24 patient evaluations for Milnacipran with a side effects rating of Severe

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Jul 25, 2013 (Started Nov 27, 2009)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Severe (high blood pressure increased)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Advice & Tips: Make sure you monitor your blood pressure. My blood pressure almost doubled taking this med.

  • 0 helpful marks

Oct 6, 2012 (Started Jun 15, 2012)

  • Effectiveness
    None (for fibromyalgia)
  • Effectiveness
    None (for pain)
  • Side effects
    Severe (serotonin syndrome)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: The reaction between this medication and another medication along with something I ate caused Serotonin Toxicity Syndrome putting me in the hospital for 3 days.
Cost: $25-49 monthly

  • 0 helpful marks

Jul 28, 2012 (Started Jul 28, 2011)

  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    Severe (hot flashes, excessive sweating)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Advice & Tips: I am currently lowering my dosage to discontinue this treatment i take 50 mg a day atm
Cost: < $25 monthly

  • 0 helpful marks

Jul 27, 2012 (Started Jun 30, 2012)

  • Effectiveness
    Major (for pain)
  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Severe (atrial fibrillation, tachycardia (fast heart rate), heart stopped, heart palpitations)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Advice & Tips: Although Savella almost killed me... It did work 99% of my symptoms were gone. I felt like I had a new lease on life. On day 11 I felt weird like my heart was pounding for no reason non-stop
Cost: < $25 monthly

  • 0 helpful marks

Jun 21, 2012 (Started Jun 07, 2012)

  • Effectiveness
    None (for fibromyalgia)
  • Effectiveness
    None (for pain)
  • Side effects
    Severe (dryness)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 12.5 mg Daily

  • 0 helpful marks

May 15, 2012 (Started Apr 25, 2012)

  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    Severe (excessive dry mouth)
  • Adherence
    Never taken as prescribed
  • Burden
    Somewhat hard to take
Dosage: 25 mg Daily
Advice & Tips: I took this for almost 2 months. It caused such dryness in my mouth that my taste buds were hard and swollen. It became painful to swallow.

  • 0 helpful marks

Jan 31, 2012 (Started Dec 30, 2011)

  • Effectiveness
    None (for generalized anxiety disorder)
  • Effectiveness
    None (for depressed mood)
  • Effectiveness
    None (for pain)
  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    Severe (violent thoughts, psychotic symptoms (anxiety depression fear), mood swings)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Didn't see any positive effects, made me feel crazy. I'm normally a very calm, laid back person and it made me feel so violent I try to choke out my Fiance. It was truly like an out of body experience and I called the on call Dr immediately. I was Rx for severe nerve pain for Fibromyalgia. I don't have a history of any form of psychosis, but truly felt like I was not myself. Looking at other people's dosages it looks as though I was given an extremely high dosage right off the bat. However, I'm petrified to ever try it again even at a reasonable dose. Please be careful and question Dr's when they Rx new meds and the dosage sounds too high. Make them titrate the dosage up and the side effects will be less of a shock to your system and will be able to better evaluate the effectiveness of the medication.
Cost: < $25 monthly

  • 0 helpful marks

Aug 1, 2011 (Started Jul 13, 2011)

  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    Severe (nausea, diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Be careful of stomach upset, such as nauseousness and diarrhea. If it continues, talk with your doctor. I let mine go on for 3 weeks, and I became very, very ill. I thought the symptoms would get better with time. Also, be careful of any drug interactions with this drug.
Cost: < $25 monthly
Side effects: nausea, diarrhea

  • 0 helpful marks

May 5, 2011 (Started Jul 03, 2010)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Severe (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Made me extremely tired. Had serotonin syndrome for the second time so my pain mgmt. dr. switched me to Pristiq. It's only been a few days on the Pristiq so it is too soon to tell but I think I got much more pain relief from the Savella, but my mood and energy level are better now. Savella stays in your system longer and can build up and serotonin syndrome is too dangerous to take a chance with. I won't ever be able to take Savella again so now we have to figure out how to help the pain more, it is very severe now. It is nice to have less fatigue!
Cost: $50-99 monthly
Side effects: fatigue

Dec 4, 2010 (Started Jul 03, 2010)

  • Effectiveness
    Can't tell (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 156.25 mg Daily
Advice & Tips: I think the Savella helps a lot with fatigue. I used to be on Cymbalta and was always so tired I could barely function. Had such a hard time staying awake I had to stop watching my great niece until I could get it under control. I had major fatigue before starting Cymbalta but can't honestly say if the fatigue was so bad because of the Cymbalta or if it was just not giving me any help with the fatigue from the fibromyalgia and it was naturally getting worse. Fatigue is much better since I have been on Savella. So either the Savella helps with the fatigue or the Cymbalta was making it worse. Or some combination of the 2.
Cost: $50-99 monthly
Side effects: fatigue

Aug 20, 2010 (Started Jul 03, 2010)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 156.25 mg Daily
Advice & Tips: Great, new drug. I take 1 tablet in the morning, which is easy, and the other mid afternoon, which is harder to remember. Dr. advised me not to take it too close to bedtime so this was his advice. It doesn't help with the pain, but neither has anything else and I have tried many different meds. It does help tremendously with fatigue and that used to be a major problem for me. Nuvigil and Phentermine were useless for me. This is wonderful.
Side effects: fatigue

  • 3 helpful marks

Feb 2, 2011 (Started Jan 01, 2010)

  • Effectiveness
    Slight (for Chronic Pelvic Pain)
  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Severe (elevated blood pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: This drug worked well but my blood pressure went up to 159/100 with a pulse of 102 while sitting. It has gone back to 128/70 pulse 78 since going off Savella
Side effects: elevated blood pressure

Dec 6, 2010 (Started Jan 01, 2010)

  • Effectiveness
    Can't tell (for Chronic Pelvic Pain)
  • Effectiveness
    Can't tell (for fibromyalgia)
  • Side effects
    Moderate (elevated blood pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Check with your doctor as my blood pressure and heart rate went up considerably
Side effects: elevated blood pressure

Jun 10, 2010 (Started Jan 01, 2010)

  • Effectiveness
    Slight (for Chronic Pelvic Pain)
  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Mild (elevated blood pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I went off of this due to High Blood Pressure and didn't realize how much it was helping the pain until I was taken off. I went back on Savella for pain on 5/27/10...noticed difference right away. Sweating, is that from Savella?
Side effects: elevated blood pressure

Jan 7, 2010 (Started Jan 01, 2010)

  • Effectiveness
    Slight (for Chronic Pelvic Pain)
  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: The nausea goes away after a week or two and then some pain relief with gained energy. Side effect though is insommnia but...with less pain.
Side effects: elevated blood pressure

  • 1 helpful mark
Last updated:
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