• Effectiveness

  None (for pain)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 2.4 mg Daily

Advice & Tips: Naltrexone is added to the Embeda, but in a lower dose. I was taking 9mgs. of Naltrexone, it has been lowered to 1.2 mgs. twice a day

Cost: $25-49 monthly

• Effectiveness

  None (for pain)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 9 mg Daily

Advice & Tips: LDN DID HELP WITH SOME OF THE FATIGUE,SLEEPING PROBLEMS, ANXIETY AND DEPTESSION FOR A WHILE. DID NOTHING FOR THE PAIN

Cost: $25-49 monthly

• Effectiveness

  Moderate (for pain)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 9 mg Daily

Advice & Tips: This had cut the widespread body pain by 50%, fatigue by 50%, has helped IBS, improvment in depression and anxiety, decreased mind fog by 75%. Severe chronis pain has been cut by 25%. Increased dosage to see if pain can be decreased more that 25%.

Cost: < $25 monthly

• Effectiveness

  Moderate (for pain)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 9 mg Daily

Advice & Tips: LDN works on each person differently. It has helped with the fatigue, mind fog, have more energy, but found that this didn't last for more than 12 hours. Pain would start, had to rest and be careful not to overdo. Have started second dose, 12 hours apart. Am now getting sleep, which was a major problem before LDN.

Cost: < $25 monthly

• Effectiveness

  Moderate (for pain)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Advice & Tips: I've lived with severe chronic pain for many years. Also fibro, cfs, ra, neurropathy, and degenerative disk and joint disease. I'v been on every class two narcotic that they make, also taking Vicoden as a breakthrough. I haven't taken any narcotics in over 5 weeks thanks to LDN. I take 4.5 mgs at nite, am going to ask rhumy about taking LDN twice daily.

Cost: < $25 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 50 mg Monthly

Advice & Tips: LDN - Naltrexone has helped me with Fatigue problems and slowing down the progression in Multiple Sclerosis

Cost: < $25 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 50 mg Monthly

Advice & Tips: I take it in liquid form

Cost: < $25 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 50 mg Monthly

Advice & Tips: GREAT i take 1ml per night, major FATIGUE problems have gone !!!

Cost: < $25 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 50 mg Monthly

Advice & Tips: It has helped me with the MAJOR fatigue problems i did have before !!! Now since using LDN for nearly two years and one of the first males to try this drug in Australia for M.S, i no longer have these fatigue problems WOW !!! please send me a email before you try this drug and i can explain how i take it.

Cost: < $25 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 50 mg Monthly

Cost: < $25 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Cost: $25-49 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  Mild (for Overall) (occasional insomnia, insomnia)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Cost: $50-99 monthly

• Effectiveness

  Moderate (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Cost: $50-99 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Advice & Tips: This medication's given me some very un-expected increase in heat tolerance.

Cost: $50-99 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Cost: $50-99 monthly

• Effectiveness

  Major (for multiple sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Advice & Tips: This medication is FDA approved for MS in "compounded" form only. If an MS patient can obtain a prescription for this medication (many neurologists won't consider writing a script for this), they'll need to have access to a "compounding" pharmacy. As with all medications, success rates appear to vary. Many people who I know that are using LDN have realized dramatic, if not astonishing symptomatic relief in addition to less disease activity. Some that I know tried it for a period of time without any noticible relief or change & thus stopped using it. Success rates have seemed to depend on dosage level, at least from my observations. Some using LDN notice change almost immediately at the lower dosage levels. Others, as noted above, realize no change at any dosage level. Personally, the symptom relief that I've noticed most is an increase in heat tolerance. As far as my overall success rate, I'd say this medication has done very well in slowing the progression. I've gone over 15 months without having an exacerbation or needing IV solu-medrol. 11 of those months have been since I began using LDN, & I'm not using highest dosage. Maintaining my mobility level & being essentially symptom free for this period of time is very unusual (& quite pleasant!) for me; especially over the last 3 yrs. Note: neurologists/MS specialists might recommend a dormant period of time between stopping a current medication (Beta-Seron, Avonex, etc.) & the beginning of LDN use.

Cost: $50-99 monthly

• Effectiveness

  Major (for fibromyalgia)
• Effectiveness

  Moderate (for fatigue)
• Side effects

  Mild (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Advice & Tips: My nails and hair seem fuller and shinier and stronger. My previously bleeding gums are seemingly miraculously healed. My eyesight seems to be more clear, and im needing my glasses less often.

Cost: $25-49 monthly

• Effectiveness

  Major (for fibromyalgia)
• Effectiveness

  Moderate (for fatigue)
• Side effects

  Mild (for Overall)
• Adherence

  Always
• Burden

  A little hard to take

Advice & Tips: Because I have recently stopped taking Lyrica which helped me sleep, Ive gone down to 4.5mg of LDN every OTHER day. I still have great pain relief and cant inagine going back to my pre LDN pain levels. I havnt had a sniffly nose or a sore throat in almost 3 months which is incredible, since I had a sore throat for almost 2 years before LDN, and had several bouts of asthma, bronchitis and sinusitis all through the year for the last 5 years. LDN has impacted my life in such a positive way, Im still dealing with getting off Lyrica and Cymbalta.... but I know that once I get all those CRAP DRUGS out of my system and level out on the LDN, its gonna be all good!

Cost: $25-49 monthly

• Effectiveness

  Moderate (for fibromyalgia)
• Effectiveness

  Slight (for fatigue)
• Side effects

  Mild (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Advice & Tips: Beg borrow and steal a prescription of LDN if you have all-over pain, cognitive difficulties, a low functioning immune system, and depression. All these have been GREATLY reduced thatnks to LDN. Please get out of your misery and TRY IT! ~Patty

Cost: $25-49 monthly

• Effectiveness

  Major (for fibromyalgia)
• Side effects

  Mild (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Advice & Tips: Im in day 13 of LDN and 90% of my pain is gone, my tender points are not painful and I can have a bowel movement again, Its an amazing medication. I'm still taking 30mg Cymbalta and 150mg Lyrica but plan on titrating down soon. I have increased energy and a little amount of afternoon fatigue. PLEASE if your in pain from Fibromyalgia find a doctor to prescribe LDN for you.

Cost: $25-49 monthly

• Effectiveness

  Major (for fibromyalgia)
• Effectiveness

  Moderate (for fatigue)
• Side effects

  Severe (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Advice & Tips: The drug was AMAZING, FANTASTIC.... BBBUUUTTTT, It made my newly diagnosed Cyclothymia/Bipolar worse, caused some manic side effects, the endorphin rush which was helpful in so many ways, was the very reason I had to stop taking it. It's a damn shame, because now I hurt more than I did before, but having my moods stabilized is a very wonderful thing!!

Cost: $25-49 monthly

• Effectiveness

  Slight (for amyotrophic lateral sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Advice & Tips: I have been on LDL for almost 10 months now - every time I go to the neurologists - he says if there is any change - he can't tell - and to keep doing what I'm doing. So with that said - I will always take LDN -

Cost: $25-49 monthly

• Effectiveness

  Can't tell (for amyotrophic lateral sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Cost: $25-49 monthly

• Effectiveness

  Moderate (for amyotrophic lateral sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Advice & Tips: My chain yawning has been a thing of the past, and I am starting to experience an easier time when food is concerned. There is a noticeable reduction in the number of choking/coughing episodes. My FRS is stable, but this may result from some other aspect of my treatment protocol.

Cost: < $25 monthly

• Effectiveness

  Slight (for amyotrophic lateral sclerosis)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4.5 mg Daily

Advice & Tips: At the three week stage, I am sleeping much better and my ALS chain yawning has ceased. All other ALS symptoms appear stable, but at least three months will have to pass for meaningful results to become evident. My 4.5mg dose is derived from the standard 50mg tablet.

Cost: < $25 monthly

• Effectiveness

  None (for fibromyalgia)
• Side effects

  None (for Overall)
• Adherence

  Usually
• Burden

  A little hard to take

Dosage: 3 mg Daily

Advice & Tips: I was perscribed larger pills to hack down, which was a pain in the butt and probably made for wonky dosages. I seemed to get more restful sleep while taking LDN. Didn't notice anything for my pain though.

• Effectiveness

  Can't tell (for fibromyalgia)
• Side effects

  Mild (for Overall)
• Adherence

  Usually
• Burden

  Not at all hard to take

Dosage: 3 mg Daily

Advice & Tips: Sleeping very well so far. Starting to do things in my sleep I don't remember.

• Effectiveness

  Major (for pain)
• Effectiveness

  Moderate (for fatigue)
• Side effects

  Moderate (for Overall)
• Adherence

  Always
• Burden

  Somewhat hard to take

Dosage: 3 mg Daily

Advice & Tips: I have been doing really well on LDN for the last few months, better energy and much less pain. In the beginning I had some vivid dreams but that passed. In the last 2-3 weeks however, I have begun having vivid bad dreams and even nightmares - as of last night, I am decreasing from 4.5 mg to 3 mg to see if that will eliminate the bad dreams.

• Effectiveness

  Moderate (for primary lateral sclerosis)
• Side effects

  Mild (for Overall) (nausea, hot flashes, antsy)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 1.75 mg Daily

Advice & Tips: to avoid adverse effects, have a snack with LDN find your own optimum dose

Cost: < $25 monthly

Side effects: antsy, hot flashes, nausea

• Effectiveness

  Can't tell (for primary lateral sclerosis)
• Side effects

  Mild (for Overall) (antsy)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 2.5 mg Daily

Advice & Tips: After i week, I would say, expect the unexpected and persevere for a reasonable time. All I hoped for was to look back in a few months and see little or no progression. The balance improvement was a wonderful, unexpected blessing.

Cost: $25-49 monthly

Side effects: antsy, hot flashes, nausea

• Effectiveness

  Major (for Other)
• Effectiveness

  Major (for General health)
• Effectiveness

  Moderate (for cognitive impairment)
• Side effects

  Mild (for Overall) (stiffness in morning)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 4 mg Daily

Advice & Tips: This is not a stand alone treatment.You have to be in optimal health(proper nutrition,supplementation,gluten and casein free,Treating candida albicans and adrenal fatigue should it be a problem) I have only been on this treatment for 1 month but I never had such positive improvements in such a short time frame.No damage of organs is a major positive.I have tried copaxone,betaserone,rebif,tysabri and monthly iv steroids but never had the results so dramatically as ldn.

Cost: $25-49 monthly

Side effects: stiffness in morning