• Effectiveness

  Slight (for sleeplessness)
• Side effects

  Severe (for Overall) (dry eyes, dry mouth, dry throat)
• Adherence

  Always
• Burden

  Somewhat hard to take

Advice & Tips: Side effect caused $3500 in dental work (estimate by Dr Humble, DDS).

Cost: < $25 monthly

Side effects: dry eyes, dry throat, dry mouth

• Effectiveness

  None (for sleeplessness)
• Side effects

  Moderate (for Overall) (dry eyes, dry mouth, dry throat)
• Adherence

  Always
• Burden

  Not at all hard to take

Cost: < $25 monthly

Side effects: dry eyes, dry throat, dry mouth

• Effectiveness

  None (for Other)
• Side effects

  None (for Overall)
• Adherence

  Never taken as prescribed
• Burden

  Not at all hard to take

Dosage: 25 mg Daily

• Effectiveness

  Slight (for depressed mood)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 150 mg Daily

Cost: < $25 monthly

• Effectiveness

  Moderate (for unrefreshing or poor sleep)
• Side effects

  Mild (for Overall) (difficulty waking up)
• Adherence

  Always
• Burden

  A little hard to take

Dosage: 50 mg Daily

Advice & Tips: Upped dose is all

• Effectiveness

  None (for depressed mood)
• Effectiveness

  None (for pain)
• Effectiveness

  None (for fibromyalgia)
• Side effects

  Severe (for Overall) (balance problems, brain fog, memory problems, vertigo)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 10 mg Daily

• Effectiveness

  Major (for depressed mood)
• Effectiveness

  Major (for amyotrophic lateral sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 50 mg Daily

Side effects: bladder problems

• Effectiveness

  Moderate (for amyotrophic lateral sclerosis)
• Side effects

  Moderate (for Overall) (bladder problems)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 25 mg Daily

Side effects: bladder problems

• Effectiveness

  None (for amyotrophic lateral sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  A little hard to take

Dosage: 25 mg Daily

Advice & Tips: i havebeen diagnosed with Sensory Neuropathy. This is the reason why I take this drug to control burning sensations to the skin.

Side effects: bladder problems

• Effectiveness

  Moderate (for pain)
• Effectiveness

  Moderate (for fibromyalgia)
• Effectiveness

  Slight (for depressed mood)
• Side effects

  Moderate (for Overall) (dry mouth, constipation with occasional impaction, difficulty waking up)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 50 mg Daily

Advice & Tips: My dosage was incrementally increased 10 mg at a time. With the initial 10mg, I had a little bit of dry mouth and constipation at first. The dry mouth stopped after a short time, and the constipation was very manageable with fiber...until the last 10mg. When I moved up to 50mg the dry mouth returned and has persisted, and the constipation is decidedly harder to manage. If I miss the fiber pills or don't drink enough water for a single day, there are repercussions (and I have plenty of fiber in my diet too). This last increment also affected my sleep for better and worse: I can now fall asleep quite easily, stay pretty soundly asleep, and wake up feeling rested (very good), but it also makes me sleep for very long periods--10, 12, even 14 hours. I have found it difficult to wake up if I've slept less than that. (not good!). It's hard to describe, but there's a sort of heaviness that's come with this last 10mg. I've had a particularly hard time with concentration and thinking through work related issued. I'm not sure if that's all the fibromyalgia, or if the med is actually contributing. In terms of depression--which is what this stuff was originally meant to address--I'd say, I'm a bit more cheerful than I was, but at the same still feeling very negative. It's like I'm a bit depressed, but it seems to matter less. That said, the fear of not being able to make a living eats at me a lot, and the loss of focus makes that a genuine issue, so there's real stress too. Hard to parse this out. Meanwhile, the med doesn't entirely get rid of my fibromyalgia pain, but does definitely make it ignorable on most days and nights. I am now six weeks on with this dosage and both the dry and constipation continue. It's possible that the long, long sleeps might be improving...not quite sure yet. I'm waiting to see if these side effects abate with a little more time. Will go confer with my m.d. soon. By the way, when I was on a much lower dose--maybe it was 20mg or 30mg, I accidentally let my prescription run out, and was without it for a few days. On day 3, I find myself vomiting on the side of the road. Learned my lesson, and I'm religious about taking this every day.

Cost: < $25 monthly

• Effectiveness

  Slight (for fibromyalgia)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 20 mg Daily

Cost: < $25 monthly

• Effectiveness

  Moderate (for peripheral neuropathy)
• Side effects

  Mild (for Overall) (dry mouth)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 25 mg Daily

Cost: < $25 monthly

Side effects: dry mouth

• Effectiveness

  None (for migraine headaches)
• Side effects

  Severe (for Overall) (constipation, ringing in ears (tinnitus), hiccups (hiccoughs), memory problems, cognitive confusion, dry eyes, panic attacks, confusion, urinary problems)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 10 mg Daily

Cost: < $25 monthly

Side effects: dry eyes, confusion, urinary problems, memory problems, cognitive confusion, hiccups (hiccoughs), ringing in ears (tinnitus), panic attacks, constipation

• Effectiveness

  None (for migraine headaches)
• Side effects

  Moderate (for Overall) (constipation, ringing in ears (tinnitus), hiccups (hiccoughs), memory problems, cognitive confusion, dry eyes, panic attacks, confusion, urinary problems)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 10 mg Daily

Side effects: dry eyes, confusion, urinary problems, memory problems, cognitive confusion, hiccups (hiccoughs), ringing in ears (tinnitus), panic attacks, constipation

• Effectiveness

  None (for migraine headaches)
• Side effects

  Mild (for Overall) (ringing in ears (tinnitus), hiccups (hiccoughs), dry eyes)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 20 mg Daily

Side effects: dry eyes, confusion, urinary problems, memory problems, cognitive confusion, hiccups (hiccoughs), ringing in ears (tinnitus), panic attacks, constipation