• Effectiveness

  Moderate (for fibromyalgia)
• Side effects

  Moderate (for Overall) (dizziness, brain fog, blurry vision, tiredness, daytime sleepiness, slow to wake in morning, fatigue, problems concentrating)
• Adherence

  Always
• Burden

  A little hard to take

Dosage: 450 mg Daily

Cost: < $25 monthly

Side effects: tiredness, daytime sleepiness, slow to wake in morning, dizziness, blurry vision, fatigue, brain fog, brain fog, problems concentrating

• Effectiveness

  Slight (for nerve pain (neuralgia))
• Side effects

  Moderate (for Overall) (dizziness, brain fog, weight gain, blurry vision, headaches, tiredness, daytime sleepiness, slow to wake in morning, fatigue, problems concentrating)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 450 mg Daily

Side effects: tiredness, daytime sleepiness, slow to wake in morning, dizziness, brain fog, headaches, weight gain, problems concentrating, blurry vision, fatigue

• Effectiveness

  Slight (for pain)
• Effectiveness

  None (for nerve pain (neuralgia))
• Effectiveness

  None (for numbness and tingling with pins and needles)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 300 mg Daily

• Effectiveness

  Major (for numbness and tingling with pins and needles)
• Effectiveness

  Major (for nerve pain (neuralgia))
• Side effects

  Moderate (for Overall) (weight gain)
• Adherence

  Always
• Burden

  Not at all hard to take

Advice & Tips: I love, LOVE the way Lyrica is working. I have stopped my anti-depressant (the pain management seems to have decreased my depression). I do not have to take Klonipin for my RLS because the Lyrica works for it. I have NO pain... NONE!! This after a YEAR and a half of neurontin, ultram, and vicoden for the pain. I JUST take the lyrica, and take a small dose (100-150 mg at night). I also do not have to take the provigil. My fatigue has lessened a great deal. I guess because I am not constantly in pain, my brain and body isn't as tired. HOWEVER!!! I have gained 12 pounds in a month and a half. I had gastric bypass 3 years ago, so gaining weight is UNACCEPTABLE and scares me to death. I would rather be in negligable pain than to gain weight (yes, may be skewed, but as a former/forever morbidly obese person, I do NOT ever want to head in that direction). I will be weaning off of this - trying wellbutrin (my Internist recommended to try it cause it has worked in 60% of ppl for neuropathy pain), then I am going to see if an occasional dose of lyrica will help but keep the weight gain at bay. Going off of this makes me sad, but gaining weight scares me too much.

Cost: < $25 monthly

Side effects: weight gain

• Effectiveness

  Major (for numbness and tingling with pins and needles)
• Effectiveness

  Major (for nerve pain (neuralgia))
• Side effects

  Moderate (for Overall) (weight gain)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 200 mg Daily

Advice & Tips: Got rid of RLS and seemed to improve my depression without the pain, also increased my stamina without the pain, HOWEVER, I gained 12 pounds in 6 weeks, which, for me is unacceptable.

Cost: < $25 monthly

Side effects: weight gain

• Effectiveness

  Major (for numbness and tingling with pins and needles)
• Effectiveness

  Major (for nerve pain (neuralgia))
• Side effects

  Mild (for Overall) (weight gain)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 200 mg Daily

Advice & Tips: This med started working after my FIRST dose. I have been on neurontin for over a year and a half. Told my neurologist I was still having nerve pain, but it was minor and managable. She said lets try Lyrica. Put me on 50 in am and 50 in PM. AMAZING!! I never knew that a small amt of pain could have such a large impact. For the first time in OVER a year and a half, I have been PAIN free for a month. I have stopped my klonipin for severe RLS (been on it for over 5 years), Zoloft for depression, neurontin, take ultram for other aches and pains, but not ever day or nearly that often, and hardly take my vicoden anymore, I don't need it. I also don't need the provigil because I am not so tired because I do not have to fight the pain!

Cost: < $25 monthly

Side effects: weight gain

• Effectiveness

  Can't tell (for fibromyalgia)
• Side effects

  Severe (for Overall) (dizziness, brain fog, blurry vision, headaches, mania, tiredness, intoxicated feeling, problems concentrating)
• Adherence

  Sometimes
• Burden

  Not at all hard to take

Advice & Tips: I had a really weird reaction to this treatment. I got manically hyper, its a strange feeling to know that you are acting in an almost manic fashion and the only thing that is keeping you acting sane is the calm realization in the back of your mind that you have to keep control of it. Then, I took the second dose and went with my familly to the store and felt drunk. Not a little silly, like, overserved drunk. Very weird. Called Dr. and they said that had never happened before and that I should not take any more. Then I was sick as heck for two days after. Awesome, right? Not so much.

Side effects: tiredness, mania, intoxicated feeling, blurry vision, dizziness, brain fog, dizziness, headaches, problems concentrating

• Effectiveness

  Major (for fibromyalgia)
• Side effects

  Severe (for Overall) (dizziness, weight gain, blurry vision, headaches, tiredness, daytime sleepiness, slow to wake in morning, vertigo, fatigue, problems concentrating)
• Adherence

  Sometimes
• Burden

  Very hard to take

Dosage: As needed

Advice & Tips: this medicine works for my pain almost as soon as it gets in my system but the various side effects make it a emergency type of med for me i have to need it very badly and when nothing else works.forget driving or reading anything that requires my attention.

Cost: < $25 monthly

Side effects: tiredness, daytime sleepiness, slow to wake in morning, dizziness, brain fog, headaches, weight gain, vertigo, blurry vision, problems concentrating, fatigue

• Effectiveness

  None (for fibromyalgia)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 100 mg Daily

Advice & Tips: I took this for a month when it first was approved by the FDA & I did not get any relief from it at all. I could not tell any impact it had because it felt like I didn't take anything. So my doctor went back to my Tramadol that I had been taking since it did give me some relief.

• Effectiveness

  Moderate (for fibromyalgia)
• Effectiveness

  Moderate (for pain)
• Effectiveness

  Moderate (for muscle pain)
• Side effects

  Moderate (for Overall) (dizziness, weight gain, blurry vision, headaches, tiredness, daytime sleepiness)
• Adherence

  Always
• Burden

  A little hard to take

Dosage: 600 mg Daily

Cost: $50-99 monthly

Side effects: blurry vision, tiredness, daytime sleepiness, dizziness, headaches, weight gain

• Effectiveness

  None (for nerve pain (neuralgia))
• Side effects

  Moderate (for Overall) (dizziness, brain fog, weight gain, fluid retention (edema), fatigue, problems concentrating)
• Adherence

  Usually
• Burden

  Very hard to take

Dosage: 300 mg Daily

Cost: < $25 monthly

Side effects: fluid retention (edema), weight gain, dizziness, brain fog, problems concentrating, fatigue

• Effectiveness

  Can't tell (for nerve pain (neuralgia))
• Side effects

  Moderate (for Overall) (weight gain, fluid retention (edema))
• Adherence

  Usually
• Burden

  Not at all hard to take

Advice & Tips: I haven't taken this long enough to have any pain relief that I can tell.

Cost: < $25 monthly

Side effects: fluid retention (edema), weight gain, dizziness, brain fog, problems concentrating, fatigue

• Effectiveness

  Moderate (for fibromyalgia)
• Effectiveness

  Moderate (for pain)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 450 mg Daily

Cost: < $25 monthly