped taking Amantadine

Duration Patients Percentage
Less than 1 month 99
1 - 6 months 173
6 months - 1 year 91
1 - 2 years 69
2 - 5 years 92
5 - 10 years 40
10 years or more 12
Adherence
Adherence Evaluations Percentage
Always 768
Usually 132
Sometimes 35
Never taken as prescribed 69
Burden
Burden Evaluations Percentage
Very hard to take 33
Somewhat hard to take 49
A little hard to take 134
Not at all hard to take 788
Cost per month
Cost per month Evaluations Percentage
$200+ 10
$100-199 32
$50-99 25
$25-49 66
< $25 499
Not specified 372

What people switch to and from

Patients started taking Amantadine after stopping:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 12
Pramipexole (Mirapex) 7
Ropinirole (Requip) 6
Rasagiline (Azilect) 5
Selegiline (Zelapar) 4

Show all 16 treatments patients report switching from

Patients stopped taking Amantadine and switched to:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 17
Modafinil (Provigil) 9
Pramipexole (Mirapex) 6
Rasagiline (Azilect) 5
Ropinirole (Requip) 5

Show all 23 treatments patients report switching to

Last updated:

112 patient evaluations for Amantadine

Jun 27, 2018 (Started Jan 19, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Major (for tremor in right wrist and hand during walking arm swing)
  • Side effects
    Mild (muscle and joint pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: I had to stop working at Lowe's because my symptoms go worse. The neurologist change my dosage to 200 mg twice day and it's working well so I went to work doing private care for a friend who has MS. Things are definitely working out
Cost: $25-49 monthly

Dec 30, 2016 (Started Jan 19, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Major (for tremor in right wrist and hand during walking arm swing)
  • Side effects
    Mild (muscle and joint pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Now that I have found the right cocktail I've been able to return to work full time. after being on disability for almost three years . so far it's been two months since I went back and I'm going strong . Don't get me wrong there are days when I'm exhausted from the nine hour day but it's a good kind of exhausted .
Cost: $100-199 monthly

Apr 16, 2014 (Started Jan 19, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (muscle and joint pain, nausea)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Cost: $100-199 monthly

Mar 11, 2012 (Started Jan 19, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (muscle and joint pain, nausea)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

Jan 8, 2012 (Started Jan 19, 2012)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Major (for tremor in right wrist and hand during walking arm swing)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: It took me several trips to the Neurologist before we found the right drug cocktail. Now that I have found the right cocktail I've been able to return to work full time. after being on disability for almost three years . so far it's been two months since I went back and I'm going strong .  Don't get me wrong there are days when I'm exhausted from the nine hour day but it's a good kind of exhausted .  
Cost: $25-49 monthly

  • 0 helpful marks

Jun 6, 2018 (Started Feb 11, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Advice & Tips: Amantadine helps with dyskinesia. Also, I notice if I take it before I get out of bed, I feel a bit restless and need to get up.
Cost: < $25 monthly

Mar 6, 2017 (Started Feb 11, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Advice & Tips: no new info to report
Cost: < $25 monthly

Sep 23, 2016 (Started Feb 11, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: No change.
Cost: < $25 monthly

Feb 1, 2015 (Started Feb 11, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I still take this. No changes
Cost: < $25 monthly

Oct 1, 2011 (Started Feb 11, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: This did not seem to decrease the dyskiinesia caused by l-dopa.
Cost: < $25 monthly

Aug 23, 2011 (Started Feb 11, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I was prescribed this medicine because I was experiencing dyskenisia effect from levodopa. It helps, but it is not perfect. I can still feel some movement.
Cost: < $25 monthly

  • 1 helpful mark

Apr 15, 2018 (Started Oct 15, 2017)

  • Effectiveness
    None (for fatigue)
  • Side effects
    Moderate (blurry vision)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: < $25 monthly

Oct 24, 2017 (Started Oct 15, 2017)

  • Effectiveness
    None (for fatigue)
  • Side effects
    Moderate (blurry vision)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Every other day
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 112 patient evaluations for Amantadine